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《Journal of cranio-maxillo-facial surgery》2022,50(9):686-691
The aim of the study was to compare automated and manually conducted (slice-by-slice) virtual orbital wall reconstruction in terms of PSI design, manufacture, and clinical application for orbital fracture management.Patients with orbital wall fractures were evaluated for the potential for treatment with PSI, based on automated virtual wall reconstruction; these formed the main group. The surgical outcomes of these main-group patients' treatments were compared with those of the control group, which comprised patients randomly selected for this study, each of whom had the same orbital trauma patterns and were also managed with PSI. However, the control group patients were treated using ‘slice-by-slice’ virtual orbital reconstruction.Mean volume differences between the intact and reconstructed orbit were 0.65 ± 0.26 cm3 in the main group (n = 23) and 0.57 ± 0.23 cm3 in the control (n = 27; p = 0.837). In both groups, no cases of implant malposition or enophthalmos were detected after surgery. Orbital shape difference was similar for the main group and the control, at ?3.3 ± 3.5% and 3.25 ± 2.5%, respectively (p = 0.929). Diplopia was diagnosed at the 3-month follow-up in 13.0% of the main group and in 11.1% of the control (p = 0.651). The average times spent on computer-aided design (CAD) procedures, including segmentation, virtual orbital reconstruction, and PSI design, were 36.7 ± 6.9 min in the main group and 72.9 ± 7.7 min in the control group (p < 0.001).Within the limitations of the study it seems that PSI based on automated virtual reconstruction is a relevant alternative treatment option for orbital fractures because of its clinical efficacy that is similar to PSI based on a ‘slice-by-slice’ CAD protocol. 相似文献
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《The Journal of thoracic and cardiovascular surgery》2023,165(2):634-644.e5
BackgroundProsthetic choice for mitral valve replacement is generally driven by patient age and patient and surgeon preference, and current guidelines do not discriminate between different etiologies of mitral valve disease. Our objective was to assess and compare short- and long-term outcomes after mitral valve replacement among patients with biological or mechanical prostheses in the setting of severe ischemic mitral regurgitation.MethodsBetween 2000 and 2016, 424 patients underwent mitral valve replacement for severe ischemic mitral regurgitation at our institution, using biological prosthesis in 188 (44%) and mechanical prosthesis in 236 (56%). A 1:1 propensity score match (n = 126 per group) and inverse probability of treatment weighting were used to compare groups. Short-term outcomes included in-hospital mortality and other cardiovascular adverse events. Long-term outcomes included survival and hospital readmission for cardiovascular causes, stroke, and major bleeding.ResultsIn-hospital mortality and early postoperative adverse events were similar between groups in the propensity score match and inverse probability of treatment weighting cohorts. Overall long-term survival was similar at 5 and 9 years, but mechanical prosthesis recipients were more frequently readmitted to hospital for cardiovascular causes, including stroke and non-neurological bleeding in propensity score matching and inverse probability of treatment weighting analyses (all P values < .004). Type of prosthesis did not independently influence all-cause mortality (hazard ratio, 1.01; 95% confidence interval, 0.71-1.43; P = .959), but placement of a mechanical prosthesis was associated with increased risk of readmission for cardiovascular events (hazard ratio, 1.65; 95% confidence interval, 1.17-2.32; P = .004) among matched patients.ConclusionsThe type of prosthesis has no influence on long-term survival among patients with severe ischemic mitral regurgitation undergoing mitral valve replacement. There may be an increased risk of neurologic events and serious bleeding associated with mechanical prostheses. 相似文献
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目的 应用锥形束CT(cone beam CT,CBCT)测量种植区牙槽骨质量并结合Lekholm和Zarb分类法对骨质量分类方法进行改良,以期为提高牙槽骨质量分类的准确性提供指导。方法 选择2015年10月至2017年10月在呼和浩特市口腔医院种植科进行种植修复的196例患者术前CBCT影像资料,应用 Invivo5诊断设计软件测量306个种植位点的牙槽骨皮质骨厚度和松质骨密度(皮质骨与松质骨的CT值差值),以Lekholm和Zarb分类法为基础结合测量数据对骨质量进行改良后的量化分类。结果 牙槽骨皮质骨厚度为0.18 ~ 2.89 mm,中位数为0.92 mm。皮质骨与松质骨的CT值差值为88.5 ~ 667.8 HU,应用百分位数法找到33.3%和66.6%对应的数值分别为297.8 HU和356.1 HU。依据此数据结合Lekholm和Zarb分类法将196例患者的306个种植位点骨质量分为4类,其中Ⅰ类骨种植位点46个(占15.0%),Ⅱ类骨104个(占34.0%),Ⅲ类骨114个(占37.3%),Ⅳ类骨42个(占13.7%)。结论 结合Lekholm和Zarb分类法,应用CBCT测量种植区牙槽骨质量并进行分类方法的改良,可为临床医生术前评估牙槽骨质量提供一定参考。 相似文献
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目的 研究上颌后牙区剩余牙槽骨高度为3 ~ < 4 mm时,行经牙槽嵴顶上颌窦底提升或侧壁开窗上颌窦底提升同期种植体植入的短期临床效果。方法 选择2016年1月至2018年12月于西安交通大学口腔医院种植科行经牙槽嵴顶上颌窦底提升和侧壁开窗上颌窦底提升同期种植体植入的患者45例(50侧上颌窦,上颌后牙区剩余牙槽骨高度为3 ~ < 4 mm),于术前、术后当日或术后第2天及术后6 ~ 9个月的愈合期后行影像学检查,比较两种术式的上颌窦底新骨形成高度、上颌窦底黏膜穿孔率及种植体早期成功率。结果 采用经牙槽嵴顶上颌窦底提升或侧壁开窗上颌窦底提升同期种植体植入的分别有19例和26例(上颌窦分别为21、29侧)患者;上颌窦底黏膜穿孔率分别为4.76%和0,差异无统计学意义(P > 0.05)。经过6 ~ 9个月的愈合期,两种术式上颌窦底新骨形成高度分别为(5.18 ± 0.48)mm和(7.32 ± 0.84)mm,差异有统计学意义(P < 0.05);两种术式种植体早期成功率分别为95.83%和100%,差异无统计学意义(P > 0.05)。结论 当上颌后牙区剩余牙槽骨高度为3 ~ < 4 mm时,两种术式均安全可靠,早期成功率高。 相似文献
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目的研究快速成型(RP)技术辅助下制作的个体化假体复合珊瑚羟基磷灰石(CHA)、重组人骨形成蛋白2(rhBMP-2)修复兔下颌骨缺损的成骨效果。
方法以27只新西兰大白兔为实验对象,随机数字表法平均分成3组(每组9只),全部建立下颌骨连续性缺损模型,并在兔下颌骨缺损区分别植入个体化假体+自体骨(A组)、个体化假体+CHA(B组)、个体化假体+CHA+rhBMP-2(C组)。分别于术后4、12、24周3个时间点处死动物取材,进行大体标本观察,以及骨钙素(OC)、Ⅰ型胶原(COL-1)的免疫组化观察,分别比较各组修复骨缺损的能力,并对实验数据进行重复测量设计资料的单因素方差分析。
结果术后24周各组实验兔外形均对称,通过OC及COL-1的吸光度检测,骨缺损区均有大量新骨形成,A组(0.537 ± 0.010)、C组(0.530 ± 0.010)可见大量骨小梁及编织骨结构,缺损区的新骨OC、COL-1的免疫组化观察基本一致,差异无统计学意义(t = 0.007,P>0.05);但A组强于B组(0.415 ± 0.009,t = 0.122,P<0.001);C组也强于B组(t = 0.121,P<0.001),差异均有统计学意义。
结论在兔下颌骨缺损修复中,通过RP技术和组织工程技术相结合,CHA复合rhBMP-2后成骨能力明显增强,成骨效能肯定,为后期的临床应用提供可靠的实验基础。 相似文献