医药行业域名争议与仲裁

互联网的发展使得域名的重要性和有限性日益彰显,从而不可避免的使域名成为企业抢注和争夺的对象。本文介绍了域名争议的仲裁机构以及医药行业在域名争议时,如何采用仲裁的办法来解决争端,以保护企业合法的权益。     

国产硝苯地平控释片治疗高血压并左室肥厚的临床研究

目的：评价国产控释剂型的硝苯地平（欣然）治疗高血压并左心室肥厚的临床疗效。方法：60例高血压病并左室肥厚患患者随机分为两组，欣然组（国产硝苯地平控释片）和拜新同（德国产硝苯地平控释片）组各30例，30mg／d口服，治疗3个月，观察降压疗效和左室肥厚的变化，结果：（1）欣然组降总有效率90％，拜新同组总有效率96．6％，两组疗效比较差异无显著性，P＞0．05。（2）两组治疗后左室内径，舒张期室间隔厚度和左室壁厚度均缩小，左室重量减少，左室射血分数提高，与治疗前比较均有显著性差异（P＜0．05），两组各项指标变化差值比较无显著差异（P＞0．05），结论：欣然能有效治疗高血压，并能逆转左心室肥厚。     

再议我国医用矿泉的分类命名及表示法

再议我国医用矿泉的分类命名及表示法张恒久王占东目的为充分发挥我国医用矿泉的医疗保健作用，尽快统一医用矿泉的分类、命名和表示方法，提出本人修订意见，与同道探讨。方法查阅国内、国外矿泉医学资料，结合作者实践。结果１医学矿泉定义：凡自然涌出或动力开采、含...     

The modulatory effect of semantic familiarity on the audiovisual integration of face‐name pairs

To recognize individuals, the brain often integrates audiovisual information from familiar or unfamiliar faces, voices, and auditory names. To date, the effects of the semantic familiarity of stimuli on audiovisual integration remain unknown. In this functional magnetic resonance imaging (fMRI) study, we used familiar/unfamiliar facial images, auditory names, and audiovisual face‐name pairs as stimuli to determine the influence of semantic familiarity on audiovisual integration. First, we performed a general linear model analysis using fMRI data and found that audiovisual integration occurred for familiar congruent and unfamiliar face‐name pairs but not for familiar incongruent pairs. Second, we decoded the familiarity categories of the stimuli (familiar vs. unfamiliar) from the fMRI data and calculated the reproducibility indices of the brain patterns that corresponded to familiar and unfamiliar stimuli. The decoding accuracy rate was significantly higher for familiar congruent versus unfamiliar face‐name pairs (83.2%) than for familiar versus unfamiliar faces (63.9%) and for familiar versus unfamiliar names (60.4%). This increase in decoding accuracy was not observed for familiar incongruent versus unfamiliar pairs. Furthermore, compared with the brain patterns associated with facial images or auditory names, the reproducibility index was significantly improved for the brain patterns of familiar congruent face‐name pairs but not those of familiar incongruent or unfamiliar pairs. Our results indicate the modulatory effect that semantic familiarity has on audiovisual integration. Specifically, neural representations were enhanced for familiar congruent face‐name pairs compared with visual‐only faces and auditory‐only names, whereas this enhancement effect was not observed for familiar incongruent or unfamiliar pairs. Hum Brain Mapp 37:4333–4348, 2016. © 2016 Wiley Periodicals, Inc.     

传染病医院CA电子签名系统的技术与实施

为推进医院无纸化进程,保证电子病历的法律效力、减少院内感染,本文论述了传染病医院电子签名基本概念与相关技术原理,通过部署数字证书管理、数字签名验证、电子签章和时间戳系统,将电子签名服务与医院各个系统进行安全集成,实现可靠的电子签名。建立医院统一的电子认证服务体系和业务应用安全支撑体系,保证电子病历的真实性、合法性,减少各业务环节医护人员易受感染的环节,对加强医疗管理、提高医疗效率具有重要意义。     

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein

OBJECTIVE: In the present study, we investigated the effects of rosiglitazone (10 mg/kg, i.p.), a PPAR-gamma agonist, on the development of acute pancreatitis. DESIGN: Intraperitoneal injection of cerulein in mice induced an acute pancreatitis characterized by edema, neutrophil infiltration elevated serum levels of amylase and lipase. This experimental model was performed to test the anti-inflammatory activity of rosiglitazone. SETTING. University research laboratory. INTERVENTIONS: Male CD mice (20-22 g) were allocated into four groups (n=10 for each group): (a) Cerulein+vehicle group. Mice were treated hourly (x 5) with cerulein (50 microg/kg, in saline solution, i.p.); (b) Rosiglitazone group (same as the Cerulein+vehicle group but were administered rosiglitazone, 10 mg/kg bolus, 30 min prior to cerulein); (c) Sham+saline group. Mice were treated with saline instead of cerulein; (d) Sham+Rosiglitazone. Identical to Rosiglitazone group except that the saline was administered instead of cerulein. Mice were killed at 6 h after the induction of pancreatitis. Blood samples, pancreas, and lungs were collected. MEASUREMENTS AND RESULTS: Infiltration of pancreatic and lung tissue with neutrophils was associated with enhanced lipid peroxidation. Immunohistochemical examination demonstrated a marked increase in immunoreactivity for nitrotyrosine and for ICAM-1 in the pancreas of cerulein-treated mice. In contrast, the degree of (a) pancreatic inflammation and tissue injury, (b) upregulation/formation of ICAM-1 and nitrotyrosine, and (c) neutrophils infiltration was markedly reduced in pancreatic tissue obtained from rosiglitazone-treated mice. CONCLUSION: These findings support the view that rosiglitazone and other potent PPAR-gamma agonists may be useful in the therapy of acute pancreatitis.     

按摩推拿学手法操作形式名称、功效与应用的规范化研究

目的探讨一指禅推法等五种手法的手法操作形式名称、功效与应用,以力求按摩推拿学手法的规范化表述。方法以10本按摩推拿学教材为研究对象,对教材中有关一指禅推法、拿法、按法、拨法、缠法的手法操作形式名称、手法功效和应用加以整理及采用单变量频数分布分析。结果在10本按摩推拿学教材中,一指禅推法共列出10种操作形式名称,按法11种,拿法5种,拨法6种。一指禅推法共列出23种功效,43个病（症）;按法21种功效,35个病（症）;拿法15种功效,24个病（症）;拨法5种功效,22个病（症）;缠法6种功效,7个病（症）。结论不同教材对按摩推拿学手法的操作形式名称、功效与应川的表述上存在着差异,应规范、统一手法表述,以利于按摩推拿学的普及及推广。