益气活血复方与复方丹参制剂治疗心绞痛疗效的系统评价

目的系统评价益气活血复方与复方丹参制剂治疗冠心病心绞痛的疗效和安全性。方法两名作者独立收集资料和评价纳入文献质量,采用RevMan4.2.2软件对资料进行Meta分析。结果①对20项研究的临床疗效有效率合并效应量的检验：OR合并=3.74,其95%CI为[2.58,5.43],P〈0.01;②对18项研究的心电图疗效有效率合并效应量的检验：OR合并=2.29,95%CI为[1.85,2.83],P〈0.01。结论益气活血复方治疗冠心病心绞痛的疗效优于复方丹参制剂,且不良反应少。     

神经元在丝素蛋白材料上的生长发育

目的研究神经元在丝素蛋白材料上的生长发育,为神经干细胞结合丝素蛋白材料用于临床移植修复神经系统损伤提供实验依据。方法从新生大鼠脑室下区（SVZ）分离细胞,培养在柞蚕、家蚕两种丝素蛋白溶液制成的薄膜材料上,分别选取各时间段的细胞进行β-Ⅲ-tubulin特异性免疫荧光染色,并统计不同时间段神经元在丝素材料上的成活率及复杂度。结果神经元在柞蚕丝素薄膜上的成活率和复杂度明显比家蚕丝素薄膜高,差异均有统计学意义（均P〈0.05）。结论柞蚕、家蚕丝素薄膜支持神经元的生长,具有良好的生物相容性;柞蚕丝素薄膜比家蚕丝素薄膜更适合神经元的生长。     

玉米须在肝胆系统疾病的应用

玉米须(Corn Silkor Stigma Maydis)是一种物美价廉的药物,其"味甘、淡,性微温",玉米须含有多种有效化学成分,具有降糖、降压、降脂,抗菌,利胆、排石,止血,抗肿瘤,提高免疫力等药理作用,目前应用于临床治疗多种疾病。现仅就玉米须在肝胆疾病方面应用作综合讨论。     

Clinical effectiveness of a silk fabric in the treatment of atopic dermatitis

BACKGROUND: In children with atopic dermatitis (AD), eczema is easily aggravated by contact with irritant factors (e.g. aggressive detergents, synthetic and woollen clothes, climatic factors). OBJECTIVES: To evaluate the effectiveness of a special silk fabric (MICROAIR DermaSilk) in the treatment of young children affected by AD with acute lesions at the time of examination. METHODS: Forty-six children (mean age 2 years) affected by AD in an acute phase were recruited: 31 received special silk clothes (group A) which they were instructed to wear for a week; the other 15 served as a control group (group B) and wore cotton clothing. Topical moisturizing creams or emulsions were the only topical treatment prescribed in both groups. The overall severity of the disease was evaluated using the SCORAD index. In addition, the local score of an area covered by the silk clothes was compared with the local score of an uncovered area in the same child. All patients were evaluated at baseline and 7 days after the initial examination. RESULTS: At the end of the study a significant decrease in AD severity was observed in the children of group A (mean SCORAD decrease from 43 to 30; P = 0.003). At the same time, the improvement in the mean local score of the covered area (from 32 to 18.6; P = 0.001) was significantly greater than that of the uncovered area (from 31 to 26; P = 0.112). CONCLUSIONS: The use of special silk clothes may be useful in the management of AD in children.     

Effects of cooking fuel smoke on respiratory symptoms and lung function in semi-rural women in Cameroon

Abstract

Atrazine, an herbicide used on most of the US corn (maize) crop, is the subject of ongoing controversy, with increasing documentation of its potentially harmful health and environmental impacts. Supporters of atrazine often claim that it is of great value to farmers; most recently, Syngenta, the producer of atrazine, sponsored an “Atrazine Benefits Team” (ABT) of researchers who released a set of five papers in 2011, reporting huge economic benefits from atrazine use in US agriculture. A critical review of the ABT papers shows that they have underestimated the growing problem of atrazine-resistant weeds, offered only a partial review of the effectiveness of alternative herbicides, and ignored the promising option of non-chemical weed management techniques.

In addition, the most complete economic analysis in the ABT papers implies that withdrawal of atrazine would lead to a decrease in corn yields of 4·4% and an increase in corn prices of 8·0%. The result would be an increase in corn growers’ revenues, equal to US$1·7 billion annually under ABT assumptions. Price impacts on consumers would be minimal: at current levels of ethanol production and use, gasoline prices would rise by no more than US$0·03 per gallon; beef prices would rise by an estimated US$0·01 for a 4-ounce hamburger and US$0·05 for an 8-ounce steak. Thus withdrawal of atrazine would boost farm revenues, while only changing consumer prices by pennies.     

Standardisation of thrombin generation test - which reference plasma for TGT?: An international multicentre study

We have previously shown that standardisation and normalization of results improve the intercentre variability of the calibrated automated thrombin generation test (TGT). We suspected that the source of reference plasma (RP) might be a contributing factor to variability and compared 5 commercial RP and a RP provided by the NIBSC, in an international, multicentre study. The detailed composition of the 6 tested plasma samples was determined in the Haemostasis Labotatory in Lyon. The lot to lot consistency, intra-assay, inter-assay variability were calculated for all tested plasmas. The RP and 3 plasma samples (a normal control, a hypocoagulable and a hypercoagulable plasmas) were tested over 6 days, in 5 European centres. Results were normalised against each of the tested RP and intercentre variability of results was compared. All laboratories used the same reagents. Before normalization, the inter-centre variability was 19.8 to 27.3%. After normalization, we observed a significantly improved inter-laboratory variation with all tested RP, despite differences between them. These results clearly demonstrate that the inter-centre variability of TGT can be significantly reduced by using a reference plasma normalization, and that certain RP have a better capacity to reduce this variability than others.     

羟基磷灰石/丝素蛋白复合多孔材料的制备及其表征***☆

摘要：以蚕丝丝素蛋白作为羟基磷灰石沉积的模板，制备羟基磷灰石/丝素蛋白复合凝胶，以此为基体，分别以蚕丝短纤维和NaCl颗粒作为增强材料和致孔剂，采用等静压成型法，制备羟基磷灰石/丝素蛋白多孔复合材料。对复合材料结构和力学性能的研究结果表明，材料中含有少量蚕丝短纤维对材料抗弯强度和断裂能力的提高有显著效果，以NaCl颗粒为致孔剂可使材料的平均孔径及孔隙率分别在64~183 µm及55%~75%范围内调节。 关键词：羟基磷灰石；丝素蛋白；多孔材料；复合材料；增强材料     

煤烟型氟中毒地区玉米氟卫生标准的研究

根据煤烟型氟中毒地区环境流行病学调查和高氟煤烟污染玉米的毒理学研究结果,提出了适用于我国煤烟型氟中毒地区玉米氟的卫生标准,即最高容许限量为2mg/kg。     

玉米不同播种期对生长发育和产量性状的影响

以玉米杂交种桂顶一号,于1988～1989年在广州作分期播种试验。结果表明,全生育期、产量、株高和果穗位高受播期的影响较大,变化差异明显,而植株总叶片数和果位高/株高比值的变化较小。全生育期以2～3月和9月播种的较长,4～8月播种的较短。产量以3～4月上旬和7、8、9月播种的较高,5～6月播种最低。影响生育期长短的主要因子是温度条件,较低温延长生育,较高温促进生育,从而影响产量。构成产量的主要性状,以千粒重和行粒数变化最大,与产量相关最密切。