全文获取类型
收费全文 | 44850篇 |
免费 | 2900篇 |
国内免费 | 922篇 |
专业分类
耳鼻咽喉 | 382篇 |
儿科学 | 953篇 |
妇产科学 | 336篇 |
基础医学 | 3283篇 |
口腔科学 | 398篇 |
临床医学 | 6112篇 |
内科学 | 8147篇 |
皮肤病学 | 185篇 |
神经病学 | 2545篇 |
特种医学 | 1194篇 |
外国民族医学 | 3篇 |
外科学 | 4861篇 |
综合类 | 6281篇 |
现状与发展 | 3篇 |
预防医学 | 2588篇 |
眼科学 | 5673篇 |
药学 | 4356篇 |
25篇 | |
中国医学 | 1191篇 |
肿瘤学 | 156篇 |
出版年
2024年 | 67篇 |
2023年 | 699篇 |
2022年 | 971篇 |
2021年 | 1855篇 |
2020年 | 1655篇 |
2019年 | 1446篇 |
2018年 | 1534篇 |
2017年 | 1388篇 |
2016年 | 1411篇 |
2015年 | 1336篇 |
2014年 | 2844篇 |
2013年 | 3270篇 |
2012年 | 2367篇 |
2011年 | 2643篇 |
2010年 | 2007篇 |
2009年 | 1962篇 |
2008年 | 2062篇 |
2007年 | 2106篇 |
2006年 | 1840篇 |
2005年 | 1572篇 |
2004年 | 1380篇 |
2003年 | 1085篇 |
2002年 | 975篇 |
2001年 | 1003篇 |
2000年 | 783篇 |
1999年 | 729篇 |
1998年 | 632篇 |
1997年 | 615篇 |
1996年 | 505篇 |
1995年 | 556篇 |
1994年 | 485篇 |
1993年 | 416篇 |
1992年 | 436篇 |
1991年 | 382篇 |
1990年 | 363篇 |
1989年 | 321篇 |
1988年 | 322篇 |
1987年 | 291篇 |
1986年 | 272篇 |
1985年 | 328篇 |
1984年 | 317篇 |
1983年 | 204篇 |
1982年 | 260篇 |
1981年 | 215篇 |
1980年 | 188篇 |
1979年 | 152篇 |
1978年 | 138篇 |
1977年 | 77篇 |
1976年 | 68篇 |
1975年 | 45篇 |
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
951.
952.
953.
954.
955.
Mitral valve resistance determines hemodynamic consequences of severe rheumatic mitral stenosis and immediate outcomes of percutaneous valvuloplasty 下载免费PDF全文
956.
957.
Weimin Tang Shaoxiong Zhuang Guoan Liu 《眼科学报》2014,(2):95-99
Purpose: To compare early visual function between patients undergoing phacoemulsification combined with multifocal and accommodative intraocular lens implantation.
Methods: A total of 112 patients with age-related cataract undergoing phacoemulsification in our hospital were recruited for this study and randomly assigned into multifocal (56 eyes; ZAM00 group) and accommodative (56 eyes; FLEX group) intraocular lens groups. Visual acuity and contrast sensitivity were statistically compared between the two groups.
Results: No significant difference was found in uncorrected distant visual acuity between the ZMA00 and FLEX groups at 1 week, or 1, 3, and 6 months after operation (all P〉0.05). At postoperative 6 months, no statistical significance was noted in distant and intermediate best-corrected visual acuity or in contrast sensitivity between the two groups (all P〉0.05). Patients in the ZMA00 group were superior to their counterparts in the FLEX group regarding near best corrected visual acuity, reading speed, and spectacle independence (all P〈0.05).
Conclusion: ZMA00 and FLEX IOL implantation can provide excellent distant and intermediate visual acuity for patients with age-related cataract. ZMA00 IOL is superior to FLEX in terms of near visual acuity. 相似文献
Methods: A total of 112 patients with age-related cataract undergoing phacoemulsification in our hospital were recruited for this study and randomly assigned into multifocal (56 eyes; ZAM00 group) and accommodative (56 eyes; FLEX group) intraocular lens groups. Visual acuity and contrast sensitivity were statistically compared between the two groups.
Results: No significant difference was found in uncorrected distant visual acuity between the ZMA00 and FLEX groups at 1 week, or 1, 3, and 6 months after operation (all P〉0.05). At postoperative 6 months, no statistical significance was noted in distant and intermediate best-corrected visual acuity or in contrast sensitivity between the two groups (all P〉0.05). Patients in the ZMA00 group were superior to their counterparts in the FLEX group regarding near best corrected visual acuity, reading speed, and spectacle independence (all P〈0.05).
Conclusion: ZMA00 and FLEX IOL implantation can provide excellent distant and intermediate visual acuity for patients with age-related cataract. ZMA00 IOL is superior to FLEX in terms of near visual acuity. 相似文献
958.
959.
Glaucomatous visual field progression has both personal and societal costs and therefore has a serious impact on quality of life. At the present time, intraocular pressure (IOP) is considered to be the most important modifiable risk factor for glaucoma onset and progression. Reduction of IOP has been repeatedly demonstrated to be an effective intervention across the spectrum of glaucoma, regardless of subtype or disease stage. In the setting of approval of IOP-lowering therapies, it is expected that effects on IOP will translate into benefits in long-term patient-reported outcomes. Nonetheless, the effect of these medications on IOP and their associated risks can be consistently and objectively measured. This helps to explain why regulatory approval of new therapies in glaucoma has historically used IOP as the outcome variable. Although all approved treatments for glaucoma involve IOP reduction, patients frequently continue to progress despite treatment. It would therefore be beneficial to develop treatments that preserve visual function through mechanisms other than lowering IOP. The United States Food and Drug Administration (FDA) has stated that they will accept a clinically meaningful definition of visual field progression using Glaucoma Change Probability criteria. Nonetheless, these criteria do not take into account the time (and hence, the speed) needed to reach significant change. In this paper we provide an analysis based on the existing literature to support the hypothesis that decreasing the rate of visual field progression by 30% in a trial lasting 12–18 months is clinically meaningful. We demonstrate that a 30% decrease in rate of visual field progression can be reliably projected to have a significant effect on health-related quality of life, as defined by validated instruments designed to measure that endpoint. 相似文献
960.
《Journal of dentistry》2013,41(7):636-641
ObjectivesThis study examined débridement efficacy as a result of wall shear stresses created by different irrigant delivery/agitation techniques in an inaccessible recess of a curved root canal model.MethodsA reusable, curved canal cavity containing a simulated canal fin was milled into mirrored titanium blocks. Calcium hydroxide (Ca(OH)2) paste was used as debris and loaded into the canal fin. The titanium blocks were bolted together to provide a fluid-tight seal. Sodium hypochlorite was delivered at a previously-determined flow rate of 1 mL/min that produced either negligible or no irrigant extrusion pressure into the periapex for all the techniques examined. Nine irrigation delivery/agitation techniques were examined: NaviTip passive irrigation control, Max-i-Probe® side-vented needle passive irrigation, manual dynamic agitation (MDA) using non-fitting and well-fitting gutta-percha points, EndoActivator™ sonic agitation with medium and large points, VPro™ EndoSafe™ irrigation system, VPro™ StreamClean™ continuous ultrasonic irrigation and EndoVac apical negative pressure irrigation. Débridement efficacies were analysed with Kruskal–Wallis ANOVA and Dunn's multiple comparisons tests (α = 0.05).ResultsEndoVac was the only technique that removed more than 99% calcium hydroxide debris from the canal fin at the predefined flow rate. This group was significantly different (p < 0.05) from the other groups that exhibited incomplete Ca(OH)2 removal.ConclusionsThe ability of the EndoVac system to significantly clean more debris from a mechanically inaccessible recess of the model curved root canal may be caused by robust bubble formation during irrigant delivery, creating higher wall shear stresses by a two-phase air–liquid flow phenomenon that is well known in other industrial débridement systems. 相似文献