创新发展思路 突出学科建设 打造特色中小医院

本文作者介绍了创新发展模式、突出学科建设、打造特色中小医院方面的经验做法：着眼战场，适应市场，确立“特色建科、技术强科、人才兴科”的发展思路，有所为有所不为，把特色专科做大做强做精，在打造特色中小医院上下功夫、见成效，实现医院全面建设的突破性进展。     

Raisins are a low to moderate glycemic index food with a correspondingly low insulin index

The objective of this study was to determine the glycemic index (GI) and insulin index (II) of raisins and evaluate if these values are similar in different populations. The study subjects consisted of 10 healthy sedentary individuals (S; age, 25.7 ± 1.3 years; body mass index [BMI] = 23.3 ± 1.7 kg/m²), 11 aerobically trained adults (A; age, 23.1 ± 1.0 years; BMI = 24.1 ± 0.3 kg/m²), and 10 prediabetic adults (P; age, 50.0 ± 2.6 years; BMI = 32.6 ± 1.9 kg/m²). Subjects consumed 50 g of available carbohydrate from raisins and from a glucose solution (reference food) on 2 separate occasions. Serum glucose and insulin concentrations were measured from capillary fingerstick blood samples at baseline and at 15, 30, 45, 60, 90, and 120 minutes (and 150 and 180 minutes for P group) postprandially. The GI of raisins was low (GI, ≤55) in the S (49.4 ± 7.4) and P (49.6 ± 4.8) groups and was moderate (GI, 55-69) in the A group (62.3 ± 10.5), but there were no differences among the subject groups (P = .437). The II of raisins was 47.3 ± 9.4, 51.9 ± 6.5, and 54.4 ± 8.9 for the S, A, and P groups, respectively. On average, the A group secreted 2- to 2.5-fold less insulin per gram of carbohydrate compared with the S and P groups (P < .05). Thus, raisins are a low to moderate GI food, with a correspondingly low II. The lower insulin response in the A group compared with the other groups suggests enhanced insulin sensitivity.     

论食品卫生行政执法中不移送案件的刑事责任

食品卫生行政执法主体及时移送涉嫌犯罪的案件是保护食品安全的要求。故意不移送，情节严重的，则会构成徇私舞弊不移交刑事案件罪；负有追究责任的国家机关工作人员徇私舞弊，不履行法律规定的追究职责，情节严重的，则会构成放纵制售伪劣商品犯罪行为罪。     

Peripheral-type benzodiazepine receptors on platelets are correlated with the degrees of anxiety in normal human subjects

RATIONALE: Anxiety is the one of the main symptoms of psychiatric disorders. Psychosocial stressors have been shown to be related to the onset of anxious episodes. Peripheral-type benzodiazepine receptors (PBR) are involved in regulating stress responses. The sensitivity of PBR to acute or chronic stress has been demonstrated in various situations. The State-Trait Anxiety Inventory (STAI) is one of the longest standing and most frequently used measures of anxiety. The development, evaluation, and use of biological markers with anxious conditions in psychiatry are extremely important. OBJECTIVES: The aims of this survey are to see whether PBR can be used in screening the degrees of anxiety which occur when normal persons are placed in the stressful conditions. METHODS: Twenty-four healthy volunteers (14 men, 10 women; mean age 46 years) participated in this study. We administered the STAI to all the volunteers. The binding of the radioactive PBR antagonist [(3)H]PK 11195 to platelet membranes was determined for these volunteers. RESULTS: The mean STAI scores were 40.3+/-8.0 for trait anxiety and 39.0+/-8.9 for state anxiety. B(max) of the platelet PBR binding was 2845+/-2109 fmol/mg protein. Pearson correlational analyses revealed that B(max) values were significantly and positively correlated with scores for trait anxiety but not significantly correlated with scores for state anxiety. CONCLUSIONS: PBR on platelets are correlated with trait anxiety scales of the STAI in healthy normal subjects. It is therefore suggested that the density of platelet PBR is highly associated with these personality traits for anxiety tolerance. PBR density in platelet could also be used as a promising biological marker of stressful conditions.     

Analysis of ulcer data using hierarchical generalized linear models

In multi-centre clinical trials, heterogeneities in individual hospital treatment effects can be modelled as random effects. Estimates of the individual hospital treatment effects and estimate of the mean treatment effect, allowing for the presence of overall hospital differences, are required, together with some measure of their uncertainty. Systematic inferences from the hierarchical-likelihood are now possible, using hierarchical generalized linear models. We show how to construct profile likelihoods for the treatment effects of individual hospitals.     

医学院校"信息管理与信息系统"专业课程设置

医学“信息管理与信息系统”专业培养目标是在医药卫生领域，既能够从事信息资源管理、又能够进行信息系统开发和设计的文、理、工兼备的复合型高级专门人才。该专业的定位是信息技术如何为管理服务或管理中如何应用信息技术。课程设置不但要从专业的理论背景和学术角度考虑，更重要的是还要从就业角度考虑，主要课程分为4个版块：医药学基础，教学，计算机，信息与管理。计算机课程在本专业中有着举足轻重的住置，其中的程序类课程是关键课程。     

心血管内科学科技术发展历程与思考

近年,心血管病治疗领域的快速进展,主要得益于以心导管为基础的介入治疗和循证医学大规模临床试验的开展。心血管病介入治疗是发展最为迅猛的学科技术之一。我国目前已能通过介入治疗治愈绝大部分以前只能外科手术治疗的心脏病变。沈阳军区总医院开展的左冠脉主干病变经皮冠状动脉介入治疗(PC I)和冠脉慢性完全闭塞(CTO)病变PC I的完成例数及成功率均达到国际领先水平。在以下几方面应大力加强:包括冠心病、高血压的预防及重度心衰的治疗,筛选冠心病易感基因及易感人群,并探讨加强其防治对策的研究;药物洗脱支架扩大样本量,增加随访观察时间;进一步深化心肌再生和血管再生研究,以改善缺血性心肌病患者的预后;深化PC I术后抗血小板治疗的研究,探讨抗血小板药和其他常用心血管药物(如调脂药)之间的关系、抗血小板药物抵抗产生的原因、诊断方法及治疗对策等。     

信息化条件下军队医院临床学科质量控制评价指标体系研究

目的：构建军队医院临床学科质量控制评价指标体系以硬评估模型,为改进临床学科质量控制模式提出了政策建议。方法：采用专家咨询法和层次分析法建立军队医院临床学科质量控制评估指标体系,运用综合评价法构建评估模型。结果：某战区所属各医院和临床部临床学科质量控制模式科学性好,可操作性强,质控效能高。结论：指标体系内容完善,制定合理,实用性强。     

外周血T淋巴细胞亚群与非小细胞肺癌临床病理特征相关的研究

目的　探讨非小细胞肺癌 (NSCLC)患者外周血T淋巴细胞亚群的分布及其与临床病理特征的关系。方法　分离 40例NSCLC患者外周血单个核细胞 ,采用间接免疫SPA法测定T淋巴细胞亚群的分布状况。结果　CD3、CD4 阳性百分率及CD4 CD8比率在Ⅰ～ⅢA 期均高于ⅢB、Ⅳ期 (P <0 .0 5 )。病理分化Ⅰ、Ⅱ级均分别高于Ⅲ级 ;CD8则相反 ,且差异均有显著性 (P <0 .0 5 ) ;鳞癌与腺癌差异均无显著性 (P >0 .0 5 ) ;术后及放疗后 3月 ,CD3、CD4 阳性百分率及CD4 CD8比率与治疗前差异无显著性 (P >0 .0 5 )。手术加放疗后或加放疗后 3个月CD3、CD4 阳性百分率及CD4 CD8比率与治疗前比较均下降 ,CD8则相反 (P <0 .0 5 )。 1年内复发转移者CD3、CD4 阳性百分率及CD4 CD8比率与治疗前比较差异无显著性 (P >0 .0 5 )。结论　T淋巴细胞亚群与NSCLC不同病期及分化程度相关 ,动态观察有助于估计预后 ,指导治疗     

试探中医理论实验课的特点和任务

从中医理论的实验课的内涵及实验课特点出发来阐述中医实验课的任务,强调中医理论实验课有很强的中国文化特征.