口疮病患者唇微循环的变化

目的：观察口疮病唇循环的变化，从微循环角度为其发病机理提供依据。方法：对63名患者及50名健康人采用微循环显微镜，常规检查下粘膜近红部位，按田牛加权积分法并参考甲襞微循环评分标准对21项指标进行分析。结果：口疮病患者唇微循环中度异常，积分值高于正常组。结论：口疮病患者有微循环障碍，这可能是其发病机理之一，采取改善微循环的措施，对治疗有所裨益。     

艾灸对30例健康人甲皱微循环及血液流变学的影响

目的：探讨艾灸对健康人甲皱微循环及血液流变学的影响。方法：选择健康学员及武警战士各30例，年龄20－22岁，应用江苏协达公司生产的XDM－1型微循环电脑检测仪及北京世帝科学仪器公司生产的LG－R－80血液粘度计，LG－B－190型红细胞变形／聚集测试仪。固定专人操作，分别于艾灸前及艾灸后，测试甲皱微循环及血液流变学各项指标的变化。结果：艾灸八邪及三阴交穴后，甲皱微循环各项指标均有明显变化，经统计学处理，红细胞聚集程度、血流速度、流态积分、管周积分均有显著性差异（P＜0．05），其余各项指标虽有不同程度的改变，但无统计学意义（P＞0．05）；血液流变学各项指标亦有明显变化，经统计学处理，全血低切相对粘度、全血低切还原粘度、红细胞刚性指数、红细胞聚集指数及血浆纤维蛋白原都有非常显著性差异（P＜0．01），全血高切相对粘度有显著性差异（P＜0．05），其余各项指标虽有不同程度的改变，但无统计学意义（P＞0．05）。结论：艾灸八邪及三阴交穴后可明显改善红细胞聚集程度，降低血液粘度，加快血流速度，降低外周血管阻力。     

奥扎格雷钠联合小剂量尿激酶治疗急性脑梗死的疗效观察

目的 观察奥扎格雷钠联合小剂量尿激酶治疗急性脑梗死的疗效.方法 选择颈内动脉系统急性脑梗死患者107例,随机分成2组,治疗组54例,对照组53例.治疗组奥扎格雷纳80mg加入生理盐水250ml静滴,1次/d,连用10d;尿激酶20万U加入生理盐水200ml静滴,1次/d,连用7d.对照组血塞通500mg,曲克芦丁0.6g分别加入生理盐水250ml中静滴,1次/d,连10d.治疗前后监测FG、PLT、PT、APTT、GPT、BUN.结果 治疗组总有效率90.74%,对照组75.47%.治疗后2组间神经功能缺损评分、总有效率有显著性差异,治疗组治疗前后PT、APTT、FG、GPT、BUN无变化.结论 奥扎格雷钠联合小剂量尿激酶治疗急性脑梗死安全有效.     

试论手法之补泻及其辨证应用

本文通过古代文献论述以及现代研究,提出了手法补泻的方向、缓急、轻重、时间、手法和受力部位和特性的六个影响因素,并以以"三因制宜"为纲,从因地、因时、因人的年龄、性别、体质、所患疾病、病情变化、脏腑功能、耐推拿程度以及心量状况的不同等十个方面论述手法之补泻的临床辨证施用.     

情绪性疾病知多少

我们知道，人感染了细菌、病毒会得病，机体受了创伤会发病，饮食不当也会患病，却往往忽视了另一种非常常见，却又不足以引起人们注意的致病因素，这就是不正常的情绪变化，它可能导致很多疾病发生，下面这些疾病皆可由不良的情绪所致。     

优化商品陈列 刷新销售业绩

研究表明：商品陈列面的大小变化、化妆品陈列的高低变化和化妆品的陈列时间等均会影响化妆品店的销售额。首先，商品陈列面的大小变化会引起销售额的变化。如由4个货位减少到2个货位，销售额锐减48％；由3个货位减少到1个货位，销售额锐减68％；由2个货位增加到4个货位，销售额增加40％。所以，在化妆品店的商品陈列中，要加大购买频率较高品种的陈列面，并以大陈列面形成聚焦点，刺激顾客购买。     

血透患者中枸橼酸西地那非的药代动力学及血流动力学变化

患有肾病的男性中ED发病率很高。枸橼酸西地那非是勃起功能障碍的高效治疗药物，严重肾功能不全会使该药清除率下降，但在血透治疗的终末期肾病患者中，该药的药代动力学和血液动力学研究尚未见报导。为了研究血透患者中，该药的药代动力学和血流动力学变化，Grossman EB等人让15例慢性门诊血透维持患者在血透前2h及血透后2h口服单剂西地那非，先服哪一次进行随机分配确定。     

Changes in T .lymphocyte subsets after severe traumatic brain inJury

BACKGROUND： Besides local changes of cranial parenchymal cells, hemorrhage, etc., severe traumatic brain injuries also cause the changes of total body fluid and various functions, and the changes of lymphocytes and T lymphocyte subsets should be paid more attention to. OBJECTIVE： To reveal the changing laws of T lymphocyte subsets after severe traumatic brain injury, and compare with mild to moderate brain injury. DESIGN： A comparative observation. SETTINGS： Department of Neurosurgery, Longgang District Buji People＇s Hospital of Shenzhen City; Central Laboratory of Shenzhen Hospital of Prevention and Cure for Chronic Disease. PARTICIPANTS： All the subjects were selected from the Department of Neurosurgery, Longgang District Buji People＇s Hospital of Shenzhen City from August 2002 to August 2005. Thirty patients with severe brain injury, whose Glasgow coma score （GCS） was ≤ 8 points, were taken as the experimental group, including 21 males and 9 females, aging 16 - 62 years. Meanwhile, 30 patients with mild traumatic brain injury were taken as the control group （GCS ranged 14- 15 points）, including 18 males and 12 females, aging 15 -58 years. All the subjects were in admission at 6 hours after injury, without disease of major organs before injury Informed consents were obtained from all the patients or their relatives. METHODS： （1） The T lymphocytes and the subsets in peripheral blood were detected with immunofluorescent tricolor flow cytometry at l, 3, 7 and 14 days after injury in both groups. （2） The conditions of pulmonary infections were observed at 4 days after injury. The differences of measurement data were compared with the t test. MAIN OUTCOME MEASURES： Changes of T lymphocytes subsets at 1 - 14 days after severe and mild or moderate traumatic injury. RESULTS： Finally, 28 and 25 patients with mild to moderate traumatic brain injury, whereas 25 and 21 patients with severe traumatic brain injury were analyzed at 7 and 14 days respectively, and the missed ones died due to the development of disease. （1） Changes of T lymphocyte subsets： At 1 and 3 days after injury, CD3, CD4, CD8, CD4/CD8 began to decrease, whereas CD8 increased in the experimental group, which were very significantly different from those in the control group （t =2.77 - 3.26, P 〈 0.01）, and began to recover at 7 days, which were significantly different from those in the control group （t = 2.06 - 2.24, P 〈 0.05）, and generally recovered to the normal levels at 14 days （P 〉 0.05）. （2） Conditions of pulmonary infections： At 4 days after injury, the rate of pulmonary infection was significantly different between the experimental group and control group [73% （22/30）, 0, x2=37.29, P 〈 0.01]. CONCLUSION： Patients with severe traumatic brain injury suffer from damages of cellular immune function at early period （within 7 days）, and they are easily to be accompanied by pulmonary infections.