全文获取类型
收费全文 | 26104篇 |
免费 | 2422篇 |
国内免费 | 585篇 |
专业分类
耳鼻咽喉 | 1140篇 |
儿科学 | 301篇 |
妇产科学 | 127篇 |
基础医学 | 2204篇 |
口腔科学 | 1693篇 |
临床医学 | 2545篇 |
内科学 | 1185篇 |
皮肤病学 | 118篇 |
神经病学 | 1955篇 |
特种医学 | 1282篇 |
外国民族医学 | 1篇 |
外科学 | 8654篇 |
综合类 | 3323篇 |
现状与发展 | 1篇 |
预防医学 | 676篇 |
眼科学 | 454篇 |
药学 | 1067篇 |
20篇 | |
中国医学 | 561篇 |
肿瘤学 | 1804篇 |
出版年
2024年 | 20篇 |
2023年 | 454篇 |
2022年 | 557篇 |
2021年 | 990篇 |
2020年 | 1230篇 |
2019年 | 1063篇 |
2018年 | 904篇 |
2017年 | 994篇 |
2016年 | 1121篇 |
2015年 | 1070篇 |
2014年 | 1802篇 |
2013年 | 2216篇 |
2012年 | 1510篇 |
2011年 | 1650篇 |
2010年 | 1368篇 |
2009年 | 1379篇 |
2008年 | 1246篇 |
2007年 | 1233篇 |
2006年 | 1092篇 |
2005年 | 1006篇 |
2004年 | 844篇 |
2003年 | 775篇 |
2002年 | 613篇 |
2001年 | 597篇 |
2000年 | 482篇 |
1999年 | 327篇 |
1998年 | 357篇 |
1997年 | 268篇 |
1996年 | 191篇 |
1995年 | 197篇 |
1994年 | 159篇 |
1993年 | 145篇 |
1992年 | 145篇 |
1991年 | 102篇 |
1990年 | 85篇 |
1989年 | 115篇 |
1988年 | 80篇 |
1987年 | 77篇 |
1986年 | 68篇 |
1985年 | 93篇 |
1984年 | 79篇 |
1983年 | 66篇 |
1982年 | 73篇 |
1981年 | 55篇 |
1980年 | 61篇 |
1979年 | 42篇 |
1978年 | 34篇 |
1977年 | 27篇 |
1976年 | 18篇 |
1975年 | 19篇 |
排序方式: 共有10000条查询结果,搜索用时 93 毫秒
1.
2.
《Journal of cranio-maxillo-facial surgery》2022,50(3):225-229
The aim of this study was to investigate the clinical course of masticatory function recovery following arthrocentesis. Patients with a unilateral condylar head fracture who underwent arthrocentesis for therapeutic reasons were evaluated and compared with patients with a unilateral condylar head fracture who did not undergo arthrocentesis. At 3 months after treatment, the occlusal contact area and maximum bite force in patients with a fracture treated with arthrocentesis were greater than in those who did not receive arthrocentesis at the same time points, although the differences were not significant. Moreover, at 1 and 3 months following arthrocentesis, mean (±SD) occlusal contact area (1 month: 1.99 ± 0.55 mm2, p = 0.01; 3 months: 2.90 ± 1.36 mm2, p = 0.03) and maximum bite force (1 month: 82.45 ± 15.04 N, p = 0.01; 3 months: 101.11 ± 14.53 N, p = 0.01) on the fractured side in patients who underwent that treatment were significantly reduced when compared with those on the non-fractured side. The authors conclude that if the priority is to avoid open reduction and internal fixation, then the arthrocentesis approach might be a less invasive alternative, albeit with the price of a prolonged healing interval. 相似文献
3.
4.
5.
6.
Jakub Pazdrowski Aleksandra Daczak‐Pazdrowska Adriana Polaska Joanna Ka
mierska Wojciech Barczak Mateusz Szewczyk Pawe Golusiski Zygmunt Adamski Ryszard aba Wojciech Golusiski 《Skin research and technology》2019,25(6):857-861
Radiodermatitis is one of the commonest side effects of radiotherapy. They are usually assessed by semi‐quantitative clinical scores, which are not validated and may be subject to inter‐observer variability. A few previous studies suggested that high‐frequency ultrasonography (HF‐USG) is useful in the assessment of the acute phase of radiation dermatitis in breast cancer patients. (a) To monitor skin changes by HF‐USG during the course of radiotherapy due to head and neck cancers, and (b) to determine whether there is any connection between skin sonograms and the skin scoring criteria. This prospective, observational study includes patients diagnosed with head and neck cancers, treated with radiotherapy or concomitant chemoradiation. The final analysis includes six patients. In every patient, the HF‐USG as well as dermatological assessment (target lesion score—TLS and CACE v. 4.0) were performed 4×: before, in the middle, day after, and 3 months after radiotherapy. There were significant differences between non‐irradiated skin thickness and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P < .0001), as well as between irradiated, unchanged skin thickness (TLS grade 0) and thickness of skin with clinically obvious radiodermatitis (TLS grade 1‐4; P = .0002). There was no significant difference between non‐irradiated and irradiated, unchanged skin thickness (TLS grade 0; P = .9318). In four patients, we demonstrated subepidermal low echogenic band (SLEB). HF‐USG can be useful tool to noninvasive and objective assessment of skin changes during radiotherapy. 相似文献
7.
目的对比动力髋螺钉(dynamic hip screw,DHS)治疗和股骨近端抗旋髓内钉(proximal femoral nail anti-rotation,PFNA)固定治疗老年股骨粗隆间骨折疗效。方法纳入本院收治的45例采用PFNA固定治疗的老年股骨粗隆间骨折患者作为研究组,研究时间为2017年11月-2018年11月;回顾性分析2016年11月-2017年11月在我院采用DHS治疗的45例老年股骨粗隆间骨折患者的临床资料,作为对照组。记录两组的相关手术指标,观察手术并发症情况。结果研究组的手术时间和骨折愈合时间均短于对照组,术中出血量明显少于对照组,术后疼痛VAS评分均明显低于对照组(P<0.05)。对照组的并发症发生率高于研究组(P<0.05)。结论PFNA固定治疗比DHS治疗老年股骨粗隆间骨折更加安全有效,值得临床借鉴和应用。 相似文献
8.
9.
Y.R. Song B. Wu Y.T. Yang J. Chen L.J. Zhang Z.W. Zhang H.Y. Shi C.L. Huang J.X. Pan P. Xie 《Brazilian journal of medical and biological research》2015,48(11):973-982
Bipolar disorder (BD) is a common psychiatric mood disorder affecting more than 1-2%
of the general population of different European countries. Unfortunately, there is no
objective laboratory-based test to aid BD diagnosis or monitor its progression, and
little is known about the molecular basis of BD. Here, we performed a comparative
proteomic study to identify differentially expressed plasma proteins in various BD
mood states (depressed BD, manic BD, and euthymic BD) relative to healthy controls. A
total of 10 euthymic BD, 20 depressed BD, 15 manic BD, and 20 demographically matched
healthy control subjects were recruited. Seven high-abundance proteins were
immunodepleted in plasma samples from the 4 experimental groups, which were then
subjected to proteome-wide expression profiling by two-dimensional electrophoresis
and matrix-assisted laser desorption/ionization-time-of-flight/time-of-flight tandem
mass spectrometry. Proteomic results were validated by immunoblotting and
bioinformatically analyzed using MetaCore. From a total of 32 proteins identified
with 1.5-fold changes in expression compared with healthy controls, 16 proteins were
perturbed in BD independent of mood state, while 16 proteins were specifically
associated with particular BD mood states. Two mood-independent differential
proteins, apolipoprotein (Apo) A1 and Apo L1, suggest that BD pathophysiology may be
associated with early perturbations in lipid metabolism. Moreover, down-regulation of
one mood-dependent protein, carbonic anhydrase 1 (CA-1), suggests it may be involved
in the pathophysiology of depressive episodes in BD. Thus, BD pathophysiology may be
associated with early perturbations in lipid metabolism that are independent of mood
state, while CA-1 may be involved in the pathophysiology of depressive episodes. 相似文献