Which gastric cancer patients could benefit from staging laparoscopy? A GIRCG multicenter cohort study

BackgroundThis study aimed to investigate which gastric cancer patients could benefit the most from staging laparoscopy.MethodsA retrospective cohort study was carried out, including 316 (216 cM- and 100 cM+) gastric cancer patients who had undergone staging laparoscopy between 2010 and 2020 in seven GIRCG centers. A model including easily-accessible clinical, biochemical and pathological markers was constructed to predict the risk of carcinomatosis. ROC curve and decision curve analyses were used to verify its accuracy and net benefit.ResultsIn the cM-population staging laparoscopy could detect 67 cases who had peritoneal carcinomatosis or positive cytology, for a yield of 30.5%. In cM-patients, intestinal type tumors (0.25, 0.12–0.51; p = 0.002), cT4 tumors (2.18, 1.11–4.28; p = 0.023) and cancers of the lower third (0.31, 0.14–0.70; p = 0.004) were associated with the presence of peritoneal carcinomatosis and/or positive cytology. The ROC curve analysis of the model including the three variables showed an AUC of 0.75 (0.68–0.81, p < 0.001). The decision curve analyses showed that the model had a higher net benefit than the treating all strategy between threshold probabilities of 15 and 50%.ConclusionsStaging laparoscopy is a useful tool to address the patient with gastric cancer to the most adequate treatment. In cM-patients the assessment of the location of the tumor, the Lauren's histotype and the cT status may help in providing additional elements in indicating or not the use of staging laparoscopy.     

Abdominal access techniques

This article discusses the variety of techniques available to gain safe exposure to intra-abdominal organs. In recent years there have been significant advances in these techniques with a move towards minimally invasive strategies as the gold standard of care. This article will discuss the various options available, including laparoscopy and traditional open access, as well as the use of robotics within abdominal surgery.     

腹腔镜精准肝切除术治疗原发性肝癌的临床效果

目的探究腹腔镜精准肝切除术治疗原发性肝癌的临床效果。方法选择2019年1月—2020年6月期间在医院接受腹腔镜肝切除术治疗的80例原发性肝癌患者作为实验分析对象,依据手术治疗方案的不同将患者分为腹腔镜常规肝切除组(对照组)40例和腹腔镜精准肝切除组(观察组)40例,对两组患者手术各项指标、手术前后肝功能指标改善情况及术后并发症发生率进行对比分析。结果观察组患者手术时间明显长于对照组,组间比较进行t检验,差异具有统计学意义(P<0.05);观察组患者术中出血量及术中输血量均少于对照组患者,术后恢复时间明显短于对照组患者,组间比较进行t检验,差异具有统计学意义(P<0.05);术后,两组患者ALT、AST、ALB及TBIL水平均显著降低,组内比较进行t检验,差异具有统计学意义(P<0.05),观察组患者ALT、AST、ALB及TBIL水平降低幅度显著大于对照组患者,组间比较进行t检验,差异具有统计学意义(P<0.05);观察组患者术后并发症发生率为10.00%,对照组患者术后并发症发生率为27.50%,组间比较进行χ2检验,差异具有统计学意义(χ2=4.021;P=0.045)。结论与腹腔镜常规肝切除术比较,腹腔镜精准肝切除术操作精细,手术时间相对较长,患者术中出血量更少,术后恢复时间更短,能够最大限度保护患者的肝脏,减低患者术后并发症发生率,提高手术治疗效果,改善患者预后。     

A case of diaphragmatic hernia incarceration after a heart transplant operation

We report a case of a diaphragmatic hernia after a heart transplant operation. A 43-year-old woman, who underwent orthotropic heart transplantation for hypertrophic cadiomyopathy two year earlier, presented with vomiting and epigastric pain. A computed tomography scan showed that the stomach and transverse colon were dislocated in the left thoracic cavity. We diagnosed left diaphragmatic hernia incarceration and performed laparoscopic repair of the diaphragmatic hernia. A 12 × 8 cm diaphragmatic defect was found intraoperatively on the ventrolateral aspect of the left diaphragm, and the stomach with volvulus had herniated into the thorax through the defect. The hernia was considered to be iatrogenic. The diaphragmatic defect was large, and the diaphragm was thinning. We closed the defect by mesh repair. Laparoscopic mesh repair of the diaphragmatic hernia could be performed safely and with minimal invasiveness.     

Laparoscopy for living donor left nephrectomy: Comparison of three‐dimensional and two‐dimensional vision

The main objective of this preliminary study was to evaluate the feasibility and safety of 3‐D laparoscopic living donor left nephrectomy (LDLN). The secondary objective was to compare intraoperative and postoperative outcomes between 3‐D and 2‐D laparoscopic LDLN. All patients who underwent a laparoscopic LDLN from January 2015 to April 2018 in a university center were included. All surgeries were performed by three experienced surgeons. Seventy three patients were included the following: 16 underwent a 3‐D laparoscopic LDLN (3‐D group), and 57 underwent a 2‐D laparoscopic LDLN (2‐D group). Operative time and warm ischemia time (WIT) were significantly lower in the 3‐D group (operative time: 80.9 ± 10.2 vs 114.1 ± 32.3 minutes in the 3‐D and 2‐D groups, P = .0002) (WIT: 1.7 ± 0.6 vs 2.3 ± 0.9 minutes in the 3‐D and 2‐D groups, P = .02). No conversion to open surgery occurred in both groups. Length of hospital stay was significantly shorter in the 3‐D group. No major postoperative complications (Clavien ≥ III) occurred. One‐year postoperative GFR was similar to 3‐D and 2‐D groups. Our preliminary study demonstrates that 3‐D laparoscopic LDLN is a feasible and safe surgical procedure. Intraoperative and postoperative outcomes were similar in both 2‐D and 3‐D vision systems, but 3‐D vision systems allow reduction in WIT and operative time.     

经阴道单孔腹腔镜子宫肌瘤剔除术的应用

目的经阴道单孔腹腔镜手术是新兴的经自然腔道内镜手术之一，它具有无体表瘢痕、术后疼痛减轻等特点，它在妇科领域的应用越来越广泛。本文旨在探究经阴道单孔腹腔镜子宫肌瘤剔除术的手术技巧及应用难点。 方法选取广州医科大学附属第三医院1例子宫肌瘤病例，逐步讲解经阴道单孔腹腔镜子宫肌瘤剔除术的手术步骤及方法，演示手术技巧。 结果手术顺利完成，术中出血量少，术后病理提示坏死性肌瘤。患者的左下腹疼痛得到了缓解。术后随访3个月，患者恢复良好，无并发症。 结论经阴道单孔腹腔镜子宫肌瘤剔除术是可行的，可以有效地清除病灶。但该术式对手术医师的技术提出了更高的要求，学习曲线延长，并且需要远期随访及进一步研究来评估其安全性。     

腹腔镜根治性切除治疗肝门部胆管癌15例分析

目的 探讨腹腔镜根治性切除治疗肝门部胆管癌的可行性及安全性。方法 回顾性分析2013年5月至2018年5月在川北医学院附属医院行根治性手术治疗并经病理学检查证实的15例肝门部胆管癌病人的临床资料，分析术中及术后情况，并随访观察。结果 15例肝门部胆管癌病人中13例行完全腹腔镜手术，2例病人中转开放手术。手术时间为（404.3±62.8）min，术中出血（502.0±133.8）mL，术后住院时间为（9.6±2.7）d，术后首次排气时间为（3.2±0.8）d。术后淋巴结检出数目为（9.5±2.6）枚，1例发现N2淋巴结转移。术后发生胆漏1例，大量腹腔积液1例，切口脂肪液化1例，均经保守治疗后好转出院。所有病人均获得随访，截至2018年5月，随访时间为6～60个月，死亡4例。结论 通过术前充分评估及术中探查制定相应手术策略，并且在严格掌握手术适应证的前提下，由具备丰富腹腔镜手术经验的医生主持操作，腹腔镜技术应用于肝门部胆管癌病人相对安全、可行。     

腹腔镜与开腹手术治疗子宫内膜癌的疗效比较

目的:探讨腹腔镜与传统开腹手术治疗子宫内膜癌的临床效果差异。方法:回顾性分析陕西省人民医院2013年10月至2018年3月114例确诊为子宫内膜癌并以腹腔镜治疗的患者为研究对象（腹腔镜组），以同期62例开腹手术治疗的子宫内膜癌病例为对照组，两组在手术时间、术中出血量、淋巴结清扫个数、术后膀胱功能恢复时间、排气时间、体温恢复时间、住院时间及并发症等各方面指标进行比较。结果:腹腔镜组术中失血量、输血率、术后体温恢复时间、肠道功能恢复时间、膀胱功能恢复时间、术后住院天数及手术并发症发生率显著低于开腹组(P<0.05)。腹腔镜组与开腹组在手术时间、术中清扫淋巴结数目、复发率及总生存率差异无统计学意义。结论:与传统方法相比，腹腔镜手术短期效果良好，生存率相当，在具备丰富的腹腔镜手术经验、完善的腹腔镜设备的条件下，可以广泛应用于子宫内膜癌患者的治疗。