Crosstalk Between Mucosal Inflammation and Bone Metabolism in Chronic Rhinosinusitis

Chronic rhinosinusitis (CRS) is a multifactorial and highly heterogeneous upper airway disease that affects approximately 12% of the general population. There is increasing evidence supporting the impact of osteitis on the pathophysiology of CRS. Osteitis is frequently observed in patients with CRS, and is associated with severe sinonasal inflammation and recalcitrant cases. The overlying inflammatory sinonasal mucosa plays a critical role in the initiation of osteitis; however, the underlying molecular mechanisms and functional significance remain unclear. Increasingly many studies have suggested that immune cells play a crucial role in the bone remodeling process in CRS. The purpose of this review is to summarize the current state of knowledge regarding the specific role of sinonasal inflammation in bone remodeling in CRS patients.     

儿童腺样体肥大与耳鼻咽喉科常见疾病关系的研究进展

腺样体肥大(AH)是小儿耳鼻咽喉科的常见病、多发病。国内外学者关于AH的病因、临床症状及治疗方式均有深入研究并达成共识,但其与耳鼻咽喉科相关疾病的关系仍未得到广泛关注和重视。研究发现,AH与小儿耳鼻咽喉科的过敏性鼻炎(AR)、急慢性鼻-鼻窦炎(ARS/CRS)、急性中耳炎、分泌性中耳炎、中耳胆脂瘤、急慢性扁桃体炎、扁桃体肥大、儿童阻塞性睡眠呼吸暂停综合征(OSAS)及其他咽喉部疾病等均有密切联系。     

鼻内镜术中不同中鼻甲处理方式治疗慢性鼻-鼻窦炎伴鼻息肉效果比较

探讨慢性鼻-鼻窦炎伴鼻息肉（CRSwNP）患者鼻内镜术中不同中鼻甲处理方式的临床效果。