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991.
Manar Hussein Abdel-Sattar Omar Abdelaziz Amr Othman Othman Sherief Mohamed El-Refaei 《The Egyptian Journal of Radiology and Nuclear Medicine》2018,49(1):209-215
Objective
Our aim was evaluate the role the PET/CT in the assessment of response to therapy in patients with Non-Hodgkin extra-nodal lymphoma: in particular, a five-point scale (Deauville criteria), which can be employed for early- and late-therapeutic response assessment.Methods
Sixty patients with pathologically confirmed Non-Hodgkin lymphoma (NHL) were enrolled in this prospective study. All patients underwent the following PET/CT examinations: initial PET/CT for staging, interim PET/CT and end of treatment PET/CT. Response assessment was done using new Cheson’s guidelines and five-point scale (Deauville criteria).Results
All patients were evaluated for response to therapy in the early interim, followed by late interim, as well as end treatment assessment for the overall response. We found good concordance of response assessment according to the Deauville criteria classification with International Harmonization Project (IHP) classification. After early interim 48/60 patients had concordant designations (91.7%, 83.3%, 70%, and 33.3%) and 12 patients had discordant designations. After late interim, 56/60 patients had concordant designations (100%, 100%, 80%, and 50%) and four patients had discordant designations. After end of treatment, 54/60 patients had concordant designations (100%, 100% and 71.4%) and six patients has discordant designations.Conclusion
Response assessment according to the Deauville criteria classification showed good concordance with IHP classification. According to our findings, we recommend the use of Deauville criteria in reporting of PET/CT for staging and assessment of response to treatment. 相似文献992.
993.
N K Cheung J Blessing-Moore M J Reid N J Lewiston G Yang 《The Journal of allergy and clinical immunology》1983,71(3):283-293
By means of monoclonal mouse anti-human IgE antibody, the microtiter solid-phase radioimmunoassay (MSPRIA) was modified to measure honeybee venom (HBV) IgE. HBV IgG was measured by MSPRIA(G) using affinity column purified goat anti-human IgG antibody and correlated with results obtained with staphylococcal protein A-SPRIA. Nonlinear specific IgE dilution curves were associated with high HBV IgG content. By serial transfer and assay of the supernatant, the interference of IgE by specific IgG could be reduced. The degree of interference was correlated with the specific IgG content. The principle of serial supernatant transfer and assay was applied to the standardization of reference HBV IgE serum, and the quantitation of HBV IgE contents in patients and controls. HBV IgE levels in patients allergic to honeybee stings correlated with the skin-test endpoint titrations. While 75% of the allergic patients were skin-test positive, 83% of them were IgE positive by the MSPRIA and 67% were IgE positive by the RAST. 相似文献
994.
Erin M. Lowery William Adams Shellee A. Grim Nina M. Clark Leah Edwards Jennifer E. Layden 《Journal of cystic fibrosis》2017,16(6):727-734
Background
Post-transplant lymphoproliferative disease (PTLD) is an important cause of morbidity and mortality following lung transplantation. Recipients with cystic fibrosis (CF) may have an increased risk of PTLD although the literature is limited to single center cohorts. Our primary aim is to examine PTLD in an adult lung transplant population by utilizing the International Society for Heart and Lung Transplantation Registry.Methods
We studied 30,598 adult recipients of lung transplants performed between 1999 and 2011. The primary outcome was development of and time to PTLD. In addition to indication for transplant, other predictors examined included Epstein–Barr virus (EBV) and cytomegalovirus (CMV) serostatus, gender, and age. Outcomes were assessed with univariable and multivariable Cox proportional hazard models to obtain hazard ratios (HR).Results
17% of the cohort had a diagnosis of CF. PTLD developed in 2% of CF recipients compared to 1% for non-CF recipients (p < 0.001). Compared to non-CF recipients, CF recipients had higher prevalence of EBV and CMV seronegativity and higher prevalences of high risk EBV and CMV mismatch (D +/R ?). There is a significant association between CF and the development of PTLD [HR 1.66 (95% CI 1.30–2.12)]. Stratified multivariable analysis controlling for age revealed EBV negative non-CF recipients have an almost 2 fold increased risk of developing PTLD, whereas EBV negative CF recipients had an almost 6.5 fold increased risk.Conclusions
CF recipients have a higher risk for PTLD compared to non-CF recipients. Further studies are needed to account for additional risk factors and management in this population post-transplant. 相似文献995.
996.
Nonparameningeal head and neck rhabdomyosarcoma in children and adolescents: Lessons from the consecutive International Society of Pediatric Oncology Malignant Mesenchymal Tumor studies 下载免费PDF全文
Daniel Orbach MD Veronique Mosseri MD Soledad Gallego MD Anna Kelsey MD Christine Devalck MD Bernadette Brenann MD Max M. van Noesel MD PhD Christophe Bergeron MD Johannes H. M. Merks MD PhD Catherine Rechnitzer MD Meriel Jenney MD Veronique Minard–Colin MD PhD Michael Stevens MD PhD 《Head & neck》2017,39(1):24-31
997.
Improving Care Transitions Management: Examining the Role of Accountable Care Organization Participation and Expanded Electronic Health Record Functionality 下载免费PDF全文
998.
本文就G20杭州峰会医疗保障医疗点的设置原则和场馆医疗点、定点酒店医疗点的布置作了阐述;并就医疗保障医疗点的人员配置、设备配备、处置流程、保障任务等作了介绍,为国际大型会议活动医疗保障医疗点的设置提供借鉴。 相似文献
999.
1000.
Seungho Lee Miyeon Shin Yun-Chul Hong Jin Hee Kim 《International journal of hygiene and environmental health》2017,220(2):407-414