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1.
颅脑穿刺术治疗高血压脑出血术后再出血危险因素分析   总被引:4,自引:0,他引:4  
目的探讨影响CT监视下颅脑穿刺术治疗高血压脑出血术后再出血的危险因素。方法回顾性分析本院2006年1月至2010年1月CT监视下颅脑穿刺术治疗的490例高血压脑出血患者的临床资料,通过单因素和多因素Logistic回归分析对再出血的可能相关因素进行分析。结果 490例患者再出血48例(9.7%)。手术时机(比值比=2.401,P=0.035)、术中首次抽吸量(比值比=3.012,P=0.001)、术后高血压控制情况(比值比=2.562,P=0.028)、肝脏疾病(比值比=1.987,P=0.037)等4个因素是影响CT监视下颅脑穿刺术后再出血的独立危险因素。结论 CT监视下颅脑穿刺术后再出血主要受手术时机、术中首次抽吸量、术后高血压控制情况、肝脏疾病影响,重视这些因素有利于再出血的早期识别与及时处理。  相似文献
2.
出血性脑梗死危险因素的Logistic回归分析   总被引:4,自引:3,他引:1  
目的探讨出血性脑梗死的危险因素。方法根据专业知识确定与出血性脑梗死有关的因素,采用非条件Logistic回归确定危险因素。结果大面积梗死灶、使用抗凝剂或溶栓治疗、糖尿病史是出血性脑梗死的独立危险因素,与年龄、高血压史、高血脂关系不大。结论大面积脑梗死、使用抗凝剂或溶栓、糖尿病患者发生梗死后出血的几率增大,及时行影像学检查可以早期发现。  相似文献
3.
阿尔茨海默病认知损害程度的相关影响因素分析   总被引:1,自引:1,他引:0  
目的:探讨影响阿尔茨海默病(AD)认知损害程度的相关因素。方法:选择记忆障碍门诊就诊的不同严重程度的AD患者共229例,其中轻度101例,中重度128例,收集相关资料进行条件Logistic回归分析。结果:条件Logistic回归分析显示:病程长、低教育水平、低体重指数及伴发精神行为异常为AD病情严重的独立危险因素,OR值分别为1.729(5%CI:1.318~2.269)、0.854(95%CI:0.791~0.922)、0.853(95%CI:0.780~0.932)及2.865(95%CI:1.527~5.378)。结论:本研究提示病程、教育水平、体重指数及是否合并精神行为异常与AD病情的严重程度有明显相关性。  相似文献
4.
颅脑损脑伤后早期癫痫发作危险因素的Logistic回归分析   总被引:1,自引:0,他引:1  
目的分析颅脑损伤后患者早期癫痫发作(EPTS)的危险因素。方法回顾性分析同济医院神经外科2003年1月至2008年1月收治的336例颅脑损伤患者的临床资料,对颅脑损伤后EPTS的相关临床因素进行单因素分析和Logistic回归分析。结果单因素分析结果显示:患者年龄、GCS评分、外伤后昏迷时间、硬脑膜完整性、有无颅内血肿、有无脑挫伤、血钠水平和有无酗酒史均是EPTS的危险因素(P〈0.05),性别和治疗方式与EPTS相关性较小(P〉0.05),颅脑损伤后EPTS的发生率为8.63%(29/336),患者年龄(OR=0.45802)、外伤后GCS评分(OR=0.870024)、外伤后昏迷时间(OR=4.160461)、硬脑膜完整性(OR=4.833046)和脑挫伤(OR=2.783133)均是外伤后EPTS发生的危险因素。结论患者年龄较小、伤后GCS评分较低、外伤后昏迷时间〉30min、硬脑膜有破损和低钠血症均可以增加颅脑损伤后出现EPTS的危险陛,此研究结果可为癫痫的防治提供参考。  相似文献
5.
抗精神病药物导致的迟发性锥体外系综合征(TES)由迟发性运动障碍(TD)发展而来。TES分TD、迟发性肌张力障碍(TDT)等多个亚型,以TD最多见。TES的治疗无特效方法,因此预防尤为重要。本研究对上海地区七个精神病医疗单位进行普查,诊断TES113例,并采用病例-对照研究设计,对23个相关因素进行Logistic回归分析,推测TES的危险因子。结果发现,年龄、性别、抗胆碱能药物、用药总时间和目前用药量等五个因素在0.05或0.01水平上对TES的存在有显著意义上的作用。氯氮平、急性锥体外系统综合征还不能肯定为危险因子。  相似文献
6.
Research on suicide in correctional facilities has focused on inmates to the neglect of correctional officers. Research on factors such as stress, burnout, and work dissatisfaction has often found high levels of these problems among guards. The present study analyses data from 21 states to ascertain whether guards are at risk of suicide. The results of a multivariate logistic regression analysis indicate that the risk of suicide among guards in 39% higher than that of the rest of the working age population.  相似文献
7.
目的 掌握住院精神分裂症患者体重流行病学资料,分析影响因素。方法 采用国人体重标准衡量,对随机抽取的省,市,县住院精神分裂症患者体重进行流行病学调查及相关因素调查。结果 体重超重得占48.37%,其中肥胖前期占32.61%,肥胖占15.76%。多因素Logistic分析显示;超重的发生与X3(年龄),X11(既往治疗),X16(氯氮平合并维思通)因子呈正相关。与X1(级别),X2(性别),X6(病程)呈负相关。结论 住院精神分裂症患者体重增加明显,其影响因素是多方面的;关注患者体重增加,采取综合措施干预有利于病人身心健康及提高治疗依从性。  相似文献
8.
OBJECTIVE: This semiprospective case-control study was performed to investigate the relationship between harmony-seeking personality and the occurrence of prostate cancer. METHODS: Out of 217 consecutive participants admitted to hospital for biopsy, 86 and 81 were classified into the case and control groups, respectively, based on their initial diagnosis and eligibility criteria. The participants answered several questionnaires after admission. The logistic regression model was used for multivariate analyses to assess the association. RESULTS: "Harmony-seeking personality" was selected as the only psychological variable significantly contributing to the model, while "family history of prostate cancer" as the only somatic variable. "Harmony-seeking" maintained a significant contribution to the model, also including "family history" and even to the model adjusted by "patient prediction of cancer diagnosis" and "prostate-specific antigen" (PSA), probably related to the consequences of the disease. CONCLUSION: The harmony-seeking personality could differentiate between groups of men with and without prostate cancer.  相似文献
9.
目的探讨创伤性蛛网膜下腔出血(tSAH)后脑积水发生的相关危险因素。方法回顾性分析301例tSAH患者,利用Logistic回归分析分别探讨性别、年龄、是否伴有其他脑损害、开颅去骨瓣减压术以及tSAH的部位、范围、厚度等对创伤性脑积水发生的影响。结果301例tSAH患者36例(11.96%)发生脑积水,Logistic回归显示脑积水的发生与患者年龄、伴有其他脑外伤、tSAH范围、tSAH厚度等因素有关,OR值分别为0.415,1.712,2.968,3.875,而与性别、tSAH的部位及开颅去骨瓣减压术无关。结论该结果有助于分析和预见不同患者tSAH性脑积水发生的危险性,提示对高危患者应采取更加积极的治疗手段,从而减少tSAH性脑积水的发生。  相似文献
10.
Objective: Neuroserpin (NSP) is known for its neuroprotective effects. The aim of this study was to investigate the relationship between NSP level and clinical outcomes and inflammatory markers in Chinese patients with acute ischemic stroke.

Methods: A total of 133 patients with acute cerebral infarction (ischemia group) and 44 controls were recruited. The modified Rankin Scale (mRS) was used to determine the functional outcome three months after onset. We investigated the relationship between serum NSP levels [on admission and a decrease in NSP levels (10 days after admission versus on admission)] and serum levels of several inflammatory markers.

Results: We confirmed that NSP levels on admission in the ischemia group were significantly higher than those in the control group. NSP levels in patients with good outcomes were significantly higher than those in patients with poor outcomes. NSP levels on admission were associated with having a good outcome in these patients. We found that a larger decrease in NSP levels (on admission vs. 10 days after admission) was correlated with lower serum levels of IL-6, IL-1β, and ICAM-1 10 days after admission.

Conclusions: A larger decrease in NSP levels related to lower levels of inflammatory marker, while higher NSP levels were associated with lower inflammatory markers and better functional outcomes. Decreasing the infarct size may play a role in this process. These results provide more evidence of the neuroprotective effect of NSP in cerebral ischemic patients. Decrease in the Serum NSP level and NSP level at admission may be considered as potential predictive factors for outcome of acute ischemic stroke.  相似文献

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