全文获取类型
收费全文 | 153339篇 |
免费 | 12152篇 |
国内免费 | 3998篇 |
专业分类
耳鼻咽喉 | 1052篇 |
儿科学 | 2856篇 |
妇产科学 | 1974篇 |
基础医学 | 8283篇 |
口腔科学 | 3035篇 |
临床医学 | 21826篇 |
内科学 | 25092篇 |
皮肤病学 | 2412篇 |
神经病学 | 7890篇 |
特种医学 | 4582篇 |
外国民族医学 | 42篇 |
外科学 | 13222篇 |
综合类 | 23048篇 |
现状与发展 | 23篇 |
一般理论 | 2篇 |
预防医学 | 9279篇 |
眼科学 | 2080篇 |
药学 | 12960篇 |
179篇 | |
中国医学 | 11863篇 |
肿瘤学 | 17789篇 |
出版年
2024年 | 237篇 |
2023年 | 2792篇 |
2022年 | 4023篇 |
2021年 | 7087篇 |
2020年 | 6703篇 |
2019年 | 5807篇 |
2018年 | 5526篇 |
2017年 | 6085篇 |
2016年 | 6539篇 |
2015年 | 6400篇 |
2014年 | 12029篇 |
2013年 | 14470篇 |
2012年 | 9957篇 |
2011年 | 10324篇 |
2010年 | 8249篇 |
2009年 | 7434篇 |
2008年 | 7143篇 |
2007年 | 7542篇 |
2006年 | 6537篇 |
2005年 | 5689篇 |
2004年 | 4553篇 |
2003年 | 3994篇 |
2002年 | 3252篇 |
2001年 | 2851篇 |
2000年 | 2324篇 |
1999年 | 1834篇 |
1998年 | 1499篇 |
1997年 | 1267篇 |
1996年 | 1069篇 |
1995年 | 941篇 |
1994年 | 744篇 |
1993年 | 566篇 |
1992年 | 509篇 |
1991年 | 465篇 |
1990年 | 392篇 |
1989年 | 337篇 |
1988年 | 336篇 |
1987年 | 281篇 |
1986年 | 221篇 |
1985年 | 258篇 |
1984年 | 226篇 |
1983年 | 168篇 |
1982年 | 166篇 |
1981年 | 163篇 |
1980年 | 130篇 |
1979年 | 123篇 |
1978年 | 65篇 |
1977年 | 42篇 |
1976年 | 49篇 |
1975年 | 32篇 |
排序方式: 共有10000条查询结果,搜索用时 187 毫秒
991.
Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts 总被引:1,自引:0,他引:1
992.
本实验根据中医学对角膜瘢痕的认识以及历代中医应用中药熊胆治疗角膜翳的理论和方法,配制了复方熊胆眼药水.通过复方熊胆眼药水对实验性兔角膜白斑的疗效观察和光镜下兔角膜病理形态学检查,结果提示复方熊胆眼药水有显著的退翳作用,探讨该作用是通过消除角膜的慢性炎症,增加其局部组织代谢来实现的.指出复方熊胆眼药水对临床角膜瘢痕患者的治疗及角膜移植术前的辅助治疗是有积极意义的. 相似文献
993.
冠状动脉造影术,使冠心病的诊断、治疗水平明显提高。但床上排尿困难是术后常见的护理问题,采用常规的方法,效果不佳,常需导尿术解决,既增加了患者的痛苦,又增加了护理工作量。我科2003年3月~2006年10月采取开塞露肛注刺激直肠诱发排便-排尿反射,较好地解决了床上排尿困难的问题。并与常规诱导排尿的方法进行了比较,现报告如下。临床资料对象选择冠状动脉造影术后排尿困难者60例,其中男性42例,女性18例,年龄20~78岁,平均53岁,随机分为对照组和观察组各30例,两组年龄、性别差异无显著性,具有可比性。方法(1)观察组:给予开塞露肛注排便以诱导… 相似文献
994.
Ayala Stabholz Anne A. Nicholas Grenith J. Zimmerman Ulf M. E. Wikesjö 《Journal of clinical periodontology》1998,25(10):794-800
Abstract. 15 adults, each providing 4 non-adjacent untreated periodontal pockets with a probing depth (PD) exceeding 6 mm. volunteered for a randomized, split-mouth, double-blind, clinical study evaluating subgingival irrigation with chlorhexidine (CHX) or tetracycline HCl (TTC). The study protocol included oral hygiene instructions followed by scaling and root planing. Experimental and immediately adjacent teeth did not receive instrumentation. The 4 deep periodontal pockets in each patient were assigned to be irrigated with 150 ml CHX (0.12%). TTC (10 or 50 mg/ml; TTC10, TTC50), or sterile saline (control) in a single episode. Post-irrigation mechanical plaque control was supported by 2× daily CHX rinses throughout the 12-week observation interval. Recordings of oral hygiene (PlI), gingival health (GI). bleeding on probing (BoP). probing depth (PD), clinical attachment level (CAL), and microbial morphotypes from subgingival paper point samples were performed pre-irrigation. and at 1, 2, 4, 6, 8, 10, and 12 weeks post-irrigation. Mean post-irrigation PlI was low, fluctuating between 0.0 and 0.4, without significant differences between experimental groups. Mean pre-irrigation GI approximated 1.4 and reached 0.8 at the exit of study without significant differences between experimental groups. All experimental sites exhibited BoP pre-irrigation. BoP was significantly reduced in TTC50 compared to TTC10, CHX and control sites from week 8 post-irrigation. PDs were reduced for the experimental groups with TTC50 exhibiting the strongest reduction. CALs remained unaltered from pre-irrigation for TTC10. CHX and control sites over the 12-week observation interval, whereas TTC50 sites consistently improved to significantly differ from all other groups at week 10 and 12 post-irrigation. The distribution of bacterial morphotypes was significantly altered towards one of periodontal health for all experimental groups with a profound effect for TTC50 sites. Our results suggest that subgingival irrigation with TTC solutions at high concentrations may have a rôle in the management of adult periodontitis. 相似文献
995.
采用动脉血氧饱和度仪对52例新生儿肺炎患儿,在雾化吸入治疗过程中的动脉血氧饱和度(SaO2)进行了监测,对比了吸氧与否对SaO2改变的影响。结查表明:与基础值比较,雾化吸入时患儿的SaO2显著下降(P<0.01),而雾化吸入同时吸氧者SaO2无明显变化(P>0.05),但两者比较具有显著性差异(P<0.01)。结果提示雾化吸入可使新生儿肺炎患儿SaO2下降;同时吸氧,对防止SaO2的下降有一定作用。 相似文献
996.
原发性肝癌介入治疗中化疗栓塞模式的探索 总被引:1,自引:0,他引:1
为探讨空气作为栓塞剂在原发性肝癌介入中的应用并作出评价,选择13例不能切除的原发性肝癌经肝动脉静灌注化疗后用空气20~30ml栓塞,2~3周一次,反复治疗2~4次,疗程末用碘油阿霉素乳剂作最后栓塞,治疗中观察血象,肝功能,AFP和肿瘤大小的变化,并作长期随访。结果:治疗后肿瘤缩小50%以上者3例,不足50%者9例,变化不明显1例,随访结果6例生存不足6月,3例生存10月,2例12月,另2例生存超过 相似文献
997.
Travis L. Boaz Jonathan S. Lewin Yiu-Cho Chung Jeffrey L. Duerk Mark E. Clampitt John R. Haaga 《Journal of magnetic resonance imaging : JMRI》1998,8(1):64-69
The purpose of this study was to determine the suitability of MRI to accurately detect radiofrequency (RF) thermoablative lesions created under MR guidance. In vivo RF lesions were created in the livers of six New Zealand White rabbits using a 2-mm-diameter titanium alloy RF electrode with a 20-mm exposed tip and a 50-W RF generator. This was performed using a 0.2T clinical C-arm MR imager for guidance and monitoring. Each animal was sacrificed and gross evaluation was performed. Histologic correlation was performed on the first two animals. The MR-compatible RF electrode was easily identified on rapid gradient-echo images used to guide electrode placement. A single lesion was created in each rabbit liver. Lesions ranged from approximately 10 to 17 mm in diameter (mean, 13.5 mm). T2-weighted and short T1 inversion recovery (STIR) images demonstrated lesions ranging in diameter from 12 to 18 mm (mean, 14.6 mm). Lesion dimensions determined from images closely correlated with those determined at gross examination with the discrepancy never exceeding 2 mm, for an r2 value of .87. MRI performed at the time of MR-guided RF ablation accurately demonstrated created lesions. This modality may provide a new option for the treatment of local and regional neoplastic disease. 相似文献
998.
A sixty-year-old man, developed 2–5 mm sized, hyperemic, itchy papules, vesicles, erosions and crusts on hyperemic base on his chest, abdomen, back, gluteal region, and proximal sites of his upper and lower extremities. The direct and indirect immunoflurescence tests were negative. Histology revealed extensive acantholysis in the epidermis in the following forms: pemphigus vulgaris-like suprabasal acantholysis, Darier-like acantholytic dyskeratosis with corps ronds, Hailey-Hailey-like suprabasal clefts, and pemphigus foliaceus-like superficial acantholysis with spongiosis. Using systemic steroids, topical drying, and reepithelising therapy, the patient was cured. He was symptom-free the first, fourth, and thirteenth months after finishing steroid therapy. We review the literature and the new subdivision of the disease according to the histological and clinical features. 相似文献
999.
L. R. G. FAVA 《International endodontic journal》1995,28(2):103-107
A clinical study was carried out on nonvital maxillary central incisors to evaluate the incidence of postoperative pain following single-visit root canal treatment using three different instrumentation techniques. Ninety teeth from 78 patients whose ages ranged from 14 to 63 years were selected and divided into three groups. Each group (30 teeth) was prepared by a different coronal-to-apical technique using different instrument movement depending upon the technique employed: modified double-flared, crown-downpressureless and balanced force techniques. No difference was observed in the incidence of postoperative pain among the groups. 相似文献
1000.
Seiji Kinugasa Shuichi Tachibana Manpei Kawakami Tatsuhiko Orino Ryuichi Yamamoto Shinjiro Sasaki 《Surgery today》1998,28(3):335-338
(Received for publication on Nov. 14, 1996; accepted on May 12, 1997) 相似文献