威海矿泉浴对心电图血压微循环心率的综合影响动态观察

目的 研究威海矿朱浴对冠心病等心血管疾病病人的作用机理。方法 水温３９℃浸浴时间１０分钟，被测试的病人一律地浴前测心电图、血压、微循环、脉搏，出池１５分钟内测心电图、血压、微循环、脉搏。结果 浴前心电图异常者７０例，浴后改善者２２例，占３１．４％，无变化者４６例，占６５．７％，恶化者２例，占２．９％；高血压病人７５％的在浸浴后，血压下降１ｋＰａ以上；微循环测试１００％改善。结论 矿泉浴改善微循环，     

SEM,EDX and EIS study of an electrochemically modified electrode surface of natural enargite (Cu3AsS4)

Enargite electrodes, made from mineral originating in the ‘Salvador’ mine (Chañaral, Chile), have been studied using SEM, EDX, CV and EIS in an alkaline solution for a range of different potentials in the positive sweep direction (PSD) and negative sweep direction (NSD). The results of SEM and EDX have shown that the principal changes in morphology and chemical composition take place on the surface of the electrode for oxidation potentials close to the value that corresponds to the most intense peak in the PSD, where there is clearly formation of a layer of oxidised material with areas of morphology which are irregular and high in oxygen content. These results are in accordance with the findings from XPS studies published previously. The charge transfer resistance and the resistance of the anodic layer of the electrode were determined by EIS measurements; the values depend heavily on the applied potential in the PSD or NSD. These changes are related to the changes on the surface of the electrode studied by SEM and EDX     

PULPOTOMIES WITH PORTLAND CEMENT IN HUMAN PRIMARY MOLARS

Two clinical cases in which Portland cement (PC) was applied as a medicament after pulpotomy of mandibular primary molars in children are presented. Pulpotomy using PC was carried out in two mandibular first molars and one mandibular second molar, which were further followed-up. At the 3, 6 and 12-month follow-up appointments, clinical and radiographic examinations of the pulpotomized teeth and their periradicular area revealed that the treatments were successful in maintaining the teeth asymptomatic and preserving pulpal vitality. Additionally, the formation of a dentin bridge immediately below the PC could be observed in the three molars treated. PC may be considered as an effective alternative for primary molar pulpotomies, at least in a short-term period. Randomized clinical trials with human teeth are required in order to determine the suitability of PC before unlimited clinical use can be recommended.     

Plasma and erythrocyte levels of trace elements and related antioxidant enzyme activities in low-birthweight infants during the early postnatal period

To discover the relationship between antioxidant enzyme activities and trace elements in lowbirthweight infants during the early postnatal period, we analysed catalase (CAT), CuZnsuperoxide dismutase (CuZn-SOD) and glutathione peroxidase (GSH-Px) activities in erythrocytes, and compared them with Fe, Cu, Zn and Se levels in plasma, and Cu, Zn and Se levels in erythrocytes until 16 wk after birth. Thirteen low-birthweight infants whose mean birthweight and gestation were 1520 ±293 g and 32.0 ±2.8 wk were enrolled in this study. All infants were without chronic complications, well nourished, and predominantly fed standard formula or preterm formula based on cow's milk, commercially available in Japan. Cu and Zn levels in erythrocytes did not decline after birth, in contrast to a temporal decrease in plasma Zn. Erythrocyte CAT activity was significantly higher at 16 wk than that at birth or 4 wk of age. Erythrocyte CuZn-SOD activity did not change throughout the study period. Only Se in plasma and erythrocytes decreased remarkably after birth, which resulted in a significant decline in erythrocyte GSH-Px activity at 8 and 16 wk (11.2 ±2.0 and 11.0 ±1.1 U/g Hb) compared to that at birth (12.4 ±2.1 U/g Hb).

Conclusion: During the early postnatal period, erythrocyte CAT and CuZn-SOD activities did not decrease in formula-fed, low-birthweight infants. Japanese commercial formula not supplemented with Se, however, caused postnatal plasma and erythrocyte Se deficiency and a concomitant decline in erythrocyte GSH-Px activity in the same subjects.     

恩施地区硒茶的元素及元素结合态分析

硒元素对人体健康起着重要的作用。随着中国两个高硒区 (湖北恩施和陕西紫阳县 )的发现 ,这些地区所产富硒茶作为缺硒地区的硒补充源愈来愈引起人们的关注 [1] 。茶叶中硒和其它元素含量及其结合形态已有研究报告[2 ,3 ] 。但迄今为止 ,尚未见有关茶汤中硒结合态的公开报道。　　全反射 X射线荧光法是自 1 971年发展起来的现代多元素分析方法。因其具有检测限低、灵敏度高、精度和准确度高、定量简单 (同时测定 2 5个元素只需一个内标元素 )、操作方便、日常消耗费用低等优点 ,近年来在食品、化工、材料、环境、医学等许多领域得到了广泛的…     

角膜缝合操作规划

角膜缝合操作是角膜移植手术成功的关键。首先，本文通过分析角膜的缝合操作过程，建立了角膜移植手术中缝合过程的几何模型。在不考虑角膜组织粘弹性的条件下，进行了单个缝合过程的路径规划。在此基础上，考虑角膜组织缝合过程中的弹性，利用有限元分析软件ANSYS，对角膜缝合过程进行了模拟，规划了缝针在角膜组织变形条件下的工作路径，并计算出了缝针在缝合过程中的位置与姿态变化曲线。此研究可用于指导角膜缝合机器人完成缝合操作任务。     

Effect of washing mineral oil on development of mouse embryos in vitro and in vivo after embryo transfer

Objective:To establish a simple and effective washing procedure for both used and purchased mineral oil,that can be used for embryo culture.Methods:A complete test system has been used for this purpose.There are 3 steps in our new washing proto-col.First,the oil was mixed with 95% ethanol at 1:1,the bottle being shaken by hand for 10 minutes,then sepa-rated.Second,the oil was heated to boiling point with 0.31 mol/L NaCl for 30 minutes.Third,anhydrous Na:SO4 was put into the oil for further treatment.1-cell stage embryos of a KM strain mouse have been collected surgically and cultured.Cleavage and blastocyst stage development were recorded and some embryos were transferred into re-cipients.Results:The results show that recycled oil can promote the development from 2-cell to blastocyst stage(23.3%)when compared with that of control(16.9%).Offspring have been obtained at 44 %(7/16),16 %(3/19)from washed recycled oil and control oil respectively.Conclusion:This washing procedure is safe and effective for the used treatment and for other sources of mineral oil used for embryo culture.     

First do no harm: The dangers of mineral oil

Chronic constipation is a very common problem in the paediatric population, and a particularly frequent issue in the management of neurologically impaired children. The use of mineral oil in the treatment of constipation has been well accepted because of its efficacy and infrequent side effects. The case of a three and a half-year-old girl with spastic quadriplegic cerebral palsy, who was admitted to hospital for investigation of increasing tachypnea and respiratory distress over a two-month period, is presented. This case highlights lipoid pneumonia due to mineral oil aspiration, which is a recognized severe complication of this medication, and emphasizes the need for a heightened awareness among caregivers about the potential dangers of inappropriate mineral oil use.     

Complex Segregation Analysis Accounting for GxE of Bone Mineral Density in European Pedigrees Selected Through a Male Proband with Low BMD

Osteoporosis is a common multifactorial disorder characterized by low bone mass (BMD) and high susceptibility to low-trauma fractures. Family and twin studies have found a strong genetic component in the determination of BMD, but the mode of inheritance of this trait is not yet fully understood. BMD is a complex trait whose expression is confounded by environmental influences and polygenic inheritance. Detection of potential gene-environment interactions is of great interest in the determination of bone health status. Here we have conducted segregation analyses, using the regressive class D models, in a sample of 100 European pedigrees (NEMO) with 713 subjects (524 measured for phenotypes) identified via a male with low BMD values at either the Lumbar Spine or the Femoral Neck. Segregation analyses were conducted on the residuals of LS-BMD and FN-BMD adjusted for gender, age and BMI. We tested for gene-covariate (GxE) interactions, and investigated the impact of significant GxE interactions on segregation results. Without GxE a major effect was found to be marginally significant in LS-BMD and highly significant in FN-BMD. For both traits the Mendelian hypothesis was rejected. Significant Age × gene and BMI × gene interactions were revealed. Accounting for GxE increased statistical evidence for a major factor in LS-BMD, and improved the fit of the data to the Mendelian transmission model for both traits. The best fitting models suggested a codominant major gene accounting for 45% (LS-BMD) and 44% (FN-BMD) of the adjusted BMDs. However, substantial residual correlations were also found, and these remained highly significant after accounting for the major gene.     

利用存在现象学定性研究患者满意度的体验元素

目的挖掘患者对医疗服务满意度的体验元素,提高对患者满意度的认识 。方法共访谈30 名近3年内在中国和芬兰均有就医经历的中国人。使用Atlas.ti软件对数据进行录入、处理和分析。资料分析主要采用主题分析法。结果访谈对象所反映出的体验模式基本一致。从访谈资料中发现,频度最高的4个体验要素包括“根治感”“安全感”“被关怀感”以及“合作感”。结论患者满意度是由不同的体验元素组成。要真正了解并提高患者对医疗服务的满意度,必须从患者角度深刻认识这些体验元素,深入探索组成元素的本体 、认知 、动态 和技术等层面,有针对性地改善服务模式和方式,最终提高患者对医疗服务的满意度。