Pathological gambling in two patients on dopamine replacement therapy for Parkinson’s disease

Abstract. We describe two cases where increases in dopaminergic therapy were initiated by the patients due to perceived deterioration in symptoms of idiopathic Parkinsons disease. Shortly afterwards, both cases also met clinical criteria for pathological gambling. To date, only 29 cases of pathological gambling in patients with Parkinsons disease have been reported. This pathological gambling disorder is an addiction-like behavior triggered by excessive dopaminergic drugs and does not respond to standard therapy for pathological gambling. It only responds to an adjustment of Parkinsons disease therapy.     

利用转基因植物制备S-IgA的研究进展

S—IgA作为口腔防御系统的第一道屏障，在龋病防治方面具有重要作用。利用转基因植物生产抗体可较好地解决S—IgA大规模的生产和应用问题。本文就转基因植物表达系统的特点，抗体生产中所涉及的问题及S—IgA的最新研究进展作一综述。