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51.
Yosi Wibowo Ph.D Adji P. Setiadi Dr. Steven V. Halim M.Pharm. Rama D. Saputra B.Pharm. Rizka Oktavia B. Pharm. Rizky Irianti B. Pharm. Putri I. Lestari B. Pharm Cecilia R. Puspitasari B.Pharm. Bruce Sunderland Ph.D. 《Health & social care in the community》2021,29(2):554-563
In 2015, the Indonesian Government initiated ‘Smart Use of Medications Movement’ (‘GeMa CerMat’) which included cadre training to promote responsible self-medication. Evaluation of a pilot training conducted across Indonesia suggested the need to improve those training modules. This study aimed to assess cadre’ knowledge gained following training with newly developed general or specific training modules. Five types of modules were developed and used to train cadres at five Community Health Centres (CHCs) in Surabaya, Indonesia: 1) Sidosermo CHC (general-drugs module), 2) Tenggilis CHC (common cold drugs module), 3) Gunung Anyar CHC (analgesic drugs module), 4) Kalirungkut CHC (anti-diarrhoeal drugs module), and 5) Jagir CHC (indigestion drugs module). Cadres’ knowledge improvements were evaluated using pre-/post-test scores and the difference scores depending on the module being tested. Multifactorial ANOVA explored the effects of the type of module on difference scores. A total of 279 cadres across five CHCs were involved in the training, giving response rates from 65% to 93%. There was an increase in the post-test scores after the training with all modules. However, significant differences were reported only for the specific-drugs module groups (all p < .001). Furthermore, the general module group had the lowest difference score (1.12; 95% CI [−0.45, 2.92]) while the common cold module group had the highest gain (5.02; 95% CI [1.95, 5.17]). Multifactorial ANOVA revealed that there was a significant main effect of the type of modules on difference scores [F (4, 263) = 8.37, p <.001]. In conclusion, this preliminary study indicated that the development of modules for specific minor illnesses could be beneficial in facilitating effective community-based training to promote responsible self-medication in Indonesia. The priority for therapeutic areas chosen for the module should be based on the local needs. Further research is required to confirm the findings in broader community members. 相似文献
52.
目的 观察羟基喜树碱(HCPT)和5-氟脲嘧啶(5-Fu)联合化疗治疗晚期胃肠道肿瘤的近期疗效和毒副反应。方法HCPT10mg/d,静脉点滴,连用10天;5-Fu0.75mg/d,静脉点滴年,连用5天。21天为-个周期,二至三个周期观察疗效。结果20例胃癌CR1例,PR9例,NC6例,PD4例,总有效率(CR PR)为50%;结肠癌15例中CR2例,PR6例,NC5例,PD2例,(CR PR)为53.3%。毒副反应多为胃肠道反应及骨髓毒性,多为1~2级。结论以HCPT和5-Fu联合治疗晚期胃肠道肿瘤疗效较好,且毒副反应可以耐受。 相似文献
53.
HFJV联合药物治疗兔海水淹溺肺水肿 总被引:2,自引:0,他引:2
目的:观察高频喷射通气(HFJV)联合4种药物治疗海水淹溺肺水肿(PE-SWD)的效果并探讨其作用机制。方法:用海水灌注的方法诱导PE-SWD模型,采用HFJV联合地塞米松、东莨菪碱、尼莫地平和果糖二磷酸钠4种药物进行治疗,观察记录相关的生理、生化指标。结果:HFJV联合4种药物治疗能明显改善PE-SWD相关指标。结论:HFJV联合4种药物治疗能有效治疗PE-SWD,可作为其基础治疗。 相似文献
54.
The number of child psychiatrists, paediatricians and general practitioners prescribing psychotropic medication for children in the UK is increasing. Medication is being used not just to treat children of normal intelligence with hyperkinetic disorder or depression, but also to modify behavioural problems in children with developmental disorders and severe learning difficulties. Literature reviews highlight the lack of robust randomized controlled drug trials on which to base clinical practice and the authors have found no appropriate existing protocols to help develop a systematized approach. Against such a background the authors have developed a comprehensive set of protocols covering prescribing details for individual drugs, and also addressing issues such as informed consent, long-term monitoring and school liaison. All children referred to the authors' clinics go through a standardized decision-making process. This article describes both the protocols themselves and the philosophies that guided their development. The authors describe how such a system benefits the children, their families, general practitioners and schools, whilst also facilitating audit and research. 相似文献
55.
目的 观察多巴酚丁胺与复方丹参注射液联合应用治疗肺心病心衰的疗效; 方法 在综合治疗的基础上,将多巴酚丁胺20mg 加入10% 的葡萄糖250ml 中静滴, 复方丹参注射液16ml 加入10% 的葡萄糖250ml 中静滴,每日一次,7 日为一疗程,所获数据经卡方检验; 结果 治疗组显效21 例,有效8 例,总有效率90.6 %( X2 =9 .36,P<0 .05),与对照组比较,有显著性差异; 结论 改善肺微循环,提高心肌收缩力,减轻心脏负荷有助于肺心病心衰的纠正。 相似文献
56.
Friedrich Gönner Ralf Baumgartner Daniel Schüpbach M. C. G. Merlo 《Psychopharmacology》1999,144(4):416-418
Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal side-effect of antipsychotic drug therapy, especially
of dopamine receptor antagonists. As a dose relationship has been postulated, low dose neuroleptization would be expected
to help to avoid this side-effect. In contrast, we report on a 21-year-old female following low dose fluphenazine treatment
with 2.5 mg/day. The patient recovered from NMS after 3 days of dantrolene administration. Eventually, remission from psychotic
symptoms was achieved with clozapine. At 8-month follow-up, psychopathology remained stable and there were no more signs of
NMS.
Received: 8 July 1998 / Final version: 6 November 1998 相似文献
57.
目的:统计分析我院消化科作用于消化系统药物用药情况,提高临床合理用药水平。方法:应用电脑统计2002年9月4日~2003年5月6日我院消化科用药有效数据,采用金额排序法和DDDs排序法,对作用于消化系统药物进行统计分析。结果:用药金额和DDDs最高的是抗酸药及治疗消化系溃疡药类,具体药物是奥美拉唑。结论:我院消化科对作用于消化系统药物的使用基本合理。 相似文献
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