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1.
慢性精神分裂症患者生命质量的性别差异   总被引:3,自引:0,他引:3  
目的:探讨长期住院的慢性精神分裂症患者生命质量的性别差异及影响因素。方法:采用健康状况调查问卷(SF-36)、阳性与阴性症状量表(PANSS)、治疗中出现的症状量表(TESS)对连续住院时间超过5年的72例男性、47例女性慢性精神分裂症患者进行评定,选用60名健康自愿者作为对照。结果:男性患者生命质量显菩低于女性;精神病状态、药物种类、药物不良反应、年龄、住院时间对男女生命质量均有影响;男性的生命质量还受病期、婚姻状况的影响。结论:慢性精神分裂症患者的生命质量低下.应给予更多关注。  相似文献
2.
Little is known about the underlying neural processes of playing computer/video games, despite the high prevalence of its gaming behavior, especially in males. In a functional magnetic resonance imaging study contrasting a space-infringement game with a control task, males showed greater activation and functional connectivity compared to females in the mesocorticolimbic system. These findings may be attributable to higher motivational states in males, as well as gender differences in reward prediction, learning reward values and cognitive state during computer video games. These gender differences may help explain why males are more attracted to, and more likely to become "hooked" on video games than females.  相似文献
3.
目的探讨首次脑梗死患者与正常健康体检者血清超敏C-反应蛋白(hsCRP)的性别差异及意义。方法选取1 3 8例首次脑梗死患者(NIHSS评分<5分)作为脑梗死组,将其分为男性组和女性组。选取1 5 0例健康体检者作为正常组,亦分为男性组和女性组。检测各组患者血清hsCRP水平。结果脑梗死组血清hsCRP水平明显高于正常组(P<0.05)。男性脑梗死组与女性脑梗死组血清hsCRP相比较差异无统计学意义(P>0.0 5)。男性正常组与女性正常组血清hsCRP相比较,男性组高于女性组,差异有统计学意义(P<0.0 5)。男性脑梗死组与男性正常组血清hsCRP相比较差异无统计学意义(P>0.0 5)。女性脑梗死组与女性正常组血清hsCRP相比较差异有统计学意义(P<0.0 5)。结论血清hsCRP水平存在性别差异。炎症反应与女性脑梗死的发病可能有着更为密切的联系。  相似文献
4.
保定市精神分裂症性别差异的流行病学调查   总被引:1,自引:0,他引:1  
目的了解保定市精神分裂症的患病率及其性别分布特点。方法2004年10月~2005年3月采用多阶段分层整群抽样方法随机抽取≥18岁的人群,共10073例,用扩展的一般健康问卷(GHQ-12)将调查对象分为高、中、低危险组,采用美国精神障碍诊断标准(DSM-Ⅳ),以美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)轴Ⅰ障碍定式临床检查患者版对调查对象进行精神分裂症的诊断。功能状况评价采用大体功能评定量表(Global Assessment Function,GAF)。结果9021人完成调查,精神分裂症的终生及时点患病率分别为6.20‰、5.42‰,男性3.93‰、3.28‰,女性8.45‰、7.55‰,女性均高于男性(P〈0.01);女性已婚率显著高于男性(P〈0.01),而受教育年数女性显著低于男性(P〈0.01);精神分裂症的临床症状、发病年龄与诊断分型性别比较无显著性差异;女性心理、社会及职业功能受损程度较男性为重(P〈0.05)。精神卫生服务利用的性别间均无显著性差异。结论精神分裂症患者在患病率、婚姻、教育及心理、社会、职业功能均存在性别差异,提示在制定治疗康复方案时,应有所区别。  相似文献
5.
To determine if there are age or gender-related differences in reporting fear as a symptom of epileptic seizure, all clinical charts of patients evaluated at the "C. Munari - Epilepsy Surgery Center" of Milan from 1990 to June 2005 were analyzed, looking for patients with ictal fear. Among the 2,530 clinical charts examined (1,330 male and 1,200 female), 265 patients were found with ictal fear (100 men, 165 women). The gender difference in reporting ictal fear was not so marked in the pediatric age group (98 girls, 74 boys), whereas in adult patients the difference was significant (158 women, 83 men). Interestingly, more men than women (14:3) had ictal fear during childhood that disappeared during adulthood. The literature review confirmed that ictal fear is significantly more common in women, though there is no gender difference in the pediatric age group.  相似文献
6.
Toward an understanding of the cerebral substrates of woman's orgasm   总被引:1,自引:0,他引:1  
The way women experience orgasm is of interest to scientists, clinicians, and laypeople. Whereas the origin and the function of a woman's orgasm remains controversial, the current models of sexual function acknowledge a combined role of central (spinal and cerebral) and peripheral processes during orgasm experience. At the central level, although it is accepted that the spinal cord drives orgasm, the cerebral involvement and cognitive representation of a woman's orgasm has not been extensively investigated. Important gaps in our knowledge remain. Recently, the astonishing advances of neuroimaging techniques applied in parallel with a neuropsychological approach allowed the unravelling of specific functional neuroanatomy of a woman's orgasm. Here, clinical and experimental findings on the cortico-subcortical pathway of a woman's orgasm are reviewed and compared with the neural basis of a man's orgasm. By defining the specific brain areas that sustain the assumed higher-order representation of a woman's orgasm, this review provides a foundation for future studies. The next challenge of functional imaging and neuropsychological studies is to understand the hierarchical interactions between these multiple cortical areas, not only with a correlation analysis but also with high spatio-temporal resolution techniques demonstrating the causal necessity, the temporal time course and the direction of the causality. Further studies using a multi-disciplinary approach are needed to identify the spatio-temporal dynamic of a woman's orgasm, its dysfunctions and possible new treatments.  相似文献
7.
The social play behavior of juvenile rats was originally described nearly a century ago, but research methods have only recently included the controlled laboratory investigation of psychobiological variables. This review covers the experimental literature of social play or play fighting behavior in juvenile laboratory rats reported during the last decade. Innovative measures for quantifying social play are described; hormonal, pharmacological, and neurological variables are examined; and interpretative concepts of social play are discussed. The current emphasis on measures and procedures as well as the limited scope of current research effort suggests a formative stage of research development.  相似文献
8.
The social play behavior of juvenile rats was originally described nearly a century ago, but research methods have only recently included the controlled laboratory investigation of psychobiological variables. This review covers the experimental literature of social play or play fighting behavior in juvenile laboratory rats reported during the last decade. Innovative measures for quantifying social play are described; hormonal, pharmacological, and neurological variables are examined; and interpretative concepts of social play are discussed. The current emphasis on measures and procedures as well as the limited scope of current research effort suggests a formative stage of research development.  相似文献
9.
Summary We present the results of a review of the literature concerning gender differences in age at the onset of schizophrenia. In view of the very consistent finding that the first admission to hospital for schizophrenia occurs on average earlier in men than in women we examined the question whether this is due to the fact that the psychosis manifests itself earlier in men or that the period between first manifestation and admission to hospital is shorter than in women. By means of a metaanalytic approach we then looked for evidence for the existence of local or temporal variations in the degree of gender difference. Lastly, we dealt with the question whether gender differences in age of onset can be observed in other functional psychoses.  相似文献
10.
Summary The psychotic syndrome at the core of schizophrenia appears to be invariable across cultures. The risk of morbidity also seems to vary very little from country to country and over medium periods of time. Moreover, apart from gender differences in first onset, the cumulative lifetime risk is the same in females and males. A similar epidemiological pattern is only found in pathological conditions that are characterized by a precisely defined section of a psychopathological dimension with a continuous distribution in the population, e.g. severe mental retardation being the extreme section of normally distributed IQ values. The interpretation of schizophrenic psychosis as the extreme section of a psychopathological dimension or disposition that is almost evenly distributed in all populations is supported by the fact that milder psychiatric disorders occur more frequently before the onset of the psychosis and in close relatives of schizophrenic patients. The psychopathological heterogeneity of these disorders argues against the assumption of a manifest psychopathological dimension with a continuous transition from the schizophrenic psychosis to the normal schizothymic personality. More probable is a continuously distributed latent vulnerability to schizophrenia — with or without a threshold effect — which in severe degrees disposes to the uniform reaction pattern of the schizophrenia syndrome. Smaller degrees of vulnerability are associated with an increased risk for milder patterns of disturbances, which are also more strongly determined by environment and personality and therefore are rather heterogeneous. These assumptions lead to other epidemiological and genetic models than Kraepelin's early concept of a disease entity does.  相似文献
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