Coronary Sinus Obstruction after Atrioventricular Canal Defect Repair

The coronary sinus can become obstructed with any instrumentation at or near the ostium such as in atrioventricular canal defect repairs. This complication may lead to a wide range of consequences including dyspnea, angina, myocardial infarction, and sudden death. The following report illustrates the importance of careful perioperative echocardiographic evaluation of the coronary sinus in procedures that may affect the sinus and its ostium.     

眼眶瘘管的特点及治疗分析

目的 探讨不同病因眼眶瘘管的特点及治疗方法.方法 回顾性分析1980年1月至2007年7月就诊的眼眶瘘管患者37例.结果 37例中异物引发的21例.眼眶囊肿引发的9例.眼眶感染性炎症引发的6例.嗜酸性肉芽肿1例,如瘘管可排出脓液、豆渣样物及澄清液体,分别提示感染性炎症、皮样囊肿及非感染性因素.结论 眼眶瘘管形成的常见原因是异物存留、皮样囊肿(包括表皮样囊肿)和骨髓炎.     

Sinus histiocytosis with massive lymphoadenopathy (Rosai-Dorfman disease). Clinico-pathological analysis of a paediatric case

Histochemical and immunohistochemical studies performed in only a few cases of sinus histiocytosis with massive lymphoadenopathy (SHML) indicated that SHML cells belong to themacrophage — histiocyte system, though their exact origin is still uncertain. We analyzed the morphological, antigenic and enzymatic characteristics of the histiocyte-like cells in one paediatric case of SHML (also named Rosai-Dorfman disease). The SHML cells expressed the S-100 protein, lectins concanavalin A, peanut agglutinin andmonocyte-macrophage related antigens CD 11c, CD 14, CD 33, CD 68 and LN 5. Reactivity with other anti-macrophage antibodies (MAC 387, lysozyme, alpha-1 anti-chymotrypsin) was variable. The CD1a antigen was present only in scattered cells, whereas HLA-DR and the HLA-DR associated invariant chain were absent. Cytochemistry demonstrated an intense activity of acid phosphatase and non specific esterase of SHML cells. A large amount of medium sized mononuclear cells were located in the sinuses and intersinusoidal tissue. Our findings suggest that SHML cells have intermediate features between phagocytes and Langerhans cells/interdigitating reticulum cells. The heterogeneity of marker expression on SHML cells might be related to the local content of factors (e.g., cytokines), capable of modulating the phenotype of monocyted and derived cells.     

Sinus tachycardia in term infants preceding sudden infant death

The quantities of sinus tachycardia in 24-h recordings of the electrocardiogram from 16 full-term infants (37 weeks gestation) who were subsequently victims of the sudden infant death syndrome (SIDS), from 230 randomly selected age-matched full-term survivors and from 64 full-term survivors matched for age and birth weight were measured by computer and manual analysis techniques. Of 16 infants dying of SIDS, 7 had elevated levels of sinus tachycardia (>95th centile in controls) (P<0.01). Although high levels of sinus tachycardia might be of value in identifying infants at high risk of SIDS, these encouraging findings must first be validated by further prospective studies.Abbreviations IHR instantaneous heart rate - SIDS sudden infant death syndrome - ECG electrocardiogram     

功能性内窥镜鼻窦手术在老年患者的应用

目的 探讨功能性内窥镜鼻窦手术在老年慢性鼻窦炎、鼻息肉患者的应用及其疗效。方法 总结74例≥岁老年慢性鼻窦炎、鼻息肉患者行功能性内窥镜手术的临床资料,以同期行相同手术的199例59岁以下患者为对照组。结果 老年组与对照组手术治愈率分别为79．5％和77．9％。结论 功能性内窥镜鼻窦手术同样适合于老年患者,可望提高老年患者的生存质量。     

鼻内窥镜手术切除鼻腔鼻窦内翻性乳头状瘤

［摘要］目的：探讨内窥镜下切除鼻腔鼻窦内翻性乳头状瘤的效果。方法：对15例鼻腔鼻窦内翻性乳头状瘤患者施行鼻内窥镜手术。结果：随访2～4年，仅1例复发，余者均未见复发。结论：鼻内窥镜有多视角、清晰度高、损伤小、不毁容等优点，是治疗鼻腔鼻窦内翻性乳头状瘤的一种很好的方法。     

Long-term effects of postoperative measures after sinus surgery

To compare the long-term effects of different postoperative treatment regimes after functional endoscopic sinus surgery (FESS), we performed a randomized controlled trial. Inclusion criteria were chronic rhinosinusitis with (CRSwNP) or without (CRS-NP) bilateral nasal polyps and acute recurrent rhinosinusitis (ARR). All patients (male/female = 56/65; mean age = 42.8 years; age range 18–73 years) underwent sinus surgery for the first time. The patients included in 2004 were allocated to a packing in middle meatus for 5 days or saline irrigation only postoperatively. The patients included in 2005 were randomized to debridement 6 and 12 days postoperatively or saline irrigation. At baseline and 56 weeks (32–77) postoperatively, the patients reported symptoms such as nasal congestion, facial pain, headache, and change in sense of smell, nasal discharge, sneezing and reduced general condition on visual analogue scale (VAS). We used ANCOVA to compare symptom improvement. Among patients with CRSwNP, nasal congestion and sneezing improved, respectively, 20 mm (P value = 0.041) and 18 mm (P value = 0.011) more in the debridement group than in the saline irrigation group. Although a packing had positive effects on the symptom improvement they were not significant. Patients with CRSwNP, who had undergone debridement after FESS, had significantly larger symptom improvement 56 weeks after surgery than patients who had only done saline irrigation.     

鼻内镜脑垂体瘤手术

目的探讨鼻内镜脑垂体瘤手术的方法与疗效。方法鼻内镜单鼻孔蝶窦口入路手术治疗11例脑垂体瘤患者,其中生长激素瘤2例,泌乳素瘤2例,无功能腺瘤7例。11例患者均有不同程度头痛,泌乳异常2例,肢端肥大症2例,不同程度视力异常6例。结果11例患者均一次性切除脑垂体瘤,随访2年无复发,所有患者头痛症状消失,视力异常与泌乳异常恢复,肢端肥大症状无变化。术后1例患者出现短暂多尿现象,1例患者出现短暂脑脊液漏,经保守治疗均治愈。结论鼻内镜脑垂体瘤手术优点为微创、无面部切口、视野清晰、操作简单、安全有效且恢复快;不足之处在于单手操作,内镜容易被血液污染,出血较多时手术操作有一定困难。