人参的词源学、生药学、产品及市场的现代评价

随着对人参研究的日益深入，人参产品的价值愈加为人们所认识，更多的含人参的药物被开发、应用于临床。一些国家和地区对人参生产、市场及有关法规做出相应的调整或更新。在参阅大量文献的基础上，对近年来有关人参词源学、生药学（包括植物来源、药材性状、化学性质、种属鉴定）、种植与加工对活性成分的影响、国际市场及相关法规等方面研究进行综述，为进一步开发利用人参及其衍生物提供参考。     

Compound K: A systematic review of its anticancer properties and probable mechanisms

Panax ginseng is a common natural product, which is well-known to have a wide range of pharmacological activities in cancer. Its metabolite, compound K (CK), has been reported to have anticancer activity. We aimed to systematically review the literature for evidence of anticancer effects of CK. We conducted a systematic search in eight databases. We included all in vitro and in vivo studies investigating the anticancer effects of CK with no restrictions. Quality assessment was applied by ToxRTool. Fifty-four articles were included in our study. The purity of CK in our included studies was at least 95%. The in vitro studies reported that CK had a potential anticancer activity on several cell lines including human lung cancer cell lines (A549, PC-9), nasopharyngeal carcinoma cell line (Hk-1), liver cancer cell line (BEL 7402), and pediatric acute myeloid leukemia cell lines (Kasumi-1, MV4-11). The in vivo studies reported a significant decrease in tumor volume in mice treated with CK. CK is a potential supplementary treatment in cancer chemotherapies. The safety and further clinical trials of CK should be explored for future drug development.