密闭液性环境干燥环境下供皮区创面愈合的比较研究

目的比较研究密闭液性环境和干燥环境下供皮区创面的愈合过程. 方法 1996年7月～1997年3月以13例成人断层供皮区创面为研究对象,其中男9例,女4例,年龄20～50岁,创面面积(100～400) cm2,取皮深度中厚,约0.44 mm.同一个创面分为实验组(密闭液性环境)和对照组(干燥环境),采用自身对照法.应用大体、组织学及电镜观察等方法进行观察. 结果密闭液性环境下创面愈合较快,创面组织中成纤维细胞较早活跃、且持续时间较长,再血管化和再上皮化均较早和较快发生. 结论密闭液性环境下创面愈合较快,与组织修复细胞较为活跃、再血管化和再上皮化较快发生有关.     

儿童羟基磷灰石义眼台植入的临床分析

目的:观察儿童羟基磷灰石义眼台植入的临床效果。方法:回顾性分析不同原因造成眼球摘除的31例患儿,其中男性 21例,女性 10例,年龄 3岁～14岁,平均 8.2岁,采用义眼台一期植入 20例,义眼台二期植入 11例,植入直径 18mm义眼台者 17例,植入 20mm义眼台者 14例。结果:31例患儿术后 1例结膜裂开,5例出现轻度上睑沟凹陷,随访 1年～8年,所有患者无感染、无排斥、无义眼台暴露,运动好,外观满意。结论:儿童患者应尽可能一期植入义眼台,采用巩膜包裹义眼台植入的 3岁～6岁患儿选择 18mm直径的义眼台,而 7岁～14岁患儿尽量接近成人选用 20mm直径的义眼台。注意手术操作、术后用药及护理可减少术后并发症。     

Bilateral Hematogenous Pseudomonas aeruginosa Endophthalmitis After Lung Transplantation

Pseudomonas aeruginosa commonly colonizes the airways of patients with cystic fibrosis (CF). However, the occurrence of bacteremia with metastatic infection to the eye causing endogenous endophthalmitis is very rare. In the setting of lung transplantation, the significance of P. aeruginosa bacteremia in patients with CF whose airways are colonized before transplantation is unknown. We report a case of bilateral P. aeruginosa endogenous endophthalmitis in a patient with CF after lung transplant without documented bacteremia. The patient presented with acute eye symptoms in the presence of a left atrial thrombus and the disease followed a rapidly progressive course requiring aggressive medical-surgical treatment. Typically P. aeruginosa endophthalmitis has been associated with a poor visual prognosis. However, with combined medical-surgical management this patient retained useful vision in one eye without having retinal detachment or requiring enucleation. Endogenous endophthalmitis should be considered in the differential diagnosis of ocular complaints in patients with CF after lung transplant.     

湿润烧伤膏在眼部整容术中的应用

目的：为减轻眼部整容术后反应，减少瘢痕形成。方法：采取手术后手法按压止血，伤口涂美宝湿润烧伤膏，冰袋冷敷，提前拆线的方法。结果：所有475例手术者，均提前两天拆线，创口Ⅰ期愈合，无明显瘢痕。结论：美宝湿润烧伤膏有促进伤口愈合，减轻瘢痕形成的作用。     

Toward affordable,sustainable eye care

Adapted from Keynote Addresses to the 5th General Assembly of the International Agency for the Prevention of Blindness, Berlin, Germany, May 9, 1994, and to the International Congress of Ophthalmology, Toronto, Canada, June 29, 1994.     

Anterior eye focusing of peripheral ultraviolet and visible radiation albedo

Concern about short- and long-term ultraviolet radiation (particularly UVB) damage to the eye has led to increased research in this area. Numerous studies have confirmed the pathogenic enhancing roles of reflected ultraviolet (UV) and visible radiation in our environment. There is concern that conventional sunglasses do not protect the eye adequately from reflected rays (albedo), especially on the lateral aspect, from behind and from below. Using eye models and computer ray tracing methods, the pathways of oblique rays incident at the temporal peripheral cornea have been plotted by Maloof, Ho and Coroneo.¹ These rays are refracted and focused and theoretically can result in up to 20 times the concentration of incident irradiance at the nasal anterior chamber angle and nasal equatorial cortex of the crystalline lens. The purpose of this study was to determine the limits of angular subtense of the incident peripheral light which is refracted in this manner in human subjects and to investigate the relation between corneal shape and certain ocular parameters to the limits. A statistically significant positive correlation was found between temporal entrance angle and anterior chamber depth (r = 0.70, P< 0.0006). The entrance angle ranged from 15 degrees to 30 degrees and was located 10 degrees to 45 degrees posterior to the coronal plane. Our results support Maloof and colleagues' predictions for the implication of focused peripheral UV and high intensity visible radiation in the pathogenesis of pterygium and cortical cataract and emphasise the need for lateral eye protection in conditions of high ultraviolet albedo.     

氟康唑滴眼液的研制及临床应用

介绍氟康唑滴眼液的制备方法，质量标准、刺激性试验及治疗真菌性角膜溃疡，应用结果表明：制剂设计合理，水溶液稳定性好，无刺激性、疗效确切、工艺简单，适合医院制剂室配制。     

恩施土家族人眼的表面形态特征

按随机抽样原则选择湖北恩施土家族人５９８名观测了眼的表面形态。该民族大部分人两眼位置适中，虹膜褐色，眼裂水平，开度中等，无蒙古褶，双睑；多为细窄眼型或中等眼型；眼的各径男大于女，一般存在性别差异；随年龄增加，眼型由中等型向细窄型转化，根据眼外形特征和聚类分析推测，土家人眼属于南、北方民族间的过渡型。     

金珠滴眼液治疗慢性结膜炎的临床研究

目的　探讨金珠滴眼液治疗慢性结膜炎的疗效。方法　将慢性结膜炎患者 36例 6 8眼随机分为2组 ,每组 34眼 ,实验组用 7.8%金珠滴眼液点眼治疗 ,对照组用 0 .2 5 %氯霉素点眼治疗。结果　金珠滴眼液1、2、4周疗效的综合分值判定均与对照组有显著差异 (P <0 .0 5 ) ,且无局部刺激性。结论　金珠滴眼液对慢性结膜炎有明显的治疗作用 ,可望为临床常见多发的慢性结膜炎患者消除或缓解症状     

明胶海绵替硝唑浸湿剂预防干槽症临床研究

目的　探讨在拔除下颌阻生齿后 ,采用明胶海绵替硝唑浸湿剂置于牙槽窝内是否在预防干槽症中发挥作用。方法　临床上随机选择A、B两组下颌第三磨牙拔除的病人 ,每组 10 0例 ,A组为拔除下颌阻生齿后缝合不做其他处理 ,B组在拔牙后应用明胶海绵替硝唑浸湿剂置于拔牙创内并缝合。结果　A、B两组在拔牙后 4 8～ 72h无显著差异 ,在 72h后发生干槽症上A组明显大于B组 (P <0 .0 5 )。结论　明胶海绵替硝唑浸湿剂有明显的预防拔牙术后发生干槽症的作用。