全文获取类型
收费全文 | 55510篇 |
免费 | 4762篇 |
国内免费 | 1043篇 |
专业分类
耳鼻咽喉 | 252篇 |
儿科学 | 2395篇 |
妇产科学 | 837篇 |
基础医学 | 5822篇 |
口腔科学 | 1001篇 |
临床医学 | 7109篇 |
内科学 | 9314篇 |
皮肤病学 | 703篇 |
神经病学 | 818篇 |
特种医学 | 870篇 |
外国民族医学 | 3篇 |
外科学 | 5887篇 |
综合类 | 8270篇 |
现状与发展 | 7篇 |
预防医学 | 10835篇 |
眼科学 | 293篇 |
药学 | 4448篇 |
44篇 | |
中国医学 | 1127篇 |
肿瘤学 | 1280篇 |
出版年
2024年 | 159篇 |
2023年 | 965篇 |
2022年 | 1929篇 |
2021年 | 2523篇 |
2020年 | 2541篇 |
2019年 | 2065篇 |
2018年 | 1980篇 |
2017年 | 1956篇 |
2016年 | 2103篇 |
2015年 | 2254篇 |
2014年 | 3768篇 |
2013年 | 4233篇 |
2012年 | 3698篇 |
2011年 | 3900篇 |
2010年 | 2802篇 |
2009年 | 2643篇 |
2008年 | 2479篇 |
2007年 | 2565篇 |
2006年 | 2457篇 |
2005年 | 2160篇 |
2004年 | 1740篇 |
2003年 | 1519篇 |
2002年 | 1117篇 |
2001年 | 989篇 |
2000年 | 828篇 |
1999年 | 766篇 |
1998年 | 607篇 |
1997年 | 569篇 |
1996年 | 479篇 |
1995年 | 473篇 |
1994年 | 458篇 |
1993年 | 360篇 |
1992年 | 338篇 |
1991年 | 316篇 |
1990年 | 239篇 |
1989年 | 236篇 |
1988年 | 189篇 |
1987年 | 141篇 |
1986年 | 112篇 |
1985年 | 145篇 |
1984年 | 87篇 |
1983年 | 70篇 |
1982年 | 81篇 |
1981年 | 65篇 |
1980年 | 44篇 |
1979年 | 41篇 |
1978年 | 25篇 |
1977年 | 25篇 |
1976年 | 33篇 |
1975年 | 15篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
M. H. Wernitz S. Swidsinski K. Weist D. Sohr W. Witte K-P. Franke D. Roloff H. Rüden S. K. Veit 《Clinical microbiology and infection》2005,11(6):457-465
Screening of potential MRSA-positive patients at hospital admission is recommended in German and international guidelines. This policy has been shown to be effective in reducing the frequency of nosocomial MRSA transmissions in the event of an outbreak, but the influence of screening on reducing hospital-acquired MRSA infections in a hospital setting where MRSA is endemic is not yet well-documented. This study describes the effect of hospital-wide screening of defined risk groups in a 700-bed acute care hospital during a period of 19 months. In a cohort study with a 19-month control period, the frequencies of hospital-acquired MRSA infections were compared with and without screening. In the control period, there were 119 MRSA-positive patients, of whom 48 had a hospital-acquired MRSA infection. On the basis of this frequency, a predicted total of 73.2 hospital-acquired MRSA infections was calculated for the screening period, but only 52% of the expected number (38 hospital-acquired MRSA infections) were observed, i.e., 48% of the predicted number of hospital-acquired MRSA infections were prevented by the screening programme. The screening programme was performed with minimal effort and can therefore be recommended as an effective measure to help prevent hospital-acquired MRSA infections. 相似文献
22.
23.
献血者HBsAg多位点变异1例 总被引:2,自引:0,他引:2
我国是HBV的高流行区,HBsAg流行率在10%左右。因此在采供血中HBV的筛查显得尤为重要。目前所用的ELISA方法检测HBsAg有着很高的灵敏度和特异性.有效防止了HBV的经血传播。然而HBV在复制过程中涉及逆转录,大大增高了碱基错配的频度,为HBV迅速变异提供了分子基础。随着HBV疫苗接种的不断推广和高效价免疫球蛋白以及抗病毒药物的应用,一方面有效切断和抑制了HBV的感染、传播和复制,另一方面也导致变异株的出现。我们从献血者中发现了1例HBsAg发生变异的个体,并分析其基因序列,研究其对检测的影响,现报告如下。 相似文献
24.
肾移植术后肺部真菌感染的诊治 总被引:8,自引:0,他引:8
目的 探讨肾移植术后肺部真菌感染的诊断与治疗。 方法 回顾性分析 4 3例肾移植术后肺部真菌感染患者的临床资料。男 35例 ,女 8例 ,平均年龄 32岁。发病时间平均为术后 5 9d。 结果 4 3例患者中 ,白色念珠菌 16例 ,克柔念珠菌 4例 ,近平滑念珠菌 2例 ,曲霉菌 4例 ,毛霉菌 3例 ,新型隐球菌 1例 ,奴卡菌 2例 ,其中 14例有细菌、巨细胞病毒混合感染。 11例培养阴性。氟康唑10 0mg/次 ,3次 /d ,连续 10d ,治愈 2 3例 ;两性霉素B脂质体 5 0mg/d ,连续 10d ,治愈 17例 ;死亡 3例。 结论 肺部真菌感染是肾移植术后的严重并发症 ,死亡率高。早期诊断与治疗效果良好。 相似文献
25.
The purpose of this study is to show the spectrum of adjacent organ invasion and to make a brief review of hepatic alveolar hydatid disease (AHD), using CT and MR imaging. We retrospectively reviewed CT and MR images of three patients with various adjacent organ invasions surgically and histologically proven to be AHD. Local invasion to right kidney and adrenal, right hemidiaphragm and lung were detected in one patient, right adrenal in another patient and gall bladder, duodenum, gastric wall and pancreas invasion in the other. AHD may rarely extend to the gall bladder, stomach, duodenum, pancreas, right adrenal and kidney, diaphragm, pleura and lung. The extension of the disease outside the liver is usually encountered in patients with large, peripherally located masses in the advanced stage of the disease. 相似文献
26.
金桂红 《安徽卫生职业技术学院学报》2005,4(6):35-36
目的:探讨小儿腮腺炎并发中枢神经系统感染的临床特点.方法:对52例小儿腮腺炎并发中枢神经系统感染的临床资料进行回顾性总结分析.结果:3~7月份为小儿腮腺炎并发中枢神经系统感染的发病高峰季节(92.31%).发病年龄以6~12岁为主(82.69%),多发生于腮腺肿痛3天以上伴有持续发热者(78.85%),少数患者同时有其它脏器的损害,一般治疗疗效较好.结论:腮腺炎极易并发中枢神经系统感染,年长儿发生率高,应推广接种流腮活疫苗降低发病率. 相似文献
27.
28.
Intracranial actinomycosis in juvenile patients
Case report and review of the literature 总被引:1,自引:0,他引:1
F. Puzzilli Maurizio Salvati Andrea Ruggeri Antonino Raco Roberto Bristot Stefano Bastianello Pierpaolo Lunardi 《Child's nervous system》1998,14(9):463-466
A case of actinomycotic brain infection in a juvenile patient is described. Cases of actinomycosis affecting the head and
neck are rare, particularly in juvenile patients. In this case complete resolution of the infection was achieved by means
of surgical treatment and prolonged antibiotic therapy. The authors emphasize the importance of a combined approach for treatment
of this unusual brain infection and stress the difficulties involved in the diagnosis of this pathology.
Received: 3 November 1997 相似文献
29.
Wendy E. Marshman MD FRACO Christopher J. Lyons FRCS 《Clinical & experimental ophthalmology》1998,26(2):161-163
Purpose: To highlight an unusual organism causing a unilateral endophthalmitis by transplacental spread.
Method: We report a case of Plesiomonas shigelloides endophthalmitis, presenting in a newborn, with co-existing septicaemia and meningitis. There was a significant maternal history of diarrhoea associated with the ingestion of oysters 2 weeks prior to delivery.
Result: The endophthalmitis was treated with parenteral antibiotics and topical mydriatics with complete resolution, although subsequent assessment of the affected eye suggests a poor visual outcome.
Conclusion: Endophthalmitis in the newborn is an unusual clinical finding and usually presents with other manifestations of bacteraemia. Plesiomonas shigelloides is fortunately an infrequent cause of neonatal infection, but is associated with a high degree of morbidity and mortality. We postulate that this neonate acquired P. shigelloides via the transplacental route, and suggest that this organism be included in the list of 'other' causes of transplacental infection that has been abbreviated to 'O' in the acronym TORCH. 相似文献
Method: We report a case of Plesiomonas shigelloides endophthalmitis, presenting in a newborn, with co-existing septicaemia and meningitis. There was a significant maternal history of diarrhoea associated with the ingestion of oysters 2 weeks prior to delivery.
Result: The endophthalmitis was treated with parenteral antibiotics and topical mydriatics with complete resolution, although subsequent assessment of the affected eye suggests a poor visual outcome.
Conclusion: Endophthalmitis in the newborn is an unusual clinical finding and usually presents with other manifestations of bacteraemia. Plesiomonas shigelloides is fortunately an infrequent cause of neonatal infection, but is associated with a high degree of morbidity and mortality. We postulate that this neonate acquired P. shigelloides via the transplacental route, and suggest that this organism be included in the list of 'other' causes of transplacental infection that has been abbreviated to 'O' in the acronym TORCH. 相似文献
30.
王慧伶 《南京军医学院学报》1998,(2)
呼吸道感染是呼吸系统常见病、多发病。利用杭州地区1990年1月~1992年12月气象资料作了统计分析,并对同期来海军杭州疗养院门诊就诊的呼吸道感染病人进行了调查。结果为1~3、11、12月发病率高,与5~9月相比有非常显著差异(P<0.001),呼吸道感染与气温低,湿度高,温差大,天气骤变等气象因素密切相关。潮冷天气(气温在10℃以下),频繁降温(每月3次以上),大幅度降温(4℃以上)三种气象因素共同存在情况下可导致呼吸道感染性疾病的高发。同时从气象学角度提出了预防该病的一些措施。 相似文献