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61.
醒脑静注射液对脑出血病人高热昏迷的疗效观察   总被引:2,自引:0,他引:2  
目的:观察醒脑静注射液对脑出血病人高热与意识障碍的疗效。方法:按随机分组法将100例有高热与意识障碍的脑出血病人随机分为治疗组及对照组,治疗组在常规方法上加用醒脑静注射液,对照组采用常规方法。结果:治疗组恢复时间明显短于对照组。结论:醒脑静注射液对脑出血高热及意识障碍有明显治疗效果。  相似文献   
62.
Objective: To evaluate the efficacy and safety of Qingkailing Injection(清开灵注射液, QKL) for treatment of children pneumonia caused by respiratory syncytial virus(RSV). Methods: Randomized clinical trials(RCTs) comparing QKL with ribavirin injection in the treatment of children pneumonia induced by RSV were searched in Pub Med, Science Direct, Cochrane Library, Chinese VIP database, CNKI and Wanfang databases from their inception to March 2014. Meta-analyses were performed using RevMan 5.2 software. The methodological quality of the selected RCTs was evaluated by the Modified Jadad Score. The primary outcome measures were effective rate and the secondary outcomes were relief time of fever and cough. Results: Seven RCTs with 992 cases published from 2008 to 2013 were identified. The meta-analysis results indicated that QKL was more effective in cure rate [risk ratios(RR)=1.32, 95% CI(1.17, 1.50), P0.01], total effective rate [RR=1.07, 95% CI(1.02, 1.13), P=0.009] and less fever clearance time [mean difference=–0.73, 95% CI(–1.22, –0.23), P=0.004], compared with ribavirin injection in the treatment of RSV-induced children pneumonia. No dead case was reported in all trials. There were 3 trials mentioned adverse events, 2 reported no obvious adverse event occurred while 1 reported adverse events described as skin hypersensitivity, elevation of ALT, a mild abnormal of hepatic and renal function in both QKL and ribavirin group. Conclusions: QKL was an effective and relatively safe option for the treatment of RSV-induced children pneumonia. These therapeutic effects were promising but need to be interpreted with caution due to variations in the treatment and methodological weakness in the studies.  相似文献   
63.
目的分析注射用阿莫西林钠克拉维酸钾配伍液变色和沉淀的原因,提出预防措施,确保临床用药安全有效。方法查阅相关文献,从中获取阿莫西林钠和克拉维酸钾的稳定性资料,解释变色沉淀现象。结果本品配伍液变色与阿莫西林钠和克拉维酸钾在一定条件下(水分、温度、光线、溶媒及pH值、时间)分解有关;沉淀与配伍时温度低、pH值低、浓度高有关。结论本品应密闭,在凉暗干燥处(≤20℃)保存,用0.9%氯化钠注射液(pH值6.5~7.0)溶解,立即稀释至1.2g/100ml,并在2h内(20℃以下暗处)完成整个输液过程。  相似文献   
64.
含吐温80中药注射剂对不同动物的过敏反应   总被引:3,自引:0,他引:3  
目的:观察吐温80及含吐温80的中药注射剂对不同动物的过敏反应,阐明不同动物出现毒性反应的原因.方法:在犬和猴两种不同种属的动物体内,分别静注或静滴0.35%吐温80溶液及含相同百分含量吐温80的中药注射剂,观察动物的血压、心率、心电图及过敏反应.结果:犬静滴吐温80溶液及含吐温80的中药注射剂5ml·kg-1(内含吐温80 17.5mg·kg-1)后,均出现血压下降、心率减慢及皮肤红斑、流涎呕吐、痉挛抽搐等过敏反应;而猴静注或静滴吐温80溶液及含有吐温80的中药注射剂10ml·kg-1(内含吐温80 35mg·kg-1),未出现过敏反应.结论:犬对吐温的过敏反应是动物的种属性特异反应.  相似文献   
65.
目的:评价复方苦参注射液在胃肠肿瘤化疗周期初升白细胞作用及疗效。方法:选取167名化疗周期前伴有白细胞下降的胃肠肿瘤患者,分为复方苦参治疗组92例,给予复方苦参注射液治疗,对照组75例给予常规升白细胞治疗,二组进行对照。结果:治疗组升白细胞有效率87.0%,优于对照组,有统计学差异(P〈0.05)。结论:对胃肠肿瘤化疗前伴有白细胞下降患者,应用复方苦参注射液可获得较快的提升白细胞能力,同时减轻化疗的毒副作用,提高患者耐受力。  相似文献   
66.
Objective: To study the effect of Shenqi Fuzheng Injection (参芪扶正注射液,SFI) on cellular immune in patients with mammary cancer (MC) after chemotherapy. Methods: One hundred and ten patients with MC were randomly assigned to two groups. The 58 patients in the tested group were treated with SFI in cooperation with chemotherapy of CAF protocol (Cyclophosphamide, Doxorubicin and Fluorouracil), while the 52 patients in the control group were treated with chemotherapy of the same protocol alone. Changes of the patients' quality of life (QOF), adverse reaction that occurred, peripheral lymphocyte count and killing activity of single karyocyte before and after treatment between the two groups were compared. Results: Patients' QOF elevating rate after treatment in the tested group and the control group was 34.5% and 13.5% respectively; The lowering of peripheral blood cell count of WBC, platelet and lymphocyte as well as that of the killing activity of single peripheral karyocyte on various kinds of MC cells were all milder and recovery sooner than those in the control group. Conclusion: SFI in combination with chemotherapy in treating MC could reduce the occurrence of adverse reaction to chemotherapy, improve clinical symptoms, elevate QOF and enhance immunity in patients with MC.  相似文献   
67.
当归、黄芪注射液对鸡胚绒毛尿囊膜血管生成的影响   总被引:2,自引:0,他引:2  
目的探讨当归、黄芪注射液对鸡胚绒毛尿囊膜(chorioallantoic membrane,CAM)血管生成的影响。方法种蛋在37.8℃孵育7d后制备CAM模型,当归、黄芪注射液及其不同配比滴加于CAM表面的载体上,继续孵育3d,观察鸡胚存活状况,然后制备鸡胚CAM标本,解剖显微镜下计数新生毛细血管数目。结果当归、黄芪注射液及其不同配比均具有促进鸡胚CAM血管生成作用,与生理盐水对照组相比有显著性差异(P<0.05),除当归与黄芪1∶5,其他各组药效低于表皮生长因子(EGF)(P<0.05)。结论当归注射液、黄芪注射液及其不同配比具有显著促进鸡胚CAM血管生成作用,其可能的机制是血管内皮细胞的增殖与迁移。  相似文献   
68.
目的探讨大鼠肠粘连动物模型的制备方法。方法SD大鼠随机分为实验组和对照组,实验1组腹腔注射1%甲醛,实验2组注射0.5%甲醛,实验3组注射0.5%盐酸,实验4组采用Galili法制备大鼠肠粘连动物模型,x^2检验对结果进行统计学分析。结果大鼠在腹腔注射1%甲醛与0.5%盐酸后均100%发生肠粘连,注射0.5%甲醛的大鼠肠粘连的发生率为87.5%,且0.5%盐酸,1%甲醛,0.5%甲醛腹腔注射法与Galili法相比,差异无显著性。结论采用1%甲醛,0.5%盐酸腹腔注射法分别建立了简便易行的大鼠肠粘连动物模型.  相似文献   
69.
目的:观察丹参注射液对小鼠Lewis肺癌细胞周期素D1(Cyelin D1)的表达.方法:建立Lewis肺癌小鼠模型,用免疫组织化学方法检测丹参对肿瘤细胞Cyclin D1表达的影响,测肿瘤体积、瘤重.结果:生理盐水组Cyclin D1阳性表达率与丹参组和环磷酰胺组有显著性差异,而后两组差异无显著性.结论:丹参可抑制小鼠Lewis肺癌Cyclin D1的异常表达并抑制小鼠IJewis肺癌生长.  相似文献   
70.
Objective: To confirm the effect of Shengmai Injection (生脉注射液, SMI) in improving cardiac function in patients with acute coronary syndrome (ACS) and to explore its influence on inflammatory reaction in patients. Methods: Ninety ACS patients were randomized into two groups, the control group treated with conventional therapy and the SMI group treated with SMI. The patients' cardiac function was noted and the content of high sensitive C-reactive protein (hs-CRP) in venous blood was measured before treatment and 1 week and 3 weeks after treatment, so as to observe and compare their changes between the two groups. Results: The cardiac output, stroke volume and ejection fraction in the SMI group after 3 weeks of treatment were all higher than those in the control group (P〈0.05). The serum content of hs-CRP was reduced in both groups (P〈0.05), but the reduction in the SMI group was more significant than that in the control group (P〈0.05). Conclusion: SMI could improve the cardiac function and further inhibit the inflammatory reaction in patients with ACS.  相似文献   
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