中国健康中青年女性全血比粘度参考值与海拔高度的关系

目的：为制定中国健康中青年女性全血比粘度参考值的统一标准提供科学依据。方法：收集了中国各地用毛细管法测定的健康中青年女性全血比粘度参考值,并对其与海拔高度的关系进行了研究。结果：发现随着海拔高度的逐渐增大,健康中青年女性全血比粘度参考值也在逐渐增大,相关性很显著。用一元回归分析的方法推导出一个回归方程。结论：如果知道了中国某地的海拔高度,就可以用回归方程估算这个地区的健康中青年女性全血比粘度参考值。     

采用测量溯源理论和方法建立中药质量保证体系

中药及相关产业具有巨大的开发潜力和发展前景，已成为全世界新药开发和医药产业发展的方向之一。我国中药质量标准体系的建立是中药现代化首先解决的关键问题之一，为了保证各实验室检测数据准确、可靠、可比、互认，需要以国际上测量溯源理论和方法为依据，加强政府和中药管理部门对中药及相关产业的标准、法律法规等的建设，使中药质量保证体系与国际接轨，保护我国的经济利益、人民健康和广大消费者的利益不受损害。     

痔克胶囊的研制与临床应用

目的：研制以壁虎为君药的痔克胶囊,观察其临床疗效.方法：制定制备工艺及质量标准,观察63例痔疮患者口服该方的疗效.结果：该药采用薄层层析法鉴别君药,方法简便可行.含量测定方法平均回收率99.6%,RSD 2.18%.Ⅰ期内痔显效率100.0%,Ⅱ期内痔62.5%,Ⅲ期内痔40.0%.结论：该药组方合理,质控方法可靠,疗效显著.     

瓜蒌中有机氯农药残留量的含量测定

 目的 对中药瓜蒌进行有机氯农药的残留量测定，开展瓜蒌质量标准的规范化研究。方法 采用气相色谱法对六六六（BHC）4种异构体、滴滴涕（DDT）4种异构体和五氯硝基苯(PCNB)进行测定。结果 11个瓜蒌样品中六六六的总含量位于2.86～21.85 μg·kg^-1的范围，滴滴涕的总含量位于2.86～50.04 μg·kg^-1的范围，五氯硝基苯的含量低于4.94 μg·kg^-1。结论 所测瓜蒌中农药残留量低于我国国家相关的规定限量；样品中商品瓜蒌的农药残留量高于非商品瓜蒌的残留量，提示我们在瓜蒌的贮存、运输等过程中应该限制农药的污染。     

以前胡为例,探讨中药活性成分研究的思路与方法

前胡为中国药典收载的常用中药，我们在对其化学成分和生物活性深入系统研究的过程中，逐渐形成了对中药活性成分研究思路和方法的认识。本文主要结合我们长期的研究工作，综述了1993年后中药前胡在化学成分、质量标准、资源开发、有效成分的结构修饰与全合成以及药理活性方面的研究近况，其主要目的是介绍如何以前胡活性成分研究为基础，全面提高中药前胡的研究水平，并为新药开发奠定基础。对前胡的研究已初步建立起了活性成分的现代化研究模式，期望其研究思路与方法能为其它中药活性成分的研究提供参考。     

Diagnosis: toxic!--trying to apply approaches of clinical diagnostics and prevalence in toxicology considerations.

The assessment of relevance of toxicological testing was compared with approaches of diagnostic medicine, a discipline that faces a comparable situation. Considering the work of a toxicologist as setting a diagnosis for compounds, assessment tools for diagnostic tests were transferred to toxicological tests. In clinical diagnostics, test uncertainty is well accepted and incorporated in this assessment. Furthermore, prevalence information is considered to evaluate the gain in information resulting from the application of a test. Several common toxicological scenarios, in which test uncertainty and prevalence are combined, are discussed including the interdependence of test accuracy, prevalence and predictive values or the sequential application of a screening and a confirmatory test. In addition, real prevalences derived from prevalences determined by an imperfect test are presented. We conclude that information on prevalences of toxic health effects is required to allow a complete assessment of the relevance of toxicological test. In this process, lessons can be learned from evidence-based approaches in clinical diagnostics.     

''I found myself to be a down to earth Dutch girl'': a qualitative study into learning outcomes from international traineeships

OBJECTIVE: To explore learning outcomes from international traineeships for undergraduate medical students. METHODS: In-depth interviews were conducted with 24 undergraduate medical students at Maastricht University Medical School, The Netherlands. The 24 subjects were selected by purposeful sampling. RESULTS: Students reported meaningful learning outcomes in 6 domains: medical knowledge; skills; international health care organisation; international medical education; society and culture, and personal growth. DISCUSSION: International traineeships appear to provide good opportunities for students to meet the requirements of globalisation as well as some of the generic objectives of undergraduate medical education. The tentative findings of this study need to be confirmed by further studies.     

Quality of Life in the General Norwegian Population, Measured by the Quality of Life Scale (QOLS-N)

The main aim of the present study was to derive norms or reference values from the general Norwegian population for the Norwegian version of the Quality of Life Scale (QOLS-N). In addition, associations between socio-demographic and health variables on the level of quality of life were examined. The sample consisted of 1893 subjects from a total of 4000 randomly selected Norwegian citizens representative of the entire Norwegian population, aged 19-81. The subjects received a mailed questionnaire containing the QOLS-N. Results show that the mean quality of life score was 84.1 (SD 12.5). Women reported a higher quality of life than men. People with higher levels of education reported a higher quality of life. Those who were married or cohabitating reported the highest quality of life and those who were unemployed reported a lower quality of life than those who worked. In addition, people reporting long-term diseases or health problems scored significantly lower on quality of life. These results could serve as reference values for the level of quality of life, as measured by the QOLS-N in the Norwegian population.     

中韩国际客运班轮航线卫生检疫监督结果分析

目的总结经验,提高工作质量,促进中韩客运班轮航线出入境卫生检疫监督工作顺利开展。方法对秦皇岛至仁川中韩国际客运班轮航线通航一年来出入境卫生检疫监督工作情况进行总结和分析,对存在的问题提出完善和改进措施。结果在入出境卫生检疫监督、旅客携带物品检疫查验和旅检现场设施等方面均发现和存在较多的问题及不足,特别是船舶输入性医学媒介生物和国际带工携带违禁物品等方面更加突出,表明中韩航线存在疫情疫病传入等巨大潜在风险。结论建议制定统一完善的中韩客运班轮航线出入境卫生检疫监督工作标准和操作规程,开展人员培训和业务交流,提高工作质量,达到有效防止疫情疫病和其他危害因素传入传出的目的。