全文获取类型
收费全文 | 28750篇 |
免费 | 2604篇 |
国内免费 | 514篇 |
专业分类
耳鼻咽喉 | 136篇 |
儿科学 | 614篇 |
妇产科学 | 475篇 |
基础医学 | 2679篇 |
口腔科学 | 417篇 |
临床医学 | 5603篇 |
内科学 | 2613篇 |
皮肤病学 | 90篇 |
神经病学 | 1962篇 |
特种医学 | 1266篇 |
外国民族医学 | 2篇 |
外科学 | 2169篇 |
综合类 | 3221篇 |
现状与发展 | 1篇 |
一般理论 | 2篇 |
预防医学 | 5333篇 |
眼科学 | 153篇 |
药学 | 3288篇 |
25篇 | |
中国医学 | 920篇 |
肿瘤学 | 899篇 |
出版年
2024年 | 20篇 |
2023年 | 555篇 |
2022年 | 701篇 |
2021年 | 1303篇 |
2020年 | 1419篇 |
2019年 | 1331篇 |
2018年 | 1252篇 |
2017年 | 1273篇 |
2016年 | 1232篇 |
2015年 | 1202篇 |
2014年 | 2051篇 |
2013年 | 2530篇 |
2012年 | 1875篇 |
2011年 | 1914篇 |
2010年 | 1535篇 |
2009年 | 1301篇 |
2008年 | 1432篇 |
2007年 | 1385篇 |
2006年 | 1153篇 |
2005年 | 909篇 |
2004年 | 749篇 |
2003年 | 648篇 |
2002年 | 526篇 |
2001年 | 416篇 |
2000年 | 410篇 |
1999年 | 351篇 |
1998年 | 247篇 |
1997年 | 246篇 |
1996年 | 174篇 |
1995年 | 212篇 |
1994年 | 183篇 |
1993年 | 150篇 |
1992年 | 146篇 |
1991年 | 115篇 |
1990年 | 94篇 |
1989年 | 89篇 |
1988年 | 99篇 |
1987年 | 87篇 |
1986年 | 70篇 |
1985年 | 89篇 |
1984年 | 84篇 |
1983年 | 57篇 |
1982年 | 58篇 |
1981年 | 35篇 |
1980年 | 29篇 |
1979年 | 46篇 |
1978年 | 24篇 |
1977年 | 14篇 |
1976年 | 17篇 |
1975年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
《The Journal of thoracic and cardiovascular surgery》2023,165(1):301-326
ObjectiveThe use of mechanical circulatory support (MCS) in lung transplantation has been steadily increasing over the prior decade, with evolving strategies for incorporating support in the preoperative, intraoperative, and postoperative settings. There is significant practice variability in the use of these techniques, however, and relatively limited data to help establish institutional protocols. The objective of the AATS Clinical Practice Standards Committee (CPSC) expert panel was to review the existing literature and establish recommendations about the use of MCS before, during, and after lung transplantation.MethodsThe AATS CPSC assembled an expert panel of 16 lung transplantation physicians who developed a consensus document of recommendations. The panel was broken into subgroups focused on preoperative, intraoperative, and postoperative support, and each subgroup performed a focused literature review. These subgroups formulated recommendation statements for each subtopic, which were evaluated by the entire group. The statements were then developed via discussion among the panel and refined until consensus was achieved on each statement.ResultsThe expert panel achieved consensus on 36 recommendations for how and when to use MCS in lung transplantation. These recommendations included the use of veno-venous extracorporeal membrane oxygenation (ECMO) as a bridging strategy in the preoperative setting, a preference for central veno-arterial ECMO over traditional cardiopulmonary bypass during the transplantation procedure, and the benefit of supporting selected patients with MCS postoperatively.ConclusionsAchieving optimal results in lung transplantation requires the use of a wide range of strategies. MCS provides an important mechanism for helping these critically ill patients through the peritransplantation period. Despite the complex nature of the decision making process in the treatment of these patients, the expert panel was able to achieve consensus on 36 recommendations. These recommendations should provide guidance for professionals involved in the care of end-stage lung disease patients considered for transplantation. 相似文献
2.
3.
4.
背景 人口老龄化趋势下,罹患多种慢性病的失能或半失能老年人对居家医疗护理服务需求迫切,但基层医务人员提供居家医疗护理服务存在较大的医疗风险和安全隐患,加强居家医疗护理服务的安全管理,有利于提高基层医务人员提供居家医疗护理服务的意愿。 目的 调查基层医疗卫生机构对居家护理服务的安全支持情况和医务人员的服务意愿,为进一步推动居家医疗护理服务发展提供参考依据。 方法 2021年8—10月,采用便利抽样法在四川省五大经济区抽取49所基层医疗卫生机构的1 131例医务人员。自行设计调查问卷,以"问卷星"电子问卷的形式收集资料。问卷内容包括医务人员的一般情况(8个条目)、提供居家医疗护理服务的经历(2个条目)、医疗机构对医务人员的安全支持(7个条目)、医务人员的居家医疗护理服务意愿(1个条目)。比较不同特征医务人员提供居家医疗护理服务的意愿,采用二元Logistic回归分析医务人员提供居家医疗护理服务意愿的影响因素。 结果 1 131例基层医务人员中,692例(61.18%)报告有过居家医疗护理服务的经历,193例(17.06%)报告在服务过程中发生过不良事件/安全事件,531例(46.95%)报告其所在医疗机构未评估过患者接受居家医疗护理服务的安全风险,199例(17.60%)表示所在机构评估了医务人员提供居家医疗护理服务的安全风险,299例(26.44%)在居家医疗护理服务过程中使用APP定位系统,273例(24.14%)由机构配备报警、延迟预警等设备,807例(71.35%)表示居家医疗护理服务过程中没有获得所在机构内其他医务人员的支持措施,303例(26.79%)表示机构曾组织居家医疗护理服务的专项研讨活动,352例(31.12%)表示接受过有关居家医疗护理服务专项培训,853例(75.42%)表示愿意提供居家医疗护理服务。二元Logistic回归分析结果显示,就职的基层医疗卫生机构类型,目前受聘的专业技术职称,医疗机构是否评估过患者接受居家医疗护理服务的安全风险,在居家医疗护理服务过程中是否配备报警、延迟预警等设备,是否参加过有关居家医疗护理服务的专项培训,对医务人员提供居家医疗护理服务意愿有影响(P<0.05)。 结论 现阶段居家医疗护理服务的安全支持不足,多种因素影响基层医务人员提供居家医疗护理服务的意愿。基层医疗卫生机构应加强对患者接受居家医疗护理服务安全风险的评估,为提供居家医疗护理服务的医务人员配备报警、延迟预警等设备,积极举办居家医疗护理服务相关的专项培训并鼓励医务人员参加,以降低医务人员提供居家医疗护理服务的风险,保障其人身安全。 相似文献
5.
6.
7.
目的 评价美国国家电器制造协会(National Electrical Manufactures Association, NEMA)最新标准(NU 2-2018)在正电子发射型计算机断层显像/电子计算机断层显像(positron emission tomography/computed tomography, PET/CT)设备性能检测中的作用。 方法 依据最新的NEMA NU 2-2018标准,检测西门子Biograph Vision PET/CT的空间分辨率、灵敏度、散射分数、计数丢失、随机符合、飞行时间分辨率、计数丢失率和随机符合校正精度、图像质量、衰减和散射校正精度及PET与CT配准精度指标。 结果 距视野中心1 cm处横向和轴向空间分辨率分别为3.75 mm和3.76 mm;在视野中心和轴向10 cm处的灵敏度分别为16.83 kcps/MBq和16.67 kcps/MBq;放射性浓度为27.37 kBq/mL时,最大等效噪声计数率为258.26 kcps,散射分数为38.58%;系统时间分辨率为209.82 ps;图像质量模型的对比度恢复系数范围为88.9%~96.2%,背景变异系数范围为2.05%~6.80%,平均肺插件残余误差为2.43%;计数丢失和随机符合校正最大误差为3.9%;距离床板末端 5 cm 和 100 cm处,在距视野中心Y轴1 cm处,PET和CT的配准精度分别为0.46 mm和1.07 mm,在距视野中心X轴20 cm处,PET和CT的配准精度分别为1.06 mm和1.45 mm,在距视野中心Y轴20 cm处PET和CT的配准精度分别为0.85 mm和1.15 mm。 结论 NEMA NU 2-2018标准检测条件更加接近临床,能更好地反映PET/CT设备的系统性能。 相似文献
8.
《Health & place》2022
PurposeAccording to the social determinants of health framework, income inequality is a potential risk factor for adverse mental health. However, few studies have explored the mechanisms suspected to mediate this relationship. The current study addresses this gap through a mediation analysis to determine if social support and community engagement act as mediators linking neighbourhood income inequality to maternal anxiety and depressive symptoms within a cohort of new mothers living in the City of Calgary, Canada.MethodsData collected at three years postpartum from mothers belonging to the All Our Families (AOF) cohort were used in the current study. Maternal data were collected between 2012 and 2015 and linked to neighbourhood socioeconomic data from the 2006 Canadian Census. Income inequality was measured using Gini coefficients derived from 2006 after-tax census data. Generalized structural equation models were used to quantify the associations between income inequality and mental health symptoms, and to assess the potential direct and indirect mediating effects of maternal social support and community engagement.ResultsIncome inequality was not significantly associated with higher depressive symptoms (β = 0.32, 95%CI = −0.067, 0.70), anxiety symptoms (β = 0.11, 95%CI = −0.39, 0.60), or lower social support. Income inequality was not associated with community engagement. For the depression models, higher social support was significantly associated with lower depressive symptoms (β = −0.13, 95%CI = −0.15, −0.097), while community engagement was not significantly associated with depressive symptoms (β = 0.059, 95%CI = −0.15, 0.27). Similarly, for the anxiety models, lower anxiety symptoms were significantly associated with higher levels of social support (β = −0.17, 95%CI = −0.20, −0.13) but not with higher levels of community engagement (β = 0.14, 95%CI = −0.14, 0.41).ConclusionThe current study did not find clear evidence for social support or community engagement mediating the relationship between neighbourhood income inequality and maternal mental health. Future investigations should employ a broader longitudinal approach to capture changes in income inequality, potential mediators, and mental health symptomatology over time. 相似文献
9.
Hannah C. Nordhues Anjali Bhagra Natya N. Stroud Jennifer A. Vencill Carol L. Kuhle 《Mayo Clinic proceedings. Mayo Clinic》2021,96(7):1907-1920
The coronavirus disease 2019 (COVID-19) pandemic has rapidly created widespread impacts on global health and the economy. Data suggest that women are less susceptible to severe illness. However, sex-disaggregated data are incomplete, leaving room for misinterpretation, and focusing only on biologic sex underestimates the gendered impact of the pandemic on women. This narrative review summarizes what is known about gender disparities during the COVID-19 pandemic and the economic, domestic, and health burdens along with overlapping vulnerabilities related to the pandemic. In addition, this review outlines recommended strategies that advocacy groups, community leaders, and policymakers should implement to mitigate the widening gender disparities related to COVID-19. 相似文献
10.
目的评价由丹娜(天津)生物科技股份有限公司生产的隐球菌荚膜多糖检测试剂盒(胶体金法,考核试剂)的检测性能。方法选取隐球菌和隐球菌近缘菌及肺部感染常见菌种共28属100株菌作为研究对象,配制0.5麦氏浊度单位(0.5 M)菌液检测试剂的特异性,0.5 M阳性的菌株以10倍倍比稀释液作为灵敏度检测菌液,以2 M和4 M浓度菌液作为钩状效应检测菌液,并以美国Immuno Mycologics公司生产的隐球菌抗原检测(胶体金免疫层析法)试剂盒作为对比试剂,比较两家试剂的一致性。结果31株隐球菌属菌株中,考核试剂检测出阳性25株(新型隐球菌和格特隐球菌均为阳性),阴性6株(维多利亚隐球菌、C.dimennae和大隐球菌);16株毛孢子菌属菌株中,检测出阳性12株,阴性4株;1株Cutaneotrichosporon curvatum检测结果为阳性;52株其他菌株的检测结果均为阴性;灵敏度实验结果显示考核试剂隐球菌最低检出限为1.0×102 CFU/mL;2 M和4 M浓度菌液均未出现钩状效应。结论考核试剂隐球菌荚膜多糖检测试剂盒(胶体金法)检测隐球菌属的灵敏度高于比对试剂;特异性方面存在一定的属内和属外交叉反应,但与对比试剂的检测结果高度一致;考核试剂与比对试剂均无钩状效应产生。 相似文献