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991.
J. de Pedro-Cuesta L. Widén-Holmqvist P. Bach-y-Rita 《Acta neurologica Scandinavica》1992,86(5):433-439
In all, 22 reports of 20 randomized, controlled rehabilitation studies were evaluated. In 18 of these, the design of the trial was parallel, with a cross-over format being employed in the remaining 2 instances. Seven studies related to intensive rehabilitation during the early post-acute period. In six others, specific techniques--sometimes associated with traditional physiotherapy procedures--were compared: biofeedback, perceptual retraining, and amphetamine treatment. Eight experiments evaluated speech therapy in aphasia. Frequently, methodological considerations limited the interpretation of the results. The review showed that: 1) as regards activities of daily life and motor function, differences as between rehabilitation in stroke units on the one hand and non-rehabilitation or rehabilitation in medical wards on the other, were detected in relatively few quality studies and remained particularly inconclusive insofar as life in the home environment was concerned; 2) rehabilitation for aphasia and perceptual dysfunction proved effective for at least several months after acute stroke; 3) in general, examination of the reports cited revealed no differences in the effects of biofeedback and perceptual retraining vs conventional physiotherapy; 4) rehabilitation, whether administered by specialists or amateur caregivers purpose-trained by specialists, proved equally effective for aphasia. These conclusions constitute a valuable basis for the development and evaluation of modern rehabilitation programs for stroke patients. 相似文献
992.
993.
F. Wellens P. Brugada G. Guiraudon Y. De Grieck R. De Geest H. Vanermen 《European journal of cardio-thoracic surgery》1994,8(12):628-634
Internal cardioverter defibrillator (ICD) implantation has become a standard therapy for life-threatening arrhythmias. A simple and safe surgical implantation technique is therefore mandatory in this high risk population. In a 30-month period 86 patients received 87 ICD devices. An endocavitary lead system was used as first choice in 62 patients and defibrillation thresholds (DFT) of 25 joules (J) or less were obtained in 57 patients. A thoracotomy approach was avoided using a biphasic shock wave form in 17 patients and the addition of a subcutaneous (sc) patch in 11 patients or wire array lead in 9 patients. There was one early non-technique related death (1.7%) after the transvenous approach. Reoperation was necessary in three patients with lead complications and in two patients for local device problems (one migration, one infection). With the recent progress in ICD technology, a thoracotomy approach could be avoided for the last 52 patients. For comfort and cosmetic reasons left subcostal insertion of the device has been successfully used in the last 50 patients. We conclude that the nonthoracotomy approach can now be offered to all patients in need for an ICD as a consequence of the technological progress made in the field of electric treatment of malignant ventricular arrhythmias. A stepwise approach with a minimum of implanted hardware and the use of biphasic shock systems now offers a simple and efficient treatment alternative with very low perioperative risk. Internal cardioverter defibrillator implantation in combination with open heart procedures can easily be avoided. 相似文献
994.
胃癌患者红细胞免疫功能的变化 总被引:4,自引:1,他引:3
运用简单形态学方法测定了30例胃癌患者红细胞免疫功能,结果表明:胃癌患者红细胞C3b受体花环率及肿瘤红细胞花环率显著低于正常对照(P<0.01)及慢性良性胃病患者(P<0.01),而免疫复合物花环率则高于正常人(P<0.01)及慢性良性胃病患者(P<0.01);Ⅲ、Ⅳ期胃癌患者肿瘤红细胞复合物花环率明于低于Ⅰ、Ⅱ期患者(P<0.01);贲门癌肿瘤红细胞花环率显著低于胃窦(体)癌患者(P<0.01) 相似文献
995.
I. Merchenthaler M.D. Culler A. Negro-Vilar P. Petrusz B. Flerko 《Brain research bulletin》1988,20(6):713-720
The gonadotropin-releasing hormone-associated peptide (GAP) and luteinizing hormone-releasing hormone (LHRH) portions of the LHRH precursor were localized by immunocytochemistry in prepubertal female rats, in adult female rats at different stages of the estrous cycle, and in ovariectomized rats. Our results indicate that GAP is present in the same population of neurons as LHRH in the rat brain. These results confirm the specificity of previous immunocytochemical studies which used antisera to LHRH alone. The endocrine status of the animal was demonstrated to affect the immunocytochemical appearance of the GAP system. The number of GAP immunopositive cells and terminals is highest during diestrus II and lowest on the day of estrus, suggesting either a role in and/or a dependence upon the endocrine changes associated with the estrous cycle. Ovariectomy results in a gradual decrease in GAP immunoreactivity in the median eminence. This observation, in concert with other recent studies, suggests that ovarian factors may be acting to maintain the LHRH system and that ovariectomy may result in decreased synthesis and/or processing of the LHRH system and that ovariectomy may result in decreased synthesis and/or processing of the LHRH precursor. 相似文献
996.
丙型肝炎患者外周血单核细胞中丙型肝炎病毒复制的研究 总被引:2,自引:0,他引:2
9例临床诊断为丙型肝炎患者,研究其外周血单核细胞中HCVRNA的存在及复制。9例患者血清标本抗-HCV及HCVRNA均为阳性,采用高敏感的逆转录一套式PCR法测定其外周血单核细胞中HCV正、负链RNA,结果9例患者外周血单核细胞中7例HCV正链RNA阳性,3例HCV负链RNA阳性,证实部分丙肝患者外周血单核细胞中存在HCV的复制,表明肝细胞并非为HCV感染与复制的唯一场所。 相似文献
997.
我国正常中老年人心率变异分析 总被引:10,自引:0,他引:10
心率变异分析(HeartratevariabilityHRV)目前被认为是一项预测心性猝死,特别是预测心肌梗死后病人猝死危险性的独立、敏感的指示。目前尚缺乏大样本HRV时相分析正常值范围。本研究采用英国OXFORD公司MedilogEXCEL长程心电图分析系统,分别用标准差法(Standarddeviation,SD)和HRV指数法(HRVIndex)对120名(男:女=97:23)40一70岁(平均57岁,<60岁者66人,≥60岁者54人)健康人的24小时HRV值进行测算。其结果为,SD:118.15±15.37ms.HRVIndex18.62±2.31;中年组(<60岁)平均SD:;122.03ms.平均HRVIndex:20.16;老年组(≥60岁)平均SD:107。92ms.平均HRVIndex:16.41。两种方法的结果均显示。HRV日间低于夜间,中年人高于老年人,3小时9时HRV最低,与晨间冠心病急性发作事件高峰相吻合。本文并对HRV的昼夜变化规律及其意义进行了初步探讨。 相似文献
998.
人体肥大细胞的多态性已受到广泛关注,对于肥大细胞分型的研究已成为这一问题的关键。本实验研究了42例人大肠4种肥大细胞类群光镜特征,其中两种为作者的新近发现,暂命名为结缔组织肥大细胞-1(CTMC-1)和粘膜肥大细胞-1(MMC-1)。 相似文献
999.
本文应用高效液相色谱与荧光分光光度计联机法检测55例胃液内5-羟色胺的含量,共分为正常、溃疡病、萎缩性胃炎、胃癌等4个组。其结果正常组含量为48.70±49.3ng/ml,溃疡病组含量为76.26±127.06ng/ml,慢性萎缩性胃炎组含量为197.29±128.4ng/ml,胃癌组含量为191.80±124.2ng/ml。4组之间进行对比分析,正常组和溃疡病组之间差异不明显(P>0.05),而萎缩性胃炎和胃癌两组与前两组之间差异均显著(P<0.01),但萎缩性胃炎和胃癌之间未见差异(P>0.05)。这充分证明5-羟色胺(5-HT)在萎缩性胃炎和胃癌的胃液中含量是很高的。对于胃癌和慢性萎缩性胃炎的诊断及与其它慢性胃病的鉴别诊断中可能起到很重要的作用。 相似文献
1000.
本文报告经皮球囊二尖瓣成形术治疗二尖瓣狭窄12例。10例术前平均左房压为18mmHg~40mmHg(26.7±7.15mmHg),术后即刻为4mmHg~18mmHg(10.6±3.86mmHg)P<0.01。跨瓣压差术前10mmHg~40mmHg(19.6±9.05mmHg),术后为0~5mmHg(2.65±2.21mmHg)P<0.01。1例失败,1例术后发生二尖瓣关闭不全急性左心衰竭死亡。 相似文献