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101.
目的：对安痛定注射液中的三组分实行分光光度法同时测定。方法：对传统的多波长线性回归分光光度法进行改进,使其不需要等吸收波长。结果：９份模拟样品中氨基比林、安替比林、巴比妥的平均回收率分别为９９．９％、９９．８％、１００．３％,相对标准偏差分别为０．５％、１．０％、１．７％。对３个批号实际样品的测定结果与标准方法一致。结论：方法简便快捷,适于安痛定注射液的制剂分析。 相似文献
102.
Attention is directed to the potential danger of therapy with haloperidol in children. Its value in reducing the excessive movements of Sydenham chorea must be weighed against the usual tendency of this disorder to remit spontaneously and the occasional tendency of the drug to cause castastropic adverse reaction 相似文献
103.
目的观察促进剖宫产术后肛门排气有效的方法。方法回顾性分析我院自2007年6月～2009年6月对84例剖宫产术后的产妇随机分三组,分别给予中药排气汤、乳果糖口服溶液、开塞露三种方法促其排气,观察比较三组产后机体恢复情况和对宫高的影响。结果三组药物治疗后腹胀均有明显缓解,术后早期排气、排尿和排便效果上,开塞露组〉乳果糖组〉中药排气汤组,经统计学检验有显著性差异（P〈0.05）。中药排气汤组对促子宫收缩的影响与乳果糖组或开塞露组经统计学检验有差异（P〈0.05）。结论中药排气汤、开塞露或乳果糖,均可减轻术后腹胀,有利于产妇身体的康复,更有利于母乳喂养。 相似文献
104.
105.
卢晓峰 《河南中医学院学报》2009,24(5)
卢海涛老师治学严谨,锲而不舍,博极医源,注重实践,辨证精确,善治内妇科疑难杂症。耳轮灼痛案,实因阴虚火旺,风热上乘,治以滋阴降火,平肝熄风;戒烟后口腔溃疡案,实因脾胃虚弱、湿热内蕴、阴虚血燥,治以益气健脾、清化湿热、养阴凉血;尿频案,实因脾肾阳虚,固摄失权,治以湿补脾肾,缩泉固关。 相似文献
106.
Susceptibility testing of anaerobic bacteria 总被引：4，自引：0，他引：4
With the significant increase in resistance of anaerobic bacteria to antimicrobial agents in recent years, susceptibility testing of these organisms becomes very important. In addition to survey studies, hospitals should be determining their local patterns, and therapy of at least the more serious infections should be guided by susceptibility tests. Of the various tests available, those most suitable for smaller hospitals for guidance of patient management are the broth disc elution procedure and the micro broth dilution tray test. 相似文献
107.
Heung Bae Kim Khashayar Vakili Gabriel J. Ramos-Gonzalez Deborah R. Stein Michael A. Ferguson Diego Porras James E. Lock Gulraiz Chaudry Ahmad Alomari Steven J. Fishman 《Journal of vascular surgery》2018,67(6):1664-1672
Background
Midaortic syndrome (MAS) is a rare condition characterized by stenosis of the abdominal aorta. Patients with disease refractory to medical management will usually require either endovascular therapy or surgery with use of prosthetic graft material for bypass or patch angioplasty. We report our early experience with a novel approach using a tissue expander (TE) to lengthen the normal native arteries in children with MAS, allowing primary aortic repair without the need for prosthetic graft material.Methods
We conducted a retrospective review of patients with MAS undergoing the TE-stimulated lengthening of arteries (TESLA) procedure at our institution from 2010 to 2014. Data are presented as mean (range).Results
Five patients aged 4.8 years (3-8 years) underwent the TESLA procedure. Stages of this procedure include the following: stage I, insertion of retroaortic TE; stage II, serial TE injections; and stage III, final repair with excision of aortic stenosis and primary end-to-end aortic anastomosis. Stage II was completed in 4 months (1-9 months) with 12 (7-20) TE injections. Goal lengthening was achieved in all patients. Stage III could not be completed in one patient because of extreme aortic inflammation, which precluded safe excision of the aortic stenosis and required use of a prosthetic bypass graft. The other four patients completed stage III with two (one to three) additional vessels also requiring reconstruction (renal or mesenteric arteries). At 3.2 years (1-6 years) of follow-up, all patients are doing well.Conclusions
The TESLA procedure allows surgical correction of MAS without the need for prosthetic grafts in young children who are still growing. 相似文献108.
Shinsuke Kikuchi Lihua Chen Kevin Xiong Yukihiro Saito Nobuyoshi Azuma Gale Tang Michael Sobel Thomas N. Wight Richard D. Kenagy 《Journal of vascular surgery》2018,67(5):1556-1570.e9
Objective
Venous valves are essential but are prone to injury, thrombosis, and fibrosis. We compared the behavior and gene expression of smooth muscle cells (SMCs) in the valve sinus vs nonvalve sites to elucidate biologic differences associated with vein valves.Methods
Tissue explants of fresh human saphenous veins were prepared, and the migration of SMCs from explants of valve sinus vs nonvalve sinus areas was measured. Proliferation and death of SMCs were determined by staining for Ki67 and terminal deoxynucleotidyl transferase dUTP nick end labeling. Proliferation and migration of passaged valve vs nonvalve SMCs were determined by cell counts and using microchemotaxis chambers. Global gene expression in valve vs nonvalve intima-media was determined by RNA sequencing.Results
Valve SMCs demonstrated greater proliferation in tissue explants compared with nonvalve SMCs (19.3% ± 5.4% vs 6.8% ± 2.0% Ki67-positive nuclei at 4 days, respectively; mean ± standard error of the mean, five veins; P < .05). This was also true for migration (18.2 ± 2.7 vs 7.5 ± 3.0 migrated SMCs/explant at 6 days, respectively; 24 veins, 15 explants/vein; P < .0001). Cell death was not different (39.6% ± 16.1% vs 41.5% ± 16.0% terminal deoxynucleotidyl transferase dUTP nick end labeling-positive cells, respectively, at 4 days, five veins). Cultured valve SMCs also proliferated faster than nonvalve SMCs in response to platelet-derived growth factor subunit BB (2.9 ± 0.2-fold vs 2.1 ± 0.2-fold of control, respectively; P < .001; n = 5 pairs of cells). This was also true for migration (6.5 ± 1.2-fold vs 4.4 ± 0.8-fold of control, respectively; P < .001; n = 7 pairs of cells). Blockade of fibroblast growth factor 2 (FGF2) inhibited the increased responses of valve SMCs but had no effect on nonvalve SMCs. Exogenous FGF2 increased migration of valve but not of nonvalve SMCs. Unlike in the isolated, cultured cells, blockade of FGF2 in the tissue explants did not block migration of valve or nonvalve SMCs from the explants. Thirty-seven genes were differentially expressed by valve compared with nonvalve intimal-medial tissue (11 veins). Peptide-mediated inhibition of SEMA3A, one of the differentially expressed genes, increased the number of migrated SMCs of valve but not of nonvalve explants.Conclusions
Valve compared with nonvalve SMCs have greater rates of migration and proliferation, which may in part explain the propensity for pathologic lesion formation in valves. Whereas FGF2 mediates these effects in cultured SMCs, the mediators of these stimulatory effects in the valve wall tissue remain unclear but may be among the differentially expressed genes discovered in this study. One of these genes, SEMA3A, mediates a valve-specific inhibitory effect on the injury response of valve SMCs. 相似文献109.
Simon Hsu Dena E. Rifkin Michael H. Criqui Natalie C. Suder Pranav Garimella Charles Ginsberg Antoinette M. Marasco Belinda J. McQuaide Emma J. Barinas-Mitchell Matthew A. Allison Christina L. Wassel Joachim H. Ix 《Journal of vascular surgery》2018,67(6):1855-1863.e1
Background
Chronic kidney disease (CKD) is strongly associated with peripheral artery disease (PAD). Detection of subclinical PAD may allow early interventions for or prevention of PAD in persons with CKD. Whether the presence of atherosclerotic plaque and femoral intima-media thickness (IMT) are associated with kidney function is unknown.Methods
We performed a cross-sectional observational study of 1029 community-living adults. We measured superficial and common femoral artery IMT and atherosclerotic plaque presence by ultrasound. Estimated glomerular filtration rate (eGFR; continuous) and eGFR <60 mL/min/1.73 m2 (binary) were evaluated as outcomes.Results
Mean age was 70 ± 10 years, mean eGFR was 78 ± 17 mL/min/1.73 m2, and 156 (15%) individuals had eGFR <60 mL/min/1.73 m2; 260 (25%) had femoral artery plaque. In models adjusted for demographics and cardiovascular risk factors, individuals with femoral artery plaque had mean eGFR approximately 3.0 (95% confidence interval, ?5.3 to ?0.8) mL/min/1.73 m2 lower than those without plaque (P < .01). The presence of plaque was also associated with a 1.7-fold higher odds of eGFR <60 mL/min/1.73 m2 (95% confidence interval, 1.1-2.8; P < .02). Associations were similar in persons with normal ankle-brachial index. The directions of associations were similar for femoral IMT measures with eGFR and CKD but were rendered no longer statistically significant with adjustment for demographic variables and cardiovascular disease risk factors.Conclusions
Femoral artery plaque is significantly associated with CKD prevalence in community-living individuals, even among those with normal ankle-brachial index. Femoral artery ultrasound may allow evaluation of relationships and risk factors linking PAD and kidney disease earlier in its course. 相似文献110.
Grace J. Wang Benjamin M. Jackson Paul J. Foley Scott M. Damrauer Philip P. Goodney Rachel R. Kelz Christopher Wirtalla Ronald M. Fairman 《Journal of vascular surgery》2018,67(6):1649-1658