珠海市横琴岛嗜人按蚊生态习性研究

目的:研究珠海市横琴岛嗜人按蚊的生态习性。方法:蚊媒调查方法。结果:横琴岛嗜人按蚊主要孳生于水质清凉、遮阴良好的淡水沟溪及有丰富水体的香蕉地和甘蔗地等。属人、牛血兼吸品种，趋吸人血比例为76、34％，吸血后外逸比例为92、77％，夜间吸血活动高峰在午夜后至次日清晨，全年高峰季节在8～10月。结论:该地嗜人按蚊有人、牛血兼吸，趋吸人血比例较大陆品种低，偏野栖，夜间吸血活动持续时间长，全年活动高峰季节长的生态特点。     

侧脑室脑膜瘤的诊断及显微手术治疗

目的 探讨侧脑室内脑膜瘤诊断特点及显微手术方法.方法 MRI和/或CT确诊并行显微手术切除侧脑室脑膜瘤24例,其中2例内窥镜辅助切除.肿瘤位于左侧三角区13例,右侧三角区7例,右侧体部1例,横跨双侧三角区1例,左侧颞角2例.顶枕入路15例,颞中回入路7例,经胼胝体后部入路2例.结果 24例影像学诊断与术后病理相符合,均给予全切.完整切除5例,分块切除19例.18例获得随访,完全正常10例,3例复发再次手术全切,癫痫2例,同向性偏盲3例.结论 CT和MRI是诊断侧脑室脑膜瘤的最可靠的手段,显微手术是目前侧脑室脑膜瘤的首选治疗方法.     

Quantitative relationship between pupillary reflex feature and its diopter in retinoscopy

ＱｕａｎｔｉｔａｔｉｖｅｒｅｌａｔｉｏｎｓｈｉｐｂｅｔｗｅｅｎｐｕｐｉｌｌａｒｙｒｅｆｌｅｘｆｅａｔｕｒｅａｎｄｉｔｓｄｉｏｐｔｅｒｉｎｒｅｔｉｎｏｓｃｏｐｙＸｕＳｈａｎｇ（徐上）；ＪｉＳｈａｎｇｎｉａｎ（计尚年）（ＤｅｐａｒｔｍｅｎｔｏｆＯｐｈｔｈ...     

Spectrometric investigations in ocular hypertension and early stages of primary open angle glaucoma and of low tension glaucoma — multisubstance analysis

The approximation of logarithmic difference spectra between the reflectance of the normal fundus and the fundus reflectance in different stages of glaucoma is demonstrated by a model. The influences of fundus pigments like oxihemoglobin, melanin, xanthophyll and rhodopsin as well as the intensity and the exponent of the scattered light are optimized. Glaucomatous alterations in the extinction of these pigments and of the scattering parameters are different in the macula, in the papillo-macular bundle and in the parapapillary region temporal to the optic disc. A lack of oxihemoglobin only in the papillo-macular bundle in first relative losses in the visual field function points to a damaged microcirculation in early POAG. In progressive glaucoma the extinction spectrum of xanthophyll is detectable in the papillo-macular bundle. A decreased intensity of the scattered light and an altered scattering exponent are suggestive of a damage in the nerve fiber layer at early stages of glaucoma.     

类风湿性关节炎的肺部表现

本文对30例类风湿性关节炎患者中合并肺部损害的6例患者进行报道。其肺部的主要临床表现为胸痛、咳嗽、气短、长期低热及呼吸困难。体征主要为肺部干湿性罗音及胸膜摩擦音。胸部X线检查可见胸腔积液、胸膜肥厚粘连，弥漫性间质性肺纤维化、间质性肺炎。实验室检查可有嗜酸性粒细胞增高、类风湿因子阳性、血沉增快、免疫球蛋白增高等。本文并对类风湿性关节炎合并肺部病变的发生机理进行了初步探讨。     

Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production—Flow cytometry and mathematical modeling

Cell culture-based influenza vaccine manufacturing is of growing importance. Depending on virus strains, differences in infection dynamics, virus-induced apoptosis, cell lysis and virus yields are observed. Comparatively little is known concerning details of virus–host cell interaction on a cellular level and virus spreading in a population of cells in bioreactors. In this study, the infection of MDCK cells with different influenza A virus strains in lab-scale microcarrier culture was investigated by flow cytometry. Together with the infection status of cells, virus-induced apoptosis was monitored. A mathematical model has been formulated to describe changes in the concentration of uninfected and infected adherent cells, dynamics of virus particle release (infectious virions, hemagglutinin content), and the time course of the percentage composition of the cell population.     

急性病毒性心肌炎的发病机制和临床特征

急性病毒性心肌炎是由病毒侵犯引起心肌本身的病变,包括病毒感染对心肌的损害、细胞免疫以及多种细胞因子等介导的心肌损害和微血管损伤。这些变化损害心脏功能和结构,而危及生命。且近年发病呈逐年上升趋势,其发病症状隐匿突然,加重了其危害性。本文就急性病毒性心肌炎发病机制和临床特征进行总结。     

Dynamics of ablation plume particles generated during excimer laser corneal ablation

Background and Objective: Although the empirical characteristics of ArF excimer laser corneal ablation have been well documented, the exact ablation mechanisms are not well understood. The present paper reports a quantitative analysis of corneal ablation plumes using in situ time resolved laser light scattering and Raman spectroscopy. Study Design/Materials and Methods: Bovine corneas were used as the ArF excimer laser ablation targets. Light scattering data were recorded from the ablation plume as a function of height above the tissue surface and as function of delay time with respect to the ablative ArF laser pulse. Results: Raman spectra of the ablation plume allow identification of the particles as water. Mean plume particle diameters are found to decrease with height, while the particle volume fractions are relatively constant. The total volume of plume particles correlates well with the total volume of water in the ablated corneal tissue. Conclusion: The finding of a non-evolving plume composed of water spherules, combined with the excellent agreement between total volume of water in the plume and the content of water in the ablated corneal tissue, support the concept of photodecomposition or “cold ablation” for corneal tissue during ArF excimer laser ablation. © 1995 Wiley-Liss, Inc.     

37例传染性非典型肺炎流行病学调查与讨论

目的了解传染性非典型肺炎(SARS)流行病学的特点,提出相应的预防和控制措施.方法采取现场调查、网上电子病历审查、电话询问等方法.结果37例SARS患者的治愈率为89.2%,病死率8.1%,有接触史患者占37.8%.由于执行了严格的消毒隔离制度,医院内无任何人员感染发病.结论SARS患者在年龄上以青壮年为多,职业类以商业餐饮食人员为多.     

A small angle light scattering device for planar connective tissue microstructural analysis

The planar fibrous connective tissues of the body are composed of a dense extracellular network of collagen and elastin fibers embedded in a ground matrix, and thus can be thought of as biocomposites. Thus, the quantification of fiber architecture is an important step in developing an understanding of the mechanics of planar tissues in health and disease. We have used small angle light scattering (SALS) to map the gross fiber orientation of several soft membrane connective tissues. However, the device and analysis methods used in these studies required extensive manual intervention and were unsuitable for largescale fiber architectural mapping studies. We have developed an improved SALS device that allows for rapid data acquisition, automated high spatial resolution specimen positioning, and new analysis methods suitable for large-scale mapping studies. Extensive validation experiments revealed that the SALS device can accurately measure fiber orientation for up to a tissue thickness of at least 500 μm to an angular resolution of∼1^o and a spatial resolution of±254 μm. To demonstrate the new device’s capabilities, structural measurements from porcine aortic valve leaflets are presented. Results indicate that the new SALS device provides an accurate method for rapid quantification of the gross fiber structure of planar connective tissues.