首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   102373篇
  免费   7971篇
  国内免费   2449篇
耳鼻咽喉   1587篇
儿科学   2314篇
妇产科学   1535篇
基础医学   4109篇
口腔科学   5451篇
临床医学   9440篇
内科学   11679篇
皮肤病学   1668篇
神经病学   5474篇
特种医学   2532篇
外国民族医学   32篇
外科学   16041篇
综合类   17444篇
现状与发展   10篇
一般理论   4篇
预防医学   6697篇
眼科学   2027篇
药学   8760篇
  189篇
中国医学   9024篇
肿瘤学   6776篇
  2024年   367篇
  2023年   1862篇
  2022年   3143篇
  2021年   4238篇
  2020年   4602篇
  2019年   3690篇
  2018年   3438篇
  2017年   3619篇
  2016年   3854篇
  2015年   3561篇
  2014年   6987篇
  2013年   9040篇
  2012年   6639篇
  2011年   7191篇
  2010年   6160篇
  2009年   5350篇
  2008年   4803篇
  2007年   5017篇
  2006年   4479篇
  2005年   3880篇
  2004年   3166篇
  2003年   2777篇
  2002年   2365篇
  2001年   1855篇
  2000年   1508篇
  1999年   1191篇
  1998年   985篇
  1997年   903篇
  1996年   753篇
  1995年   654篇
  1994年   583篇
  1993年   502篇
  1992年   421篇
  1991年   374篇
  1990年   275篇
  1989年   283篇
  1988年   265篇
  1987年   246篇
  1986年   212篇
  1985年   276篇
  1984年   223篇
  1983年   146篇
  1982年   203篇
  1981年   151篇
  1980年   132篇
  1979年   119篇
  1978年   67篇
  1977年   65篇
  1976年   50篇
  1975年   30篇
排序方式: 共有10000条查询结果,搜索用时 62 毫秒
81.
目的 探讨出血性脑室铸型的治疗方法与疗效。方法 分析脑室外引流、尿激酶脑室内注入、气管切开、控制血压以及脑积水的处理等多种治疗手段在治疗脑室铸型过程中的作用及其效果。结果 经过综合治疗完全恢复日常生活者10例(28.6%),部分恢复日常工作或独立进行家庭生活者13例(37.1%),生活需要照顾或护理者7例(20%),死亡5例(14.2%)。结论 对于出血性脑室铸型这类重症病人早期及时的脑室外引流是快速而有效的抢救措施,尿激酶脑室内注入对溶解血凝块,疏通脑室系统行之有效。气管切开对降低死亡率至关重要,控制血压是防止再出血的关键。脑积水的处理是康复过程中需要高度重视的环节。  相似文献   
82.
目的:提高原发性输尿管癌的术前诊断水平。方法:对南京医科大学第一附属医院1989-2002年间收治的31例原发性输尿管癌的临床资料进行回顾性分析。结果:31例中,肉眼血尿22例(71.0%),腰痛11例(35,5%)。B超、静脉肾盂造影(IVU)、CT和逆行造影检查的阳性率分别为输尿管腔内占位4例(13.0%)、输尿管腔内占位3例(11.5%)、膀胱或合并膀胱占位8例(36.4%),输尿管充盈缺损6例(40.0%)。29例患者经手术治疗,其中13例行患侧肾、输尿管、膀胱袖状切除。结论:老年患者反复发作的腰痛及血尿应考虑原发性输尿管癌的可能,造影诊断对本病有较高价值,应作CT及MRU无创检查。  相似文献   
83.
We present a case of benign osteoblastoma of the occipital bone. Benign osteoblastoma is an uncommon primary bone tumor, which usually involves the vertebrae and the long bones. This tumor rarely develops in the calvaria, showing a preference for the temporal and frontal bones when it does. To the best of our knowledge, this case is only the eighth reported case of benign osteoblastoma confined to the occipital bone. A 20‐year‐old male presented with a mild tender mass lesion of the occipital area, just below the lambda. Plain X‐ray films and CT scans demonstrated an osteolytic mass surrounded by the sclerotic rim within the diploic space. MRI proved to be effective for the evaluation of the intracranial and intraosseous extensions of the tumor. However, it was very difficult to formulate a differential diagnosis against other osteoblastic tumors, or osteoid osteoma, in view of its radiological appearance. The final diagnosis was obtained by careful consideration of the histopathological characteristics of the tumor combined with its clinical and radiological features. Although generally regarded as benign, a complete resection is preferred over conventional curettage as this can guard against possible recurrence and malignant transformation.  相似文献   
84.
Contemporary licensed treatments for multiple sclerosis fail to provide a solution for the disease because their effects are limited to a modest reduction in the frequency of new episodes. They do not reduce disability or materially influence the progressive phase of the disease. A contemporary strategy for management requires a more detailed analysis of the separate contributions to the clinical features and overall course made by inflammation, axonal injury, compensatory mechanisms, and remyelination. From this formulation emerges the need either for early and fully effective suppression of the inflammatory response, limiting the damage to all components of the axon-glial unit; or the development of strategies for axonal and myelin repair that solve the issues of controlled differentiation, delivery and timing of these cell and growth factor-based interventions.  相似文献   
85.
本文根据34例电击伤临床资料,分析早期处理与病人全身情况、局部损伤愈合以及并发症的关系.并讨论间生态组织的处理原则.结果表明:伤后1天内与伤后3天以上就诊的病人比较,前者全身情况良好,创面感染率低,局部损伤用皮瓣或(和)皮片覆盖效果满意,并发症及截肢率均较低  相似文献   
86.
87.
Abstract Economic factors in diagnosis and treatment planning in periodontology may be considered from several points of view. A first perspective is that of government responsibility. Because of the explosion in health care expenditure in the last decade, public funding of dental care programmes may become static or even reduced. Most governments try to curb the ever growing public health expenditure. Consequently, terms like effectiveness, efficiency and accountability are now becoming common words also in relation to periodontal health care. Moreover, private insurance companies, which have entered this area, may be individual patient who, explicitly or implicitly, would like to consider the services individual patient, who explicitly or implicitly, would like to consider the sendees rendered in periodontal therapy and prevention as cost-effective. Features of supply of and demand for care on an individual basis should also be considered. Finally, the periodontist or general practitioner has to consider economic factors. In professional life, there should be a balance between good working conditions providing satisfactory care, and the demands and priorities of individual patients and the community at large.  相似文献   
88.
Background: The aim of this study was to evaluate the effects of azithromycin on mucocutaneous manifestations, oral health and immune response in Behçet's disease (BD). Methods: Eight BD patients with active mucocutaneous symptoms were treated with azithromycin for 4 weeks. Oral health, clinical manifestations and in vitro interleukin (IL)‐12, interferon (IFN)‐γ, IL‐10 and monocyte chemotactic protein (MCP)‐1 responses were evaluated before and after treatment. Results: The number of folliculitic lesions, healing time of oral ulcers and scores of plaque indexes (PLIs) were lower after azithromycin treatment (P < 0.05). Scores of PLIs correlated positively with the healing time of oral ulcers (P = 0.02). Although a trend towards increased stimulated IL‐10 responses with azithromycin was observed, no statistically significant difference was found. Stimulated and unstimulated MCP‐1, IFN‐γ and IL‐12 responses were similar before and after treatment (P > 0.05). Conclusion: Azithromycin was observed to be effective in decreasing folliculitic lesions and fastening the healing time of oral ulcers in BD.  相似文献   
89.
Summary: It is not generally appreciated that intractable seizures involving the face area are amenable to surgical treatment. Twenty patients with onset of sensorimotor seizures in the face area of the pre- and postcentral gyri have been studied and surgically treated since 1948. Seizures started in the face, tongue, or throat, followed by diverse patterns depending on spread of seizure activity. Two patients had epilepsia partialis continua; 6 had either tonic or atonic drop attacks. All patients had pre- and postcentral face area resections, 12 in the dominant hemisphere. In addition, 3 had more extensive postcentral removal, 7 had temporal lobe, and 4 had small separate or contiguous frontal or parietal resection. Because the seizures were not sufficiently reduced by the first operation, 6 required reoperation; 4 of these patients had residual epileptiform activity on electrocorticogram (ECoG) after the first resection. Three patients had new neurologic signs that did not return to the preoperative level, but in 2 of them the deficit related mainly to higher resection in the central area. All but 2 of these 20 patients had at least moderate seizure reduction. Corticectomy can be performed for treatment of seizures arising in the lower central area and usually does not lead to significant permanent neurologic deficit.  相似文献   
90.
The Childrens Cancer Study Group evaluated daily oral 13-cis-retinoic acid to determine its therapeutic efficacy in 28 children with advanced neuroblastoma refractory to conventional therapy. Cheilitis and fissured lips were the most common side effects; however, fewer than 50% of the patients experienced any toxicity. Two of twenty-two evaluable children demonstrated positive response to therapy. In one case, a child received the drug for 11 months. Seventeen patients demonstrated progressive disease within 28 days of the start of treatment. Three other patients with stable disease, or removed from study at day 28, were considered nonresponsive. Our data demonstrate that, when given as a single daily oral dose of 100 mg/m2, 13-cis-retinoic acid does not have significant activity in children with advanced neuroblastoma. © 1992 Wiley-Liss, Inc.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号