多层螺旋CT对急性阑尾炎的诊断价值

目的探讨多层螺旋CT（MSCT）对急性阑尾炎的诊断价值。方法收集临床疑诊和／或经手术和病理证实为急性阑尾炎患者35例，回顾分析其CT表现。结果26例确诊急性阑尾炎病例中主要CT征象有：阑尾肿大24例（92％），阑尾粪石10例（38％），回盲部肥厚12例（46％），阑尾周围炎20例（77％），局限性脓肿2例（8％）。对照手术病理，MSCT诊断急性阑尾炎准确率89％、敏感性92％、特异度74％、阳性预测值92％、阴性预测值71％。结论MSCT显著提高了急性阑尾炎的术前诊断能力，应成为临床首选的影像学检查方法。     

The cost effectiveness of early management of acute appendicitis underlies the importance of curative surgical services to a primary healthcare programme

Introduction

Appendicitis in the developing world is a cause of significant preventable morbidity. This prospective study from a regional hospital in South Africa constructs a robust cost model that demonstrates the cost effectiveness of an efficient curative surgical service in a primary healthcare-orientated system.

Methods

A prospective audit of all patients with acute appendicitis admitted to Edendale Hospital was undertaken from September 2010 to September 2011. A microcosting approach was used to construct a cost model based on the estimated cost of operative and perioperative interventions together with the associated hospital stay. For cost analysis, patients were divided into the following cohorts: uncomplicated appendicitis, complicated appendicitis with localised intra-abdominal sepsis, complicated appendicitis with generalised intra-abdominal sepsis, with and without intensive care unit admission.

Results

Two hundred patients were operated on for acute appendicitis. Of these, 36% (71/200) had uncomplicated appendicitis and 57% (114/200) had perforation. Pathologies other than appendicitis were present in 8% (15/200) and these patients were excluded. Of the perforated appendices, 45% (51/114) had intra-abdominal contamination that was localised while 55% (63/114) generalised sepsis. The mean cost for each patient was: 6,578 ZAR (£566) for uncomplicated appendicitis; 14,791 ZAR (£1,272) for perforation with localised intra-abdominal sepsis and 34,773 ZAR (£2,990) for perforation with generalised intra-abdominal sepsis without intensive care admission. With intensive care admission it was 77,816 ZAR (£6,692). The total cost of managing acute appendicitis was 4,272,871 ZAR (£367,467). Almost 90% of this total cost was owing to advanced disease with abdominal sepsis and therefore potentially preventable.

Conclusions

Early uncomplicated appendicitis treated appropriately carries little morbidity and is relatively inexpensive to treat. As the pathology progresses, the cost rises exponentially. An efficient curative surgical service must be regarded as a cost effective component of a primary healthcare orientated system.     

Inflammatory Myofibroblasts Tumour (IMT) of the Liver: A Report of Two Cases

Inflammatory myofibroblastic tumour (IMT) is an uncommon mass lesion composed of myofibroblasts and mixed inflammatory infiltrate that rarely undergoes malignant transformation. Although IMT was originally reported in the lung, it is now recognised that it can occur in a variety of organs. Hepatic localisation of IMT is less frequent. Here we report two cases of IMT in the liver. They underwent hepatic resections with the diagnosis of FNH and Klatskin tumour. The pathological diagnosis of the tumour was IMT. We conclude that in the management of IMT in the liver, surgical excision is the primary choice, in order to obtain a definitive diagnosis as well as to relieve symptoms, and strict follow-up after surgery is required for the timely detection of recurrence.     

Laparoscopy utilization and outcomes for appendicitis in small children

Purpose

To examine the trends in laparoscopic appendectomy (LA) utilization and outcomes for children 5 years or younger.

Methods

We studied 16,028 inpatient admissions for children 5 years of age or less undergoing an appendectomy for acute appendicitis in 2000, 2003, and 2006 using the Kids' Inpatient Database (KID). Laparoscopy frequency, hospital length of stay, and complications were reviewed.

Results

In 2000, 2003 and 2006 appendectomies were done laparoscopically 11.4%, 18.7% and 31.3% of the time, respectively. Children were more likely to undergo LA at a children's hospital (P < 0.001). LA complications were less likely overall (OR: 0.80, CI: 0.70–0.92, P = 0.002) and in perforated cases (OR: 0.78, CI: 0.67-0.91, P = 0.001). LA decreased hospital length of stay by 0.54 days for all patients and 0.70 days for perforated cases (P < 0.001).

Conclusions

Open appendectomy has historically been the standard in children 5 years of age and younger. Laparoscopic appendectomy has slowly gained acceptance for the treatment of appendicitis in smaller children. The use of laparoscopy has increased significantly at all facilities. Furthermore, laparoscopic appendectomy in this age group has a comparatively low complication rate and short hospital length of stay, and is safe in complicated perforated appendicitis cases.     

Appropriate use of total parenteral nutrition in children with perforated appendicitis

Background

Total parenteral nutrition (TPN) is often used in children with perforated appendicitis, despite the absence of clear indications. We assessed the validity of specific clinical indications for initiation of TPN in this patient cohort.

Outcome of initially nonoperative treatment for acute simple appendicitis in children

Purpose

To compare the outcome of initially nonoperative treatment with immediate appendectomy for simple appendicitis in children.

急性阑尾炎B型超声、MSCT检查影像学表现及临床诊治价值对比

目的分析急性阑尾炎B型超声、MSCT检查影像学表现及临床诊治价值。方法选取本院2017年7月至2019年8月收治的急性阑尾炎患者87例的临床资料作为研究对象,均经术后病理检查证实。所有患者均进行B型超声、MSCT检查。其中急性单纯性阑尾炎38例,急性化脓性阑尾炎21例,坏疽性阑尾炎11例,阑尾周围囊肿17例。分析B型超声、MSCT图像进行分析,计算B型超声、MSCT对急性阑尾炎诊断准确率。结果MSCT对急性单纯性阑尾炎、急性化脓性阑尾炎、坏疽性阑尾炎、阑尾周围囊肿诊断镇正确率上明显高于B型超声检出率(P<0.05)。B型超声表现:可见患者病变处为不可压缩腊肠样结构,壁增厚或没有明显的壁增厚但管腔扩张,周围脂肪回声增强。MSCT表现:阑尾直径增粗(>6mm),管壁增厚、可见粪石、脓肿/肿块、阑尾腔积液/积气,增强后阑尾壁强化。结论B型超声、MSCT检查对急性阑尾炎均有一定的诊断价值,B型超声检查快捷、方便、重复性高,在急性阑尾炎早期筛查中适用性高,对于不能明确诊断者可进一步行MSCT检查确诊。     

Sonography of ruptured appendicitis

Three girls and 4 boys with the final diagnosis of ruptured appendicitis underwent 19 sonographic studies, 5 before any therapy was instituted and 14 follow-up studies. Four abscesses identified before treatment and 2 seen postoperatively were ovoid, irregularly marginated, and contained lowamplitude echoes. Gastrointestinal ileus with gas- and fluid-filled loops of bowel made the studies technically difficult. Follow-up studies also showed fluid collections distant from the original abscesses. The complete resolution of the abscess was followed sonographically in 1 patient treated with antibiotics. Ultrasound can be useful in confirming or suggesting the diagnosis of ruptured appendicitis in the child with abdominal pain, but careful attention to detail is necessary in these technically difficult studies.     

Is Laparoscopic Appendectomy an Effective Procedure ?

Aim: To compare the results of open and laparoscopic appendectomy and to determine if the laparoscopic approach might be more effective for some subgroups of patients.

Material and methods: We retrospectively analysed the computerised data of 326 consecutive adult patients operated on for suspected appendicitis between 2001 and 2005. The series consisted of 166 men and 160 women with a mean age of 32 ± 16 years and a mean Body Mass Index (BMI) of 24 ± 4. There were 265 ASA I, 46 ASA II and 5 ASA III patients. According to the surgeon’s preference, 176 patients had an open appendectomy (OA) and 150 a laparoscopic appendectomy (LA).

Results: The mean operative time and hospital stay were equivalent in the two groups: respectively 49 ± 19 min. and 4.1 ± 2.5 days in OA and 50 ± 16 min. and 3.5 ± 1.8 days in LA. However, subgroup analysis revealed that overweight (BMI > 25) patients (n=102) and patients with ectopic appendices (n=86) had an obvious benefit from LA. In cases of OA, operative time and hospital stay were longer in overweight patients than in normal weight patients: respectively 63 ± 20 min. and 5.3 ± 2.9 days versus 44 ± 16 min. (p < 0.01) and 3.7 ± 2.2 days (p < 0.01). On the contrary, no difference was observed in the lA group. Operative time and hospital stay were also longer in patients with ectopic appendices submitted to OA than in patients with an appendix in the normal position: respectively 60 ± 18 min. and 4.7 ± 2.7 days versus 45 ± 18 min. (p < 0.01) and 3.9 ± 2.4 days (p < 0.01). Again, such a difference was not observed in cases of LA. We noted no mortality, but 24 patients (7%) developed an abdominal complication: 18 wound infections and 6 intra-abdominal abscesses. Wound infections were more common in the OA than in the LA group: 7.3% (13/176) versus 3.3% (5/150) (p = 0.1). In the LA group, 4 wound infections were observed in our early experience, at a time where no endoscopic bag was used for the removal of the appendix. The rate of intra-abdominal abscesses was similar: 1.7% (3/176) in the OA group and 2% (3/150) in the LA group.

Conclusions: LA is an effective procedure with a reduced risk of developing wound infection. The laparoscopic approach is particularly effective for overweight patients and/or patients with ectopic appendices as far as shortening the operative time and hospital stay are concerned.     

穿孔性阑尾炎与非穿孔性阑尾炎的CT鉴别诊断

目的:评价多排螺旋CT对穿孔性与非穿孔性阑尾炎的鉴别诊断价值.方法:搜集手术及病理证实的急性阑尾炎151例,并按照手术及病理结果分为穿孔组(66例)和非穿孔组(85例),总结分析其CT表现,并比较穿孔性与非穿孔性阑尾炎的CT表现.结果:阑尾腔外粪石、阑尾腔外气体、阑尾周围脓肿、阑尾壁局限性强化缺损对诊断阑尾炎穿孔有很高的特异性(P＜0.05),为诊断阑尾炎穿孔的特异性征象;阑尾周围炎、盆腔炎改变在穿孔组发现频率也明显高于非穿孔组(P＜0.05),穿孔组阑尾直径明显大于非穿孔组(P＜0.05),对诊断阑尾炎穿孔有一定价值;阑尾位置、阑尾腔内粪石、阑尾腔内气体、阑尾周围淋巴结肿大在两组中无明显差异(P＞0.05).结论:CT是诊断穿孔性阑尾炎有效、快速的方法,其中阑尾腔外粪石、阑尾腔外气体、阑尾壁局限性强化缺损、阑尾周围脓肿为诊断穿孔性阑尾炎较为特异的CT征象,阑尾周围炎、盆腔炎改变、阑尾直径增大对于诊断阑尾炎穿孔有一定价值.