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1.
BACKGROUND: Little population-based data exist on the prevalence or correlates of eating disorders. METHODS: Prevalence and correlates of eating disorders from the National Comorbidity Replication, a nationally representative face-to-face household survey (n = 9282), conducted in 2001-2003, were assessed using the WHO Composite International Diagnostic Interview. RESULTS: Lifetime prevalence estimates of DSM-IV anorexia nervosa, bulimia nervosa, and binge eating disorder are .9%, 1.5%, and 3.5% among women, and .3% .5%, and 2.0% among men. Survival analysis based on retrospective age-of-onset reports suggests that risk of bulimia nervosa and binge eating disorder increased with successive birth cohorts. All 3 disorders are significantly comorbid with many other DSM-IV disorders. Lifetime anorexia nervosa is significantly associated with low current weight (body-mass index <18.5), whereas lifetime binge eating disorder is associated with current severe obesity (body-mass index > or =40). Although most respondents with 12-month bulimia nervosa and binge eating disorder report some role impairment (data unavailable for anorexia nervosa since no respondents met criteria for 12-month prevalence), only a minority of cases ever sought treatment. CONCLUSIONS: Eating disorders, although relatively uncommon, represent a public health concern because they are frequently associated with other psychopathology and role impairment, and are frequently under-treated.  相似文献
2.
神经性厌食患者血小板 5-羟色胺浓度的对照研究   总被引:3,自引:1,他引:2  
目的研究5-羟色胺(5-HT)在神经性厌食发病中的作用。方法采用高效液相色谱法,分别测定37例神经性厌食患者和34例正常对照者的血小板5-HT含量。结果神经性厌食患者血小板5-HT水平[(2.2&#177;1.4)nmol/109个血小板]低于正常对照组[(4.4&#177;0.9)nmol/109个血小板],差异有统计学意义(t=-7.845;P〈0.01);两亚型即约束型[(2.4&#177;1.1)nmol/109个血小板]与暴食/清除型[(2.0&#177;1.6)nmol/109个血小板]神经性厌食患者血小板5-HT浓度比较,差异无统计学意义(P〉0.05)。结论本研究结果支持神经性厌食患者5-HT能低下的假说;并提示约束型与暴食/清除型神经性厌食发病有着相同的5-HT机制。  相似文献
3.
脑深部电刺激治疗难治性神经性厌食症   总被引:1,自引:0,他引:1  
目的 探讨脑深部电刺激(DBS)治疗难治性神经性厌食症.方法 4例经过心理及药物治疗无效的难治性神经性厌食症患者,接受磁共振导向立体定向双侧伏隔核DBS植入,术后给予持续慢性高频电刺激.采用身体质量指数(BMI)及其他精神科量表如Yale - Brown强迫症量表(YBOCS)、汉密尔顿焦虑量表(HAMA)评估DBS治疗难治性神经性厌食症的长期疗效.结果 所有患者随访9-50个月(平均39个月).经过3-12个月的慢性电刺激,患者BMI由术前的平均11.4增加到17.9,同时进食行为及强迫、焦虑症状也明显缓解.4例患者的月经均完全恢复正常.其中2例在术后30个月后刺激器因电池耗尽而取出,患者治疗效果稳定,所有患者未出现不良反应及手术并发症.结论 伏隔核DBS是治疗难治性神经性厌食症有效及安全的方法,不仅可改善进食障碍,同时对伴随的强迫焦虑症状也有明显改善.  相似文献
4.
奥氮平治疗神经性厌食症   总被引:1,自引:0,他引:1  
目的:观察奥氮平治疗神经性厌食症的临床疗效。方法:10例神经性厌食症住院患者,给予奥氮平2.5~5mg/d治疗。于治疗前后测量体质量,比较治疗前后体质量变化。结果:出院时患者体质量平均增加(3.40±2.63)kg,体质量指数平均增加(1.30±0.99),有效率为50%。体质量变化与住院天数存在明显正相关(r=0.736,P=0.015)。结论:小剂量奥氮平治疗神经性厌食症具有一定疗效,耐受性好。  相似文献
5.
神经性厌食症患者父母的生命质量研究   总被引:1,自引:0,他引:1  
目的探讨神经性厌食症患者父母的生命质量。方法使用SF-36健康评定量表对44例神经性厌食症患者父母的健康相关生命质量进行测评。结果长病程组患者父母SF-36量表各维度平均分数均低于短病程组患者父母,且精神健康(MH)维度及总分存在显著差异(P&lt;0.05)。结论神经性厌食症患者的病程影响患者父母的生命质量。  相似文献
6.
Memory bias in anorexia nervosa: evidence from directed forgetting   总被引:1,自引:0,他引:1  
The aim of this study was to examine memory bias for disorder-relevant information in anorexia nervosa by using the directed forgetting paradigm. Normal controls and patients with anorexia nervosa were given a list consisting of neutral and disorder-relevant words, which they were either asked to remember (R) or forget (F). Memory performance was measured by a free recall and a Yes/No recognition task for all items. There was a directed forgetting effect for both groups; however, the magnitude of the effect (difference between R and F words) was smaller for the patient group due to higher recall of F items. Further analyses showed that this was true only for disorder-relevant but not for neutral items. Our findings support the existence of a strong memory bias for disorder-relevant information in patients with anorexia nervosa, who had difficulty in avoiding the processing of information that they were asked to forget.  相似文献
7.
Psychiatric Comorbidities among Female Adolescents with Anorexia Nervosa   总被引:1,自引:0,他引:1  
This study investigated current comorbid Axis I diagnoses associated with Anorexia Nervosa (AN) in adolescents. The sample included 101 female adolescents treated at a psychiatric unit for primary DSM-IV diagnoses of AN. 73.3% of the AN patients were diagnosed as having a current comorbidity of at least one comorbid Axis I diagnosis, with no differences across AN subtypes. Mood disorders (60.4%) were most commonly identified, followed by the category anxiety disorders without obsessive-compulsive disorders (OCD) (25.7%), OCD (16.8%) and substance use disorders (7.9%). Two specific diagnoses differed across the two subtypes of AN. Substance use disorder was 18 times, and the category anxiety disorder without OCD was three times as likely to co-occur with AN binge-eating disorder and purging type than with AN restricting type. Clinicians should be alerted to the particularly high rate of psychiatric comorbidities in adolescents suffering from AN.  相似文献
8.
Elevated plasma homocysteine levels have been found in different psychiatric disorders, including major depression and eating disorders. The aim of the present study was to evaluate whether presence of depression or depressive symptoms is associated with elevated homocysteine levels in patients with eating disorders. Total plasma homocysteine levels were assessed in 44 females with anorexia nervosa (n = 21) or bulimia nervosa (n = 23). Comorbid major depressive disorder (MDD) was diagnosed according to DSM-IV criteria using a semi-structured interview (SCID-I). Furthermore, depressive symptoms were assessed using Beck's depression inventory (BDI). Presence of MDD was not associated with elevated homocysteine levels (t-test: T = 0.42; df = 42; P = 0.68). However, self-rated presence of clinically relevant depressive symptoms (BDI score18) was associated with elevated homocysteine (T = -2.8; df = 42; P = 0.008). Presence of depressive symptoms may explain elevated homocysteine levels previously reported in patients with eating disorders or vice versa. Longitudinal studies are needed to unravel this hen or egg problem.  相似文献
9.
家谱图在神经性厌食症患者治疗中的应用   总被引:1,自引:0,他引:1  
目的探讨神经性厌食家谱图的特征以及在心理治疗中的作用。方法对12例门诊神经性厌食症患者采用与患者一起绘制家谱图的形式,以结构式家庭治疗理论对家谱图进行解释、分析。结果12例家谱图显示:多数神经性厌食症患者的家庭存在着家庭结构的不良和功能失调。结论家谱图在神经性厌食症的治疗中,对于揭示家庭结构和功能的不良、规划治疗的方向、评价治疗的效果以及激发患者和家庭的内省等方面起到了积极而重要的作用。  相似文献
10.
Zusammenfassung Psychodiagnostische Untersuchungen mit dem Rorschach-Test wurden an einer Gruppe anorektischer Patienten durchgeführt.Während sich die Anorexie-Patienten von normalgesunden Kontrollpersonen unterscheiden, finden sich im Vergleich mit einer eigenen parallelisierten Kontrollgruppe von nichtanorektischen neurotischen Patienten keine kennzeichnenden Unterschiede.Dies führt zur Annahme, daß das klinische Bild in seiner Endstrecke nicht durch spezifische psychodynamische Faktoren, als vielmehr durch die im Test nicht erfaßbaren Faktoren wie somatische Disposition, Entgegenkommen der Organe bzw. Regressionstiefe mitbestimmt ist.  相似文献
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