全文获取类型
收费全文 | 22088篇 |
免费 | 2591篇 |
国内免费 | 296篇 |
专业分类
耳鼻咽喉 | 173篇 |
儿科学 | 853篇 |
妇产科学 | 192篇 |
基础医学 | 2197篇 |
口腔科学 | 1699篇 |
临床医学 | 1655篇 |
内科学 | 4698篇 |
皮肤病学 | 647篇 |
神经病学 | 1954篇 |
特种医学 | 305篇 |
外国民族医学 | 3篇 |
外科学 | 1538篇 |
综合类 | 1444篇 |
现状与发展 | 6篇 |
预防医学 | 4045篇 |
眼科学 | 538篇 |
药学 | 701篇 |
4篇 | |
中国医学 | 131篇 |
肿瘤学 | 2192篇 |
出版年
2024年 | 25篇 |
2023年 | 377篇 |
2022年 | 295篇 |
2021年 | 951篇 |
2020年 | 964篇 |
2019年 | 1003篇 |
2018年 | 1051篇 |
2017年 | 944篇 |
2016年 | 924篇 |
2015年 | 940篇 |
2014年 | 1325篇 |
2013年 | 1796篇 |
2012年 | 1027篇 |
2011年 | 1295篇 |
2010年 | 985篇 |
2009年 | 1038篇 |
2008年 | 1049篇 |
2007年 | 986篇 |
2006年 | 912篇 |
2005年 | 754篇 |
2004年 | 743篇 |
2003年 | 688篇 |
2002年 | 646篇 |
2001年 | 515篇 |
2000年 | 335篇 |
1999年 | 302篇 |
1998年 | 308篇 |
1997年 | 357篇 |
1996年 | 288篇 |
1995年 | 252篇 |
1994年 | 216篇 |
1993年 | 180篇 |
1992年 | 197篇 |
1991年 | 188篇 |
1990年 | 156篇 |
1989年 | 148篇 |
1988年 | 120篇 |
1987年 | 103篇 |
1986年 | 109篇 |
1985年 | 83篇 |
1984年 | 61篇 |
1983年 | 65篇 |
1982年 | 53篇 |
1981年 | 47篇 |
1980年 | 47篇 |
1979年 | 27篇 |
1978年 | 20篇 |
1977年 | 24篇 |
1976年 | 17篇 |
1974年 | 15篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
991.
Javier Caballero‐Gmez Ignacio García Bocanegra Flix Gmez‐Guillamn Leonor Camacho‐Sillero Irene Zorrilla Pedro Lopez‐Lopez David Cano‐Terriza Saúl Jimnez‐Ruiz Mario Frias Antonio Rivero‐Juarez 《Transboundary and Emerging Diseases》2020,67(4):1422-1427
In recent decades, cases of autochthonous hepatitis E (HE) have sharply increased in European countries where foodborne transmission is considered the main route of HE virus (HEV) transmission. Although rabbits are considered the main reservoir of the zoonotic HEV‐3ra subtype, information on the role of wild lagomorphs in the epidemiology of HEV remains scarce. The aim of this study therefore was to assess the circulation of HEV in European wild rabbits (Oryctolagus cuniculus) and Iberian hares (Lepus granatensis), the most important lagomorph species in Spanish Mediterranean ecosystems. Liver samples from 372 wild rabbits and 78 Iberian hares were analysed using a broad‐spectrum RT‐PCR that detects HEV genotypes 1–8. None of the 450 lagomorphs tested were positive for HEV infection. To the best of our knowledge, this is the first study to assess HEV circulation in wild rabbits in Spain and the first to evaluate HEV infection in Iberian hares. Our results indicate absence of HEV circulation in wild rabbits and Iberian hares in southern Spain during the study period, which suggests that the risk of transmission of HEV from wild lagomorphs to other species, including humans, is low. 相似文献
992.
Chang‐Zhan Xie Zhuo Ha Han Zhang Ying Zhang Yu‐Biao Xie He Zhang Fu‐Long Nan Zheng Wang Ping Zhang Wang Xu Ji‐Cheng Han Shu‐Bo Wen Hui‐Jun Lu Ning‐Yi Jin 《Transboundary and Emerging Diseases》2020,67(5):2065-2072
Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that causes reproductive failure in sows and respiratory problems in piglets. PRRSV infection leads to substantial pig mortality and causing huge economic losses so that disease outbreaks caused by the new PRRSV strain from other regions have caused great concern in China. In this study, we analysed the pathogenicity of the novel ORF5 RFLP 1‐7‐4‐like PRRSV strain, named PRRSV‐ZDXYL‐China‐2018‐1 in pigs. The viral challenge test showed that PRRSV‐ZDXYL‐China‐2018‐1 infection can cause persistent fever, moderate dyspnoea, serum viraemia and interstitial pneumonia in piglets. The levels of viral loads in serum and PRRSV‐specific antigen were also detected in lung tissues were used one‐step Taq‐Man RT‐qPCR and Immunohistochemistry, respectively. At 28dpi, the level of specific antibodies was increased among infected piglets. Importantly, the new virus appeared be a moderately virulent isolate with pathogenicity compared to HP‐PRRSV strain LQ (JXA1‐like strain). Histological examination revealed severe monocyte haemorrhage and interstitial pneumonia associated with monocyte infiltration in the lung tissue of pigs infected with PRRSV‐ZDXYL‐China‐2018‐1 and LQ‐JXA1 strains. Immunohistochemistry (IHC) results showed positive brown‐red epithelial cells and macrophages in pig lungs. Therefore, it is critical to establish an effective strategy to control the spread of PRRSV in China. 相似文献
993.
Jesse D. Schold Joshua J. Augustine Anne M. Huml John OToole John R. Sedor Emilio D. Poggio 《American journal of transplantation》2020,20(3):769-778
Success of transplantation is not limited to initial receipt of a donor organ. Many kidney transplant recipients experience graft loss following initial transplantation and the benefits of expedited placement on the waiting list and retransplantation extend to this population. Factors associated with access to repeat transplantation may be unique given experience with the transplant process and prior viability as a candidate. We examined the incidence, risk factors, secular changes, and center‐level variation of preemptive relisting or transplantation (PRLT) for kidney transplant recipients in the United States with graft failure (not due to death) using Scientific Registry of Transplant Recipients data from 2007 to 2018 (n = 39 557). Overall incidence of PRLT was 15% and rates of relisting declined over time. Significantly lower PRLT was evident among patients who were African American and Hispanic, males, older, obese, publicly insured, had lower educational attainment, were diabetic, had longer dialysis time prior to initial transplant, shorter graft survival, longer distance to transplant center, and resided in distressed communities. There was significant variation in PRLT by center, median = 13%, 10th percentile = 6%, 90th percentile = 24%. Cumulatively, results indicate that despite prior access to transplantation, incidence of PRLT is modest with pronounced clinical, social, and center‐level sources of variation suggesting opportunities to improve preemptive care among patients with failing grafts. 相似文献
994.
Sonya S. Brady PhD Amanda Berry PhD CRNP Deepa R. Camenga MD MHS Colleen M. Fitzgerald MD MS Sheila Gahagan MD MPH Cecilia T. Hardacker MSN RN CNL Bernard L. Harlow PhD Jeni Hebert-Beirne PhD MPH D. Yvette LaCoursiere MD Jessica B. Lewis PhD MFT Lisa K. Low PhD CNM Jerry L. Lowder MD MSc Alayne D. Markland DO MSc Gerald McGwin PhD Diane K. Newman DNP ANP-BC FAAN Mary H. Palmer PhD David A. Shoham PhD Ariana L. Smith MD Ann Stapleton MD Beverly R. Williams PhD Siobhan Sutcliffe PhD Prevention of Lower Urinary Tract Symptoms 《Neurourology and urodynamics》2020,39(4):1185-1202
995.
996.
Chris Grant Taylor Tuff Melissa Corso James J. Young Paula J. Stern Elie Ct Pierre Ct 《The Journal of the Canadian Chiropractic Association》2020,64(3):165
ObjectiveTo determine the incidence and risk factors of musculoskeletal disorders of the elbow in baseball pitchers.DesignSystematic review.Data SourcesMedline, CINAHL, Cochrane, PubMed and SportDiscus from onset to July 7, 2018.Eligibility CriteriaEligible studies included randomized controlled trials, cohort studies and case-control studies. Independent pairs of reviewers screened titles and abstracts for eligibility. Relevant articles were critically appraised for internal validity using the SIGN criteria. We included low risk of bias studies in our best evidence synthesis.ResultsWe retrieved 4502 articles, 39 were critically appraised and nine had a low risk of bias. These were included in the evidence synthesis. The incidence of musculoskeletal disorders of the elbow ranges from 2.3% in adolescent pitchers to 40.6% in youth pitchers. Evidence suggests that pitch characteristics, inadequate rest, biomechanical and anthropometric factors may be risk factors of UCL tears.Summary/ConclusionBaseball pitchers develop musculoskeletal disorders of the elbow. There is little high-quality evidence to understand the etiology. Preliminary evidence suggests the risk factors are multifactorial.PROSPERO Trial Registration Number: CRD42018092081 相似文献
997.
998.
Rahim Lalji Hayden Snider Noah Chow Scott Howitt 《The Journal of the Canadian Chiropractic Association》2020,64(3):187
BackgroundIn 2015, the U.S. Soccer Federation banned heading for players aged 10–13.Purpose/QuestionTo assess the change in proportion of children aged 10–13 playing soccer in the US presenting to an Emergency Department (ED) with a concussion in relation to any other injury before and after the ban.MethodsAnalysis was restricted to soccer athletes between 10–13 years that reported to a National Electronic Injury Surveillance System (NEISS) participating hospital ED following injury in 2013–2014 and 2016–2017. Multivariable logistic regression was performed to assess the association between year of injury and concussion diagnosis in relation to other injury diagnosis after adjusting for age, sex, and ethnicity.ResultsConcussion in relation to other injuries showed a significant increase in 2016–2017 when compared to 2013–2014 after adjustment (OR= 1.286, 95%CI = 1.090–1.517).ConclusionsThese results suggest that banning heading may not reduce concussion within this population. However, significant confounders, including increased reporting, were not controlled for. 相似文献
999.
Brian J. Boyarsky Jessica M. Ruck Teresa Po-Yu Chiang William A. Werbel Alexandra T. Strauss Samantha N. Getsin Kyle R. Jackson Amber B. Kernodle Sarah E. Van Pilsum Rasmussen Talia B. Baker Fawaz Al Ammary Christine M. Durand Robin K. Avery Allan B. Massie Dorry L. Segev Jacqueline M. Garonzik-Wang 《Clinical transplantation》2020,34(12):e14086
In our first survey of transplant centers in March 2020, >75% of kidney and liver programs were either suspended or operating under restrictions. To safely resume transplantation, we must understand the evolving impact of COVID-19 on transplant recipients and center-level practices. We therefore conducted a six-week follow-up survey May 7-15, 2020, and linked responses to the COVID-19 incidence map, with a response rate of 84%. Suspension of live donor transplantation decreased from 72% in March to 30% in May for kidneys and from 68% to 52% for livers. Restrictions/suspension of deceased donor transplantation decreased from 84% to 58% for kidneys and from 73% to 42% for livers. Resuming transplantation at normal capacity was envisioned by 83% of programs by August 2020. Exclusively using local recovery teams for deceased donor procurement was reported by 28%. Respondents reported caring for a total of 1166 COVID-19–positive transplant recipients; 25% were critically ill. Telemedicine challenges were reported by 81%. There was a lack of consensus regarding management of potential living donors or candidates with SARS-CoV-2. Our findings demonstrate persistent heterogeneity in center-level response to COVID-19 even as transplant activity resumes, making ongoing national data collection and real-time analysis critical to inform best practices. 相似文献
1000.
《Journal of Clinical Orthopaedics and Trauma》2020,11(6):1158-1161
IntroductionAcetabular fractures in the elderly population are particularly challenging for orthopedic fracture surgeons to treat. Anterior column posterior hemitransverse (ACH) and both column (BC) fractures account for over 70% of these injuries in geriatric patients. Nonoperative management of these injuries has a mortality of about 79% and patients generally have a minimal chance of return to independent living. The aim of our study was to identify the degree of protrusio deformity geriatric patients with these injuries present with and if indirect reduction through a Stoppa approach was sufficient to improve protrusio deformity.MethodsPatients older than 60 years of age who had ACH and BC pattern acetabular fractures treated at the BIDMC in Boston, MA between 2015 and 2020 were included in this study. Pelvic AP and Judet views were reviewed at injury and each available post-operative follow up. We modified the femoral head extrusion index and used its inverse to measure the level of protrusio at each time point (-FHEI). Patient outcomes were also graded as excellent, good, fair and poor based on post-operative follow up.ResultsSixteen patients were included based on above criteria and average -FHEI at injury was 34.85% and decreased significantly to an average of 21.5% postoperatively and remained stable at all follow up points. At one year follow up (n = 2), the mean -FHEI was 18.15%. Most patients had good (4) or excellent (9) outcomes.ConclusionsWe present short term results of indirect reduction of ACH and BC acetabular fractures in geriatric patients using a PRO quadrilateral surface plate, which was largely successful in controlling the primary protrusio deformity seen in these patients. This allowed for restoration of the anterior column, with limited surgical morbidity through a relatively simple and straightforward surgical approach. 相似文献