半夏厚朴汤处方的药材特性和显微鉴定

目的对中药半夏厚朴汤所用生药材进行药材品种特性与显微鉴定研究。方法首先对半夏厚朴汤所用的生药材进行品种性状鉴定,然后常规粉碎,过65目筛,在显微镜下观察组织特征。结果半夏厚朴汤所用药材均为药典规定品种。结论本项研究对半夏厚朴汤的质量鉴别和临床应用等提供了可靠依据。     

炙甘草合剂中甘草酸含量测定

目的：控制炙甘草合剂的质量。方法：采用高效液相色谱法（HPLC）测定甘草酸的含量。结果：分离度好，含量测定线性范围0．23-1．85μg（r=0．9999），平均回收率96．6％，相对标准差（RSD）0．17％（n=6）。结论：方法简便、准确、重现性好。     

A model for learning to segment temporal sequences, utilizing a mixture of RNN experts together with adaptive variance

This paper proposes a novel learning method for a mixture of recurrent neural network (RNN) experts model, which can acquire the ability to generate desired sequences by dynamically switching between experts. Our method is based on maximum likelihood estimation, using a gradient descent algorithm. This approach is similar to that used in conventional methods; however, we modify the likelihood function by adding a mechanism to alter the variance for each expert. The proposed method is demonstrated to successfully learn Markov chain switching among a set of 9 Lissajous curves, for which the conventional method fails. The learning performance, analyzed in terms of the generalization capability, of the proposed method is also shown to be superior to that of the conventional method. With the addition of a gating network, the proposed method is successfully applied to the learning of sensory–motor flows for a small humanoid robot as a realistic problem of time series prediction and generation.     

Socioeconomic inequalities in health dynamics: A comparison of Britain and the United States

Drawing on theory and research on the fundamental causes of health, the life course, and the welfare state, we investigate social inequalities in dynamic self-rated health for working-aged Britons and Americans. We use data from the British Household Panel Survey and Panel Study of Income Dynamics (1990–2004) and a mixture latent Markov model to test a theoretical model of health as a discrete state that may remain stable or change over time. Our contributions are threefold. First, our finding of three distinctive types of health processes (stable good health, stable poor health, and a “mover” health trajectory) represents a more differentiated profile of long-term health than previously shown. Second, we characterize health trajectories in structural terms by suggesting who was more likely to experience what type of health trajectory. Third, our more differentiated picture of dynamic health leads to a more nuanced understanding of comparative health: Although the health advantage of Britons was confirmed, our results also indicate that they were more likely to experience health change. Moreover, the socioeconomic gradient in long-term health was steeper in the US, raising provocative questions about how state policies and practices may affect population health.     

凉血散瘀合剂微生物限度检查方法的研究

目的建立凉血散瘀合剂的微生物限度检查方法。方法采用接种阳性对照菌回收率试验测定其是否含抑菌成分。结果凉血散瘀合剂五种阳性试验菌的回收率试验结果均高于70%,表明在该实验条件下无抑菌现象。结论凉血散瘀合剂可按常规方法进行微生物限度检查。     

半夏厚朴汤加味对慢性强迫游泳模型小鼠免疫功能的影响

[目的]采用动物实验的方法研究半夏厚朴汤加味对慢性强迫游泳模型小鼠治疗中对免疫功能的调节作用。[方法]实验分为空白组、模型组、中药组、西药组,连续7天强迫游泳造模后测定血清中抗体(溶血素)含量及脾淋巴细胞增殖率。[结果]与模型组相比,其它3组小鼠血清中抗体(溶血素)的含量及脾淋巴细胞增殖率均大于模型组,并有明显的差异(P<0.05)。[结论]半夏厚朴汤加味能够促进模型小鼠血清中抗体的产生及脾淋巴细胞的增殖。     

胰胆合剂灌肠治疗急性水肿性胰腺炎疗效观察

目的：观察胰胆合剂对急性水肿性胰腺炎的临床治疗作用。方法：将８１例急性水肿性胰腺炎患者随机分成治疗组４１例和对照组４０例，治疗组采用中药胰胆合剂灌肠治疗，对照组采用西医综合治疗。结果：（１）治疗组与对照组显效率分别为８７．８％和７０．０％，２组比较有显著性差异（Ｐ＜０．０５）。（２）治疗组在疼痛缓解时间〔（９．５３±３．４８）小时〕、疼痛消失时间〔（１６．８０±１０．４４）小时〕、发热消退时间〔（２．１８±１．１３）日〕及尿淀粉酶恢复正常时间〔（２．３３±１．２５）日〕等方面均明显优于对照组〔分别为（１５．９０±６．１２）小时、（３４．０６±１３．１８）小时、（３．４２±１．４２）日和（４．２６±１．６０）日，Ｐ均＜０．００１〕。结论：中药胰胆合剂灌肠治疗急性水肿性胰腺炎在尽快解除患者痛苦、缩短疗程、促进康复等方面有着一定的价值。     

排气汤对剖宫产术后胃肠功能恢复的影响

目的分析排气汤促进剖宫产术后胃肠功能恢复的作用。方法采用随机数字表法将2018年1月—2019年1月收治的120例剖宫产术产妇分为对照组(60例)、观察组(60例)。对照组产妇采用优质护理模式,观察组在对照组基础上结合中医排气汤治疗,对比2组产妇术后肠胃功能恢复效果以及术后12 h的腹胀、恶心呕吐、发热的症状积分。结果术后72 h,观察组产妇腹胀、恶心呕吐、发热等症状积分均低于对照组,差异有统计学意义(P<0.05);观察组产妇术后首次排气时间、肠鸣音恢复时间、首次排便时间较对照组短,差异有统计学意义(P<0.05)。结论对剖宫产产妇术后施以排气汤可有效降低其肠胃功能症状,促进肠胃功能恢复。     

痹康饮合剂对胶原性关节炎大鼠IL-1β和TNF—α的影响

目的 观察痹康饮合剂对胶原性关节炎的治疗作用，探讨痹康饮合剂（Bikangyin Mixture，BKY）治疗类风湿性关节炎（RA）的可能免疫作用机制。方法 牛源性CII皮下注射诱导建立胶原性关节炎模型随机分为正常组、痹康饮高剂量组、痹康饮低剂量组、甲氨喋呤（Methotrexat，MTX）组、模型对照组。观察比较各组大鼠细胞因子IL-1β和TNF—α水平的变化。结果 痹康饮合剂能显著降低CIA大鼠血清异常增高的IL-1β、TNF—α水平，其治疗作用与甲氨喋呤大致相同，但不良反应较甲氨喋呤小。结论 痹康饮合剂治疗CIA大鼠的作用机制可能与下调致炎细胞因子IL-1β和TNF—α有关。     

复方铋合剂的制备及质量控制

目的 制备复方铋合剂(MBC)并建立其质量控制方法 .方法 以枸橼酸铋铵为主药与氯化钾、甘油、陈皮酊等配成复方铋合剂,采用络合滴定法检测本品中铋的含量,并对制剂的稳定性进行了观察.结果 复方铋合剂的制备工艺简单,质量稳定,含量测定快速、准确.结论 该制剂工艺可用于常规制备复方铋合剂.