A cross-sectional assessment of oxidative DNA damage and muscle strength among elderly people living in the community

Objectives

The mechanism by which muscle weakness leads to an increased risk of death remains a subject of interest. In this context, the aim of this study is to assess the relationship between urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) and muscle strength, and other risk factors contributing to poor muscle strength in older persons.

Methods

This was a cross-sectional study in which a total of 86 participants, both men and women, aged 65 years or above were screened for urinary 8-OHdG, and muscle strength as measured by handgrip strength.

Results

Handgrip strength was lower in participants who had history of acute or chronic disease. Urinary 8-OHdG level was negatively associated with muscle strength, and the association remained after adjusting for confounding factors.

Conclusions

Urinary 8-OHdG is associated with muscle strength. These findings may be clinically relevant as there is a possibility of controlling oxidative DNA damage by healthy behaviors related to lifestyle.     

艾滋病检测咨询数量保证新模式研究

目的探讨建立艾滋病检测咨询数量保证新模式,提高检测数量,扩大监测检测覆盖面,及早、更多发现艾滋病病毒感染者。方法在政府的统一领导下,扩大宣传教育覆盖面,营造良好社会氛围。组织协调相关部门统一开展工作,建立艾滋病检测咨询数量保证新模式。并对2012年度（原模式）和2013年度（新模式）的艾滋病检测咨询数量相对照。结果二者结果有统计学意义（χ2=154,P=0.007〈0.05）。结论艾滋病检测咨询数量保证新模式能够提高检测数量,扩大监测检测覆盖面。     

Does the practice of sports or recreational activities improve the balance and gait of children and adolescents with sensorineural hearing loss? A systematic review

BackgroundBalance and gait disorders have been observed in children and adolescents with sensorineural hearing loss (SNHL), justified by vestibular dysfunctions that these children may present, due to the injury to the inner ear. Therefore, some investigations have suggested that the practice of sports or recreational activities can improve the balance and gait of this population.ObjectiveAssess the evidence quality from randomized or quasi-randomized controlled trials that used sports or recreational activities as an intervention to improve the balance and /or gait of children and/or adolescents with SNHL.MethodsSystematic review that surveyed articles in nine databases, published up to January 10, 2019, in any language, using the following inclusion criteria: (1) Randomized or quasi-randomized controlled trials. (2) Participants from both groups with the clinical diagnosis of SNHL, aged 6–19 years old, without physical problems, cognitive or neurological deficits, except the vestibular dysfunction. (3) Using the practice of sports or recreational activities as an intervention, to improve the balance and/or gait outcomes.Results4732 articles were identified in the searches, after the removal of the duplicates articles and the reading of the titles and their abstracts, remained 16 articles for reading in full, being 5 trials eligible for this systematic review. Of the five eligible trials, three used sports activities and two recreational activities as intervention and presented very low-quality evidence for balance and gait outcomes.SignificanceSports and recreational practices seem to represent promising modalities to improve the balance and gait of children and adolescents with SNHL. However, due to the methodological limitations of the trials and the low quality of the current evidence on the topic, the results of the trials should be interpreted with caution. Due to the low quality of evidence observed, we suggest that new trials be proposed on this topic, with greater methodological rigor, to provide high-quality evidence on the effectiveness of sports and recreational practices to improve the balance and gait of children and adolescents with SNHL.     

Utilisation des services d’aide et de soins à domicile pour les personnes âgées en situations complexes : comparaison entre trois types de coordination gérontologique

BackgroundOlder people with complex needs live mainly at home. Several types of gerontological coordinations have been established on the French territory to meet their needs and to implement social and primary health care services. But we do not have any information on the use of these services at home as a function of the coordination method used.MethodsWe compared the use of home care services for older people with complex needs in three types of coordination with 12 months’ follow-up. The three coordinations regrouped a gerontological network with case management (n = 105 persons), a nursing home service (SSIAD) with a nurse coordination (n = 206 persons) and an informal coordination with a non-professional caregiver (n = 117 persons).ResultsAt t0, the older people addressed to the gerontological network had less access to the services offered at home; those followed by the SSIAD had the highest number of services and of weekly interventions. Hours of weekly services were two-fold higher in those with the informal coordination. At t12, there was an improvement in access to services for the network group with case management and an overall increase in the use of professional services at home with no significant difference between the three groups.ConclusionThe use of social and primary health care services showed differences between the three gerontological coordinations. The one-year evolution in the use of home services was comparable between the groups without an explosion in the number of services in the network group with case management.     

重性精神病患者封闭式住院治疗期间心理需求分析

目的了解封闭式管理重性精神病患者住院治疗期间心理需求。方法采用便利抽样法,2017年3月—2018年3月选取四川省精神卫生中心封闭式管理的81例重性精神病患者为研究对象,采用自行设计的重症精神病患者心理需求调查问卷进行调查,调查患者自知力、住院治疗自我归因、希望解决的问题等心理需求状况,分析患者心理需求的影响因素。结果81例患者中33.33%(27/81)的患者认为自己患病,对于本次住院治疗39.51%(32/81)的患者归因于自己性格原因,归因于情感问题占17.28%(14/81);心理需求中,希望有家人的陪伴和探视占79.01%(64/81),有心理治疗需求占62.96%(51/81);最想解决的问题中,35.80%(29/81)的患者希望治好疾病,需要提高自信心的患者只占4.94%(4/81)。不同疾病诊断的患者在希望家人陪伴和探视的需求中差异有统计学意义(P<0.05)。不同性别患者在自身疾病相关知识的需求中差异有统计学意义(P<0.05)。不同文化程度的患者对提升压力应对能力需求的差异有统计学意义(P<0.05)。结论封闭式管理重性精神病患者住院治疗期间有较多心理需求,不同性别、文化程度、疾病诊断患者的需求不同,要有针对性地提供心理干预及护理,促进患者尽快康复。     

Psychoanalytic Failure

The portrayal of psychoanalysts in films and on television is usually a far cry from being a realistic depiction. As professional consultant to a TV series, I initially believed that my task was to uphold the public reputation of analysts; but, as I became further involved, I realized that the shortcomings and failures of analysts are essential to good drama. Films do not attempt to represent the actual reality accurately but rather to convey an inner reality. The analyst as protagonist becomes a far more interesting character once we observe him dealing with his conflicts, weaknesses, and limitations. Filmmakers attempt to allow for our authenticity and humanity and permit the analyst to enact well beyond what may be considered acceptable, not because they want to denigrate him but rather to show the fragile human being behind the professional. My role as consultant was to try to assure accuracy in the depiction of the analyst's work and at the same time to allow the drama to reach those dangerous and dark places that our work does not ordinarily traverse but that nevertheless represent our deepest wishes and anxieties.