全文获取类型
收费全文 | 70730篇 |
免费 | 4878篇 |
国内免费 | 895篇 |
专业分类
耳鼻咽喉 | 349篇 |
儿科学 | 985篇 |
妇产科学 | 1141篇 |
基础医学 | 2787篇 |
口腔科学 | 763篇 |
临床医学 | 11933篇 |
内科学 | 6359篇 |
皮肤病学 | 687篇 |
神经病学 | 1861篇 |
特种医学 | 964篇 |
外国民族医学 | 1篇 |
外科学 | 5589篇 |
综合类 | 10215篇 |
现状与发展 | 3篇 |
一般理论 | 3篇 |
预防医学 | 14581篇 |
眼科学 | 372篇 |
药学 | 13592篇 |
130篇 | |
中国医学 | 1227篇 |
肿瘤学 | 2961篇 |
出版年
2024年 | 87篇 |
2023年 | 1147篇 |
2022年 | 2111篇 |
2021年 | 3091篇 |
2020年 | 3372篇 |
2019年 | 2354篇 |
2018年 | 2272篇 |
2017年 | 2293篇 |
2016年 | 2409篇 |
2015年 | 2556篇 |
2014年 | 5955篇 |
2013年 | 6036篇 |
2012年 | 5245篇 |
2011年 | 5515篇 |
2010年 | 4322篇 |
2009年 | 3802篇 |
2008年 | 3825篇 |
2007年 | 3405篇 |
2006年 | 3022篇 |
2005年 | 2368篇 |
2004年 | 1948篇 |
2003年 | 1529篇 |
2002年 | 1106篇 |
2001年 | 910篇 |
2000年 | 787篇 |
1999年 | 713篇 |
1998年 | 545篇 |
1997年 | 461篇 |
1996年 | 370篇 |
1995年 | 319篇 |
1994年 | 309篇 |
1993年 | 252篇 |
1992年 | 210篇 |
1991年 | 170篇 |
1990年 | 137篇 |
1989年 | 118篇 |
1988年 | 132篇 |
1987年 | 121篇 |
1986年 | 120篇 |
1985年 | 149篇 |
1984年 | 147篇 |
1983年 | 90篇 |
1982年 | 86篇 |
1981年 | 69篇 |
1980年 | 77篇 |
1979年 | 52篇 |
1978年 | 63篇 |
1977年 | 55篇 |
1976年 | 61篇 |
1975年 | 65篇 |
排序方式: 共有10000条查询结果,搜索用时 156 毫秒
71.
通过探讨DRG支付方式改革下医院财务管理的应对策略,可以有效地降低医疗支付方式改革对医院财务管理的负面影响,促使医院财务管理在"危"与"机"的转换中抢抓机遇,促进医院财务管理提质增效。 相似文献
72.
《Journal of Pharmaceutical Analysis》2022,12(2):221-231
Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. It is a cancer that originates from the mammary ducts and involves mutations in multiple genes. Recently, the treatment of breast cancer has become increasingly challenging owing to the increase in tumor heterogeneity and aggressiveness, which gives rise to therapeutic resistance. Epidemiological, population-based, and hospital-based case-control studies have demonstrated an association between high intake of certain Allium vegetables and a reduced risk in the development of breast cancer. Diallyl disulfide (DADS) and diallyl trisulfide (DATS) are the main allyl sulfur compounds present in garlic, and are known to exhibit anticancer activity as they interfere with breast cancer cell proliferation, tumor metastasis, and angiogenesis. The present review highlights multidrug resistance mechanisms and their signaling pathways in breast cancer. This review discusses the potential anticancer activities of DADS and DATS, with emphasis on drug resistance in triple-negative breast cancer (TNBC). Understanding the anticancer activities of DADS and DATS provides insights into their potential in targeting drug resistance mechanisms of TNBC, especially in clinical studies. 相似文献
73.
74.
《Best Practice & Research: Clinical Rheumatology》2022,36(4):101810
Osteoarthritis (OA) is a highly prevalent joint disease that is associated with pain, loss of function, and high direct and indirect economic costs. The current therapeutic options are inadequate, providing only a moderate symptom relief without the possibility of disease modification. While treatment options and personalized medicines are increasing for many complex diseases, OA drug development has been impeded by the advanced state of disease at the time of diagnosis and intervention, heterogeneity in both symptoms and rates of progression, and a lack of validated biomarkers and relevant outcome measures. This review article summarizes the OA landscape, including therapies in development as potential OA treatments, potential biomarkers undergoing evaluation by the US Food and Drug Administration, and a summary of current OA treatment guidelines, with a particular focus on the knee OA. 相似文献
75.
《Journal of Pharmaceutical Analysis》2020,10(5):434-443
As a powerful tool to advance drug discovery, molecular imaging may provide new insights into the process of drug effect and therapy at cellular and molecular levels. When compared with other detection methods, fluorescence-based strategies are highly attractive and can be used to illuminate pathways of drugs’ transport, with multi-color capacity, high specificity and good sensitivity. The conjugates of fluorescent molecules and therapeutic agents create exciting avenues for real-time monitoring of drug delivery and distribution, both in vitro and in vivo. In this short review, we discuss recent developments of small molecule-based fluorophore-drug conjugates, including non-cleavable and cleavable ones, that are capable of visualizing drug delivery. 相似文献
76.
77.
《Gaceta sanitaria / S.E.S.P.A.S》2022,36(3):278-282
Continuous management improvement should be an aspiration for all public sector organizations. External comparison or benchmarking identifies good practices in similar organizations. For public health services, it is not easy to obtain such indicators. The objectives of this paper are to describe the process of conducting a benchmarking exercise for a public health agency, and to share its results. For this purpose, agencies that may be compared were identified, and their websites were searched for annual reports or other documents with indicators of the activities or results of public health services. Limitations and contextual aspects of the indicators of the different organizations were identified, as well as ways to improve their comparability. Finally, a set of 19 indicators is proposed, as an initial core for quality management comparisons. 相似文献
78.
79.
80.