收费全文 | 4325篇 |
免费 | 207篇 |
国内免费 | 68篇 |
耳鼻咽喉 | 73篇 |
儿科学 | 376篇 |
妇产科学 | 269篇 |
基础医学 | 579篇 |
口腔科学 | 124篇 |
临床医学 | 459篇 |
内科学 | 489篇 |
皮肤病学 | 51篇 |
神经病学 | 340篇 |
特种医学 | 354篇 |
外科学 | 469篇 |
综合类 | 383篇 |
预防医学 | 221篇 |
眼科学 | 80篇 |
药学 | 160篇 |
1篇 | |
中国医学 | 17篇 |
肿瘤学 | 155篇 |
2023年 | 76篇 |
2022年 | 81篇 |
2021年 | 116篇 |
2020年 | 136篇 |
2019年 | 115篇 |
2018年 | 103篇 |
2017年 | 100篇 |
2016年 | 116篇 |
2015年 | 96篇 |
2014年 | 235篇 |
2013年 | 246篇 |
2012年 | 180篇 |
2011年 | 189篇 |
2010年 | 177篇 |
2009年 | 181篇 |
2008年 | 176篇 |
2007年 | 163篇 |
2006年 | 146篇 |
2005年 | 146篇 |
2004年 | 140篇 |
2003年 | 129篇 |
2002年 | 147篇 |
2001年 | 134篇 |
2000年 | 91篇 |
1999年 | 72篇 |
1998年 | 76篇 |
1997年 | 75篇 |
1996年 | 58篇 |
1995年 | 78篇 |
1994年 | 58篇 |
1993年 | 67篇 |
1992年 | 78篇 |
1991年 | 71篇 |
1990年 | 51篇 |
1989年 | 62篇 |
1988年 | 56篇 |
1987年 | 50篇 |
1986年 | 36篇 |
1985年 | 46篇 |
1984年 | 33篇 |
1983年 | 23篇 |
1982年 | 29篇 |
1981年 | 40篇 |
1980年 | 35篇 |
1979年 | 25篇 |
1978年 | 11篇 |
1977年 | 19篇 |
1976年 | 7篇 |
1974年 | 4篇 |
1971年 | 8篇 |
Introduction
Left ventricular (LV) dysfunction is estimated to occur in 10%–25% of the general intensive care unit (ICU) population and is frequently seen as regional wall motion abnormalities (RWMAs). Although RWMA is mostly attributed to myocardial ischemia or infarction, some studies have suggested that nonischemic RWMA might also be prevalent. We sought to establish that RWMA can be seen in critically ill patients with normal coronary arteries and to explore reasons for RWMA in this population.Methods
In this retrospective study, data from the hospital angiography register and the ICU register were collated between 2012 and 2019. Patients were identified who underwent angiography in conjunction with their ICU stay and had RWMA on echocardiography. Patients were divided into either those with non-obstructed or those with obstructed coronary arteries. Cardiac magnetic resonance imaging (cMRI) examinations were reviewed if they had been performed on patients with non-obstructed coronaries.Results
We identified 53 patients with RWMA and non-obstructed coronary arteries and 204 patients with RWMA and obstructed coronary arteries. Patients with non-obstructed coronary arteries were more often female, younger, and had fewer cardiovascular risk factors. They less commonly had ST elevation, but more frequently had T-wave inversion or serious arrhythmias. Troponin levels were higher in patients with obstructed coronary arteries, but NT-proBNP was similar between the groups. There were no differences in risk-adjusted 90-day mortality between patients with non-obstructed versus obstructed coronary arteries (OR 1.21, [95% CI 0.56–2.64], p = .628). In those with non-obstructed coronary arteries, follow-up echocardiography was available for 38 patients, of whom 30 showed normalization of cardiac function. Of the 14 patients with non-obstructed coronary arteries on whom cMRI was performed, 7 had a tentative diagnosis of Takotsubo syndrome or myocardial stunning; 4 had a myocardial infarction (preexisting in 3 cases); 1 patient had acute myocarditis; 1 patient had post-myocarditis; and 1 patient was diagnosed with dilated cardiomyopathy.Conclusion
RWMA can be seen to occur in critically ill patients in the absence of coronary artery obstruction. Several conditions can cause regional hypokinesia, and cMRI is useful to evaluate the underlying etiology. 相似文献Methods: In a prospective study, patients with AH underwent OCTA and FFA. AH graded as Grade 1 in 8 (optic disc, second order vessels visible), Grade 2 in 4 (optic disc, first-order vessels visible), Grade 3 in 11 (hazy view of optic disc) and Grade 4 (no view of fundus) in 2 eyes.
Results: A total of 20 patients (25 eyes) with AH were included. In comparison to FFA, OCTA was able to similarly detect Diabetic Retinopathy changes such as Neovascularization, microaneurysms, capillary dropout, and foveal avascular zone extent in vascular occlusion in all grades of AH.
Conclusion: OCTA, a noninvasive imaging tool, could detect various retinal vascular and macular abnormalities in patients with all grades of AH in comparison to FFA. 相似文献