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目的 探讨右美托咪定在功能神经外科手术麻醉中的应用效果.方法 选取2013-02-2014-02于我院行外科手术的患者共150例,按入院顺序号随机将患者分为观察组与对照组各75例.在手术结束前30 min,观察组微量泵注入右美托咪定0.4 μg/kg.对照组注入等容量的0.9%氯化钠溶液.比较2组静注右美托咪定(或生理盐水)10 min后的Ramsay镇静评分,记录术中血流动力异常情况,苏醒时间、清醒拔管时间及不良反应发生情况等.结果 观察组静注右美托咪定10min后的Ramsay镇静评分为(2.7±0.6)分,苏醒时间和拔管时间分别为(25.5±12.4)min、(30.4±5.6)min,显著好于对照组(t=5.269、4.735、4.381,P<0.05).观察组切口缝合时、术后1h、术后2h的脑氧摄取率及动脉-颈内静脉球部血样差均显著好于对照组(P<0.05).观察组不良反应发生率为1.33%,显著低于对照组(x2=9.058,P<0.05).结论 右美托咪定是功能外科手术麻醉的较佳选择,其在临床上的应用具有美好的前景,值得大力推广.  相似文献
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Objective: The use of Deep Brain Stimulation (DBS) has been increasing. It follows the premise of neuromodulation in that it is reversible, as compared to previous lesioning procedures. Materials and Methods: Complications with DBS are inherently low and range from short‐term complications during surgery such as hemorrhage to long‐term complications that include lead fractures and infection. Over time, the authors have experienced indications for additional lead placements or change in position of the lead on the ipsilateral side. There is the inherent possibility of direct contact between leads or the microelectrode. This can lead to malpositioning, displacement of a lead placed previously, and malfunctioning. Result: We report a case in which a lead placed previously becomes displaced during microelectrode recording on the ipsilateral side. Conclusion: This scenario was corrected and had no clinical or functional complication. Placement of an additional ipsilateral DBS lead can be a safe and effective treatment option.  相似文献
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随着神经影像学、神经电生理、立体定向以及神经调控技术的广泛临床应用,功能神经外科疾病的诊治水平有了较快发展,手术定位从影像学解剖定位发展到神经电生理学的定位,立体定向设备从立体定向仪发展到神经导航设备,手术入路的设计从手工计算手术轨迹到计算机设计的手术计划系统,手术方式从脑深部核团立体定向毁损术到神经电刺激技术,促进了功能神经外科向纵深发展.  相似文献
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Lozano AM 《Movement disorders》2011,26(14):2469-2470
The case presented involves an 88-year-old woman with sudden onset of right-sided hemiballism that persisted for an amazing 15 years. The video demonstrates wide amplitude choreic movements of the proximal and distal limbs of the right side, as well as of the axial musculature. Classical teaching dictates that this patient has a lesion in the subthalamic nucleus. Here then is a prime example where classical teaching is wrong!  相似文献
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