中西医结合治疗不孕症80例临床分析

中西医结合治疗不孕症８０例临床分析上海第二医科大学附属仁济医院妇产科汤希伟上海闸北区新疆路地段医院蒋来娣１９８６年６月到１９８８年１２月，作者以中药为主、中西医结合诊治的门诊病员，收集资料完整的８０例女性不孕症患者，予以临床分析。其中原发不孕５７例，...     

皮瓣转移治疗手部皮肤脱套伤

我科1985年12月～1988年12月,应用皮瓣转移治疗手部皮肤套状撕脱伤8例,男5例,女3例,年龄19～30岁。5指脱套包括部分掌背侧皮肤撕脱2例,2～5指脱套伤4例,3指脱套伤2例,伤后距手术时间最短2小时,最长23小时,采用     

胃结肠癌性激素受体状态的临床实验研究

本文对１６０例胃结肠癌与非癌组织学标本的性激素受体检测结果显示：性激素受体不同程度的存在于癌与非癌组织内；ＥＲ阳性率５０岁以上为７３．９％，无性别差异；ＰＲ、ＡＲ阳性率受性别及年龄的影响；组织学类型影响性激素受体分布；癌与非癌对照有显著差异（Ｐ＜０．０１）。     

掌背动脉蒂逆行掌骨瓣移位治疗指骨骨折不连接

为设计以掌背动脉为蒂的逆行掌骨瓣移位，对１２侧新鲜成人上肢标本进行解剖观察，发现手的掌背动脉在指蹼处与指革侧总动脉有恒定的吻合支．并发出１～３条小分支至２～５掌骨基底部．临床应用掌背动脉蒂逆行掌骨瓣移位治疗指骨骨折不连接６例，掌骨瓣最大１．２ｃｍ×０．５ｃｍ×０．５ｃｍ，最小０．７ｃｍ×０．５ｃｍ×０．５ｃｍ。指骨均在２．５～３个月内骨性愈合，经术后８～１０个月随访，按ＴＡＭ标准评价，关节功能恢复优良率达８０％．本术式提供有血运的活骨，加速骨折愈合，为治疗指骨骨折不连接提供了一个好的手术方法．     

雄黄酊治疗带状疱疹38例

目的探讨雄黄酊治疗带状疱疹的疗效。方法用雄黄和75%乙醇调成糊状外敷于带状疱疹处。结果38例带状疱疹全部痊愈。结论雄黄酊治疹带状疱疗方法简单,效果好,经济实惠。     

力达霉素对神经胶质瘤细胞血管生成拟态的抑制及对细胞凋亡的影响

Objective To evaluate the in vitro effects of lidamycin upon vasculogenic mimicry and apoptosis induction in glioma cells. Methods Tube formation assay was performed to estimate the inhibitory effects of lidamycin upon vasculogenic mimicry in C6 and U87 glioma cells. The vasculogenic mimicry of glioma cells was photographed and enumerated. Annexin V-FITC/PI was used for determination of glioma cell apoptosis with flow cytometry. Results Vasculogenic mimicry assay indicated that 0. 1 nmol/L, 0. 5 nmol/L and 1 nmol/L lidamycin showed significant inhibition of vasculogenic mimicry in C6 and U87 cells. Comparing with C6 control group (14. 7 ± 1.2), 0. 1 nmol/L (12. 7 ± 0. 6), 0. 5 nmol/L (9. 0 ± 1.7) and 1 nmol/L (4. 7 ± 0. 6) lidamycin inhibited vasculogenic mimicry in C6 cells with statistical significances (P = 0. 013, P = 0. 005 and P = 0. 0002 respectively). Comparing with U87 control group (14.7±1.2), the vasculogenic mimicry of 0.1 nmol/L (10.0±2.0), 0.5 nmol/L (8.3±1.5) and 1 nmol/L lidamycin (4. 3±0. 6) treated U87 cells showed statistical significances (P =0. 025, P =0. 005 and P =0. 0009 respectively). The apoptotic ratios of same dosages lidamycin treated C6 cells and U87 cells showed a similar tendency as vaaculogenic mimicry inhibition (P < 0. 001). Lidamycin was more potent than neocarzinostatin in vasculogenic mimicry inhibition and apoptosis induction of C6 cells and U87 cells. Conclusion Lidamycin can inhibit vasculogenic mimicry and promote apotosis of glioma cells. Thus it is a promising drug in glioma treatment. Further researches on the therapeutic efficacy of enediyne antibiotics in glioma are needed.     

均匀设计在L-亮氨酸发酵中的应用

<正> 均匀设计是一种新的试验方法,它适用于多因素、多水平的实验设计。这一方法在其他领域的优化处理上已取得一些成果,而在微生物发酵条件考查方面尚无报道。本实验则是采用这一方法进行了L-亮氨酸发酵条件的考查。     

恶性疟原虫RNA组分的分离

恶性疟原虫ＲＮＡ组分的分离南京军区福州总医院检验中心第一军医大学疟疾免疫研究室福州３５０００１兰风华，林来兴妹，赵雨田，毕惠祥，彭一兵，李英杰为了研究恶性疟原虫的ＲＮＡ，综合文献报道的多种方法，建立了从同批虫体中分离多个不同ＲＮＡ组分的方法，效果良好...