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21.
22.
儿童感觉统合失调及其影响因素的调查分析 总被引:17,自引:1,他引:16
目的 研究儿童感觉统合失调与学习障碍及环境因素的关系。方法 采用感觉统合评定量表和学习障碍(PRS)筛查量表,分别对755名学龄儿童进行检测、分析。结果 感觉统合严重失调率为13.25%;感觉统合正常与失调儿童的学习障碍有统计学差异(P<0.005);其中在LD儿童中感觉统合失调率占63.51%;感觉统合失调与母孕期的情绪、是否足月顺产、出生后的喂养方式、居住环境、孩子1岁内有无高热、家长对孩子的态度及期待等因素有关(P<0.05)。结论 儿童感觉统合失调与环境因素、学习障碍有一定的关系。 相似文献
23.
王佑三 《山东中医药大学学报》1990,(4)
《明天的医学向何处去》一文是王佑三同志应中国中医研究院、中西医结合研究会1990~2010年中医药研究的重大进展与突破预测研究课题组和中国人体科学学会之约所撰。本报征得作者同意稍加删节后发表,期望引起对“明天的医学”的关注。 相似文献
24.
Toshio Mizutani Ken-ichi Nakamura Mutsuo Enomoto Masuhiro Sakata Shigeo Yamada 《Neuropathology》1998,18(1):80-90
A neuropathological study on 1540 consecutive autopsy brains ranging from 60 to 107 years of age revealed the following points. (1) Of the of the demented cases of the plaque-predominant type, 93% were complicated with multiple tiny cortical infarcts. They showed a tendency for dementia to develop before or after the appearance or worsening of a systemic disorder such as cardiovascular disease, respiratory infection and cancer. However, there was no case showing Alzheimer-type dementia (ATD). (2) The plaque-predominant type might be an extreme condition of brain aging in terms of senile plaques (SP). It is likely that although the pathological appearance of SP alone is not responsible for dementia, its coexistence with multiple cortical infarcts could be the cause of dementia. Therefore, this type should be distinguished from ATD. (3) Primary hippocampal degeneration could also be an extreme condition of brain aging in terms of neurofibrillary tangles. This condition was different pathologically from the hippocampal lesion in ATD. (4) Several characteristics of old-old and oldest-old patients were clarified. 相似文献
25.
住房类型、环境与居民健康协作研究之四——住房类型、环境与第二代成人健康 总被引:1,自引:0,他引:1
本文报告了北京市西城区三种类型住房三代同堂家庭调查样本125户中第二代成人199人的问卷调查结果。调查结果显示三种类型住房第二代成人的健康状况及烟酒嗜好差别无显著性;楼房的居住环境优于平房,但邻里交往不如平房密切;对居住条件和生活的自我评价主要取决于住房设施,邻里关系、年龄和性别,而受住房类型影响较小。 相似文献
26.
F. Schenk B. Contant P. Werffeli 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1990,82(3):641-650
Summary Age-related cognitive impairments were studied in rats kept in semi-enriched conditions during their whole life, and tested during ontogeny and adult life in various classical spatial tasks. In addition, the effect of intrahippocampal grafts of fetal septal-diagonal band tissue, rich in cholinergic neurons, was studied in some of these subjects. The rats received bilateral cell suspensions when aged 23–24 months. Starting 4 weeks after grafting, they were trained during 5 weeks in an 8-arm maze made of connected plexiglass tunnels. No age-related impairment was detected during the first eight trials, when the maze shape was that of a classical radial maze in which the rats had already been trained when young. The older rats were impaired when the task was made more difficult by rendering two arms parallel to each other. They developed an important neglect of one of the parallel tunnels resulting in a high amount of errors before completion of the task. In addition, the old rats developed a systematic response pattern of visits to adjacent arms in a sequence, which was not observed in the younger subjects. None of these behaviours were observed in the old rats with a septal transplant. Sixteen weeks after grafting, another experiment was conducted in a homing hole board task. Rats were allowed to escape from a large circular arena through one hole out of many, and to reach home via a flexible tube under the table. The escape hole was at a fixed position according to distant room cues, and olfactory cues were made irrelevant by rotating the table between the trials. An additional cue was placed on the escape position. No age-related difference in escape was observed during training. During a probe trial with no hole connected and no proximal cue present, the old untreated rats were less clearly focussed on the training sector than were either the younger or the grafted old subjects. Taken together, these experiments indicate that enriched housing conditions and spatial training during adult life do not protect against all age-related deterioration in spatial ability. However, it might be that the considerable improvement observed in the grafted subjects results from an interaction between the graft treatment and the housing conditions. 相似文献
27.
Aoyama K Ozaki Y Nakanishi T Ogasawara MS Ikuta K Aoki K Blomgren K Suzumori K 《American journal of reproductive immunology (New York, N.Y. : 1989)》2004,52(6):362-369
PROBLEM: The distribution and activation of mu-calpain and possible cleavage of integrin in human endometrial cells under hypoxic condition were investigated. METHOD OF STUDY: Human endometrial epithelial and stromal cells were subjected to hypoxia, and subsequently used for immunostaining and western blot analysis. RESULTS: The proform of mu-calpain was detected in the cytoplasm of normal cells, and displayed a substantial decrease after hypoxia. Conversely, the active form of mu-calpain was not detected in normal cells, but was abundant after hypoxia. The cytoplasmic domain of integrin beta3 was also detected in the cytoplasm of endometrial cells. Western blot analysis confirmed that both the proform of mu-calpain and the integrin beta3 cytoplasmic domain decreased during hypoxia. CONCLUSIONS: Mu-calpain is activated in human endometrial cells during hypoxia and that subsequent cleavage of the integrin beta3 cytoplasmic domain may give some adverse effects to the function of human endometrium. 相似文献
28.
We examined the effects of early rearing experience on the development of dominance status in 53 juvenile (age 3) and then in 38 adult (ages 5-8) rhesus macaques. Based on previous research investigating the behavioral outcomes of nursery-rearing, we predicted that mother-reared (MR) monkeys would outrank peer-only reared (PR) monkeys, which would in turn outrank surrogate/peer-reared (SPR) subjects. Juvenile MR and PR subjects did not differ in ranks, but monkeys from both rearing backgrounds outranked SPR cage-mates at age 3. Independent of rearing condition, high-ranking juveniles gained the most weight between ages 1-3, suggesting that low status may be associated with decreases in early weight gain. Adult MR subjects outranked both PR and SPR subjects, with PR animals occupying intermediate ranks. These results indicate that impoverished early experiences, such as adult absence and limited social interaction, are useful predictors of future social success in rhesus macaques. 相似文献
29.
30.
J. G. Villa G. Cuadrado J. E. Bayón J. González-Gallego 《European journal of applied physiology》1997,77(1-2):106-111
The effects of physical conditioning on antipyrine clearance were studied in two groups of subjects. Healthy men not engaged
in the systematic practice of any sport were compared with endurance runners (defined as men running >80 km/week). Studies
were carried out at three different periods of the annual plan training at 4-month intervals. Antipyrine was administered
orally and pharmacokinetic parameters were obtained from saliva samples by the multiple-sample method. Endurance performance,
expressed in terms of the maximal oxygen uptake (V˙O2
max), the ventilatory threshold and the 4-mM · l−1 lactate threshold (OBLA), was higher in trained than in control subjects at each of the three periods. Antipyrine clearance
was also significantly elevated and antipyrine half-life reduced in runners during all periods. No significant difference
in V˙O2
max or antipyrine clearance was found between the various periods in either trained or control subjects. Both ventilatory threshold
and OBLA increased significantly along the training period in conditioned subjects. Significant correlations were found between
antipyrine clearance and V˙O2
max, ventilatory threshold and OBLA. In summary, these results indicate an association between aerobic conditioning and increased
hepatic oxidative metabolism of low-clearance drugs.
Accepted: 15 July 1997 相似文献