全文获取类型
收费全文 | 9422篇 |
免费 | 376篇 |
国内免费 | 46篇 |
专业分类
耳鼻咽喉 | 42篇 |
儿科学 | 231篇 |
妇产科学 | 177篇 |
基础医学 | 567篇 |
口腔科学 | 183篇 |
临床医学 | 832篇 |
内科学 | 1197篇 |
皮肤病学 | 83篇 |
神经病学 | 496篇 |
特种医学 | 184篇 |
外科学 | 1702篇 |
综合类 | 1881篇 |
预防医学 | 1306篇 |
眼科学 | 37篇 |
药学 | 655篇 |
7篇 | |
中国医学 | 133篇 |
肿瘤学 | 131篇 |
出版年
2024年 | 19篇 |
2023年 | 149篇 |
2022年 | 243篇 |
2021年 | 389篇 |
2020年 | 303篇 |
2019年 | 740篇 |
2018年 | 616篇 |
2017年 | 368篇 |
2016年 | 224篇 |
2015年 | 224篇 |
2014年 | 569篇 |
2013年 | 570篇 |
2012年 | 513篇 |
2011年 | 483篇 |
2010年 | 404篇 |
2009年 | 348篇 |
2008年 | 310篇 |
2007年 | 267篇 |
2006年 | 262篇 |
2005年 | 228篇 |
2004年 | 162篇 |
2003年 | 129篇 |
2002年 | 105篇 |
2001年 | 87篇 |
2000年 | 76篇 |
1999年 | 62篇 |
1998年 | 47篇 |
1997年 | 36篇 |
1996年 | 30篇 |
1995年 | 28篇 |
1994年 | 44篇 |
1993年 | 28篇 |
1992年 | 17篇 |
1990年 | 14篇 |
1989年 | 12篇 |
1988年 | 15篇 |
1986年 | 17篇 |
1985年 | 123篇 |
1984年 | 207篇 |
1983年 | 132篇 |
1982年 | 149篇 |
1981年 | 140篇 |
1980年 | 131篇 |
1979年 | 133篇 |
1978年 | 112篇 |
1977年 | 92篇 |
1976年 | 136篇 |
1975年 | 109篇 |
1974年 | 101篇 |
1973年 | 117篇 |
排序方式: 共有9844条查询结果,搜索用时 15 毫秒
101.
性病防治所和综合医院皮肤性病科性病患者求医行为研究 总被引:4,自引:0,他引:4
目的 比较性病患者选择性病防治所和综合医院皮肤性病科求医行为差别,探讨患者采取不同求医行为因素和丰富求医行为研究内容。方法 按事先拟定的结构式问卷,在知情同意前提下,对北京390例性防所性病患者、55例综合医院性病患者进行个人访谈。结果 性病知识得分越高、首诊知道设有性病防治所者,倾向于选择性防所,就近就医倾向于选择综合医院皮肤性病科。结论 性病防治所、综合医院皮肤性病科在性病高危人群及一般人群中的知晓度是影响患者就诊不可忽视的因素,性病防治所由于它们在治疗和控制性病中的特殊地位,是确定卫生资源的重要条件之一。 相似文献
102.
BACKGROUND: We studied the sevoflurane-sparing effect of nitrous oxide in a prospective randomised study. METHODS: Forty-two ASA I-II patients scheduled for elective knee arthroscopy under general anaesthesia were randomly assigned to a fresh gas flow consisting of oxygen in air or oxygen in nitrous oxide 1:2. All patients received a standardised anaesthesia consisting of induction with fentanyl and propofol and maintenance with sevoflurane adjusted according to clinical signs. The sevoflurane consumption was studied by means of weighing the vaporiser before and after every anaesthesia. RESULTS: The mean sevoflurane consumption was reduced from 0.62 to 0.25 g/min, a 60% reduction, by the use of oxygen in nitrous oxide 1:2 in the fresh gas flow. The emergence was faster for the patients receiving nitrous oxide. No major differences were observed during recovery. CONCLUSION: Nitrous oxide was found to be cost-effective for use during short ambulatory knee arthroscopy. 相似文献
103.
104.
针对居民的医疗保健要求探索全科医疗的开展 总被引:1,自引:0,他引:1
通过对宜川街道赵园二委1700余户居民进行家庭健康问卷调查,结果大约有30%居民愿意接受全科医疗服务模式,40%居民需要上门服务,当遇到常见病时首选一级医院医生为对象占50%,70%居民认为上门服务应该是有偿的。为此,笔者认为基层医院应在社区卫生服务中大力地探索,只要有市场就应去占领,而且是一级医院赖以生存的社区,应以全科医疗服务模式去改变医患之间关系,把预防保健、医疗、康复、健康教育融为一体,使 相似文献
105.
试析大型综合医院在社区医疗服务中的作用 总被引:7,自引:1,他引:6
根据国家城市卫生服务体系改革的原则及对基层医院和大医院的功能定位,分析大型综合医院在社区医疗服务中的作用。指出大型综合医院应加强与城市基层医院的联系,建立全科医生培训基地,为社区医疗服务输送适用人才,建立切实可行的转诊制度,成为社区医疗服务的坚强后盾,提高社区医疗服务的质量和水平,促进社区医疗服务的发展。 相似文献
106.
Arthurs BP Khalil MK Chagnon F Lindley SK Anderson DP Burnier M 《Ophthalmology》1999,106(12):2387-2390
OBJECTIVE: To present a patient with systemic lupus erythematosus who developed infarction and melting of the orbit secondary to her systemic disease. DESIGN: A case report. PARTICIPANT: A 61-year-old white woman with a 5-year history of systemic lupus erythematosus. METHODS: The patient presented with left orbital pain, limitation of extraocular movements, and a fistula from the ethmoid sinus to the upper eyelid. A detailed examination with computerized tomography, ultrasound, and a comprehensive medical evaluation with laboratory testing was performed. Histopathologic analysis with special stains of the orbital tissues was also performed. RESULTS: Histopathologic examination of the biopsy specimens revealed the features of an inflammatory process involving the orbit, similar to a panniculitis. These include a lymphocytic reaction with a predominance of plasma cells, vasculitis with occlusion, and thickening of the vessel walls, necrosis, and hyalinization of fat. CONCLUSION: This is a unique case in which infarction and melting of the entire orbital structures occurred in the presence of systemic lupus erythematosus. The underlying disease process is a lupus-related panniculitis. The authors stress that this is a very rare entity and that other diseases should be ruled out before entertaining this diagnosis. 相似文献
107.
Maberley DA Yannuzzi LA Gitter K Singerman L Chew E Freund KB Noguiera F Sallas D Willson R Tillocco K 《Ophthalmology》1999,106(12):2248-52; discussion 2252-3
Objective
To examine the association between previous radiation exposure and idiopathic perifoveal telangiectasis (IPT).Design
A multicentered, individually matched, case-control study design was used.Participants/controls
Sixty-five case subjects were matched with 175 control subjects. Individuals with unequivocal evidence of angiographically confirmed IPT were included as cases. Control subjects were matched for center, age, and gender.Main outcome measure
The main exposures of interest were a history of therapeutic head or neck irradiation and environmental radiation exposure.Methods
A standardized questionnaire was administered to case and control subjects. Data were collected for the main exposures of interest as well as pertinent covariates. Conditional logistic regression was used to evaluate therapeutic and environmental radiation as risks for IPT.Results
On univariate analysis, head or neck irradiation was associated with IPT (odds ratios [OR] = 4.15, 95% confidence interval [CI] = 1.30–13.24). While controlling for diabetes and family history of diabetes, IPT was found to be associated with both head or neck irradiation (OR = 4.06, 95% CI = 1.20–13.76) and with environmental irradiation (OR = 6.73, 95% CI = 1.06–42.74).Conclusions
This study presents a previously unreported association between prior radiation exposure and IPT. 相似文献108.
Miró O Barrientos A Alonso JR Casademont J Jarreta D Urbano-Márquez A Cardellach F 《European journal of clinical pharmacology》1999,55(1):35-41
Background: General anaesthetics inhibit mitochondrial function in animal models. However, very few studies have been performed in humans,
and the results have not been conclusive.
Methods: We prospectively studied the oxygen consumption and the individual enzyme activity of each complex of the mitochondrial
respiratory chain of skeletal muscle mitochondria in 54 healthy individuals who underwent general anaesthesia for orthopaedic
surgery. The control group (n = 54) was made up of individuals submitted to the same orthopaedic procedure under regional anaesthesia (n = 31), and patients who underwent muscle biopsies for diagnostic purposes by local anaesthesia (n = 23).
Results: We found a significant decrease in the oxidation of glutamate (−36%), succinate (−25%) and ascorbate (−29%) in the general
anaesthetic group compared with the controls (P < 0.001 for all substrates). The level of such inhibition was similar for volatile anaesthetics with strong (halothane) or
weak (isoflurane) negative inotropic effect. By contrast, the enzymatic activity of all individual complexes and the coupling
of oxidative phosphorylation did not differ between the two groups.
Conclusion: We conclude that during general anaesthetic procedures there is an extensive inhibition of substrate oxidation in human
muscle mitochondria, and that it is not caused by a direct effect on complexes of the mitochondrial respiratory chain or through
uncoupling oxidative phosphorylation.
Received: 27 July 1998 / Accepted in revised form: 27 October 1998 相似文献
109.
110.