Biological effects of static magnetic fields on the microcirculatory blood flowin vivo: a preliminary report

There have been few studies of the effect of static magnetic fields on microcirculatory haemodynamics in vivo. The rat skinfold transparent chamber technique was used, which provides an excellent means of observing and quantifying direct in vivo microvascular haemodynamic responses to static magnetic fields up to 8 T. An intravital videomicroscope was used to measure the changes in blood flow before and after exposure to a magnetic field for 20 min in a horizontal type superconducting magnet with a bore 100 mm in diameter and 700 mm long. After exposure, microcirculatory blood flow showed an initial increase for about 5 min followed by a gradual decrease and a return to the control value. It is hypothesised that these changes represent rebound hyperaemia following reduced blood flow during exposure.     

红外多波长无创人体血糖检测阵列模型的研究

无创血糖监测不仅可以减少患者的痛苦，还能进行连续测量，从而降低并发症的发生，它是一种不需收集血样进行体内血糖浓度测量的新技术。本文根据朗伯-比尔定律(The Lambert—Beer Law)原理，为克服无创血糖检测研究中的难点和缺陷，详细分析了血糖红外光谱的吸收特性，利用阵列技术设计了红外多波长无创血糖检测传感器阵列模型，对关键技术进行了讨论。用ME算法建立了信号检测和标定数学模型，结合了人体各种影响因素，使红外无创血糖检测的精度和稳定性得到了改善。列举了详细的实验实施步骤，同时叙述了系统调试的详细过程，讨论了无创血糖检测中需要注意的问题。     

Repeatability of measuring knee flexion angles with wearable inertial sensors

Background

As assessment with inertial-measurement-units (IMUs) increases in research and in clinics, it is important to be aware of the repeatability of these sensors. The objectives of this experiment were to evaluate the measurement repeatability of IMU joint angles using a repeatable robot controller and an anthropomorphic leg phantom and to determine effects of joint speed and sensor positioning on the angles collected by these sensors. Comparisons to an electro-goniometer and three-dimensional (3D) motion capture cameras were also completed.

多气阀数字血压计的研制

本文研制的袖套式数字血压计，基于示波法原理，通过采用多通道、多气阀以及软件上的改进，改善了目前一般数字血压计的不足，与一般袖套式数字血压计相比，具有重复性好、测量范围大（成人和儿童都可测量）等优点。     

Direct blood-pressure measurements: risks,technological evolution and some current problems

The direct measurement of blood pressure has found widespread use in intensive care units, operating rooms, and in emergency departments. Infection, air embolism and thrombosis are some of the risks to patients associated with both the cannulation procedure and with the apparatus used in the blood-pressure measuring process. Although there is constant revision in an attempt to reduce these risks, they cannot be completely eliminated. The need for direct blood-pressure measurements and the physiological effects of air embolism and thrombosis are reviewed. Infection and problems related to the techniques used to insert the catheters are not discussed.     

利用脉搏波特征参数连续测量血压的方法研究

通过研究血压与脉搏波特征参数的关系，提出了一个选择多个与血压相关的脉搏波特征参数,通过回归分析建立适合不同人的特征方程，进行血压的连续测量的新方法，为了验证测量结果的准确性；研制了张力计。实验结果表明：该方法具有较高的测量精度，可以应用于临床危重病人的血压监护和一般医学研究中，经过进一步地改进和完善后可应用于载人航天和日常动态环境。     

乙型肝炎病毒核酸定量检测中不确定度的研究

目的研究应用实时荧光定量PCR（Fluorescence Quantitative PCR,FQ-PCR）开展乙型肝炎病毒（Hepatitis Bvirus,HBV）核酸定量检测中的测量不确定度。方法通过实时荧光定量PCR进行乙型肝炎病毒核酸定量检测的实验分组设计与数据处理分析,计算分析该检测方法不同来源的测量不确定度值。结果对3组不同水平浓度值样本来源的数据采用两种方法进行统计分析,QDNA的组标准差远远大于LGQDNA的标准差,初始浓度数值经过对数转化后离散程度降低,统计平均值也发生了偏离。LGQDNA为3.465、4.927和6.018的样本,其浓缩过程来源的相对不确定度分别为0.020、0.019和0.009;LGQ无偏估计在3.706、6.750的样本的核酸提取来源相对不确定度分别为0.016和0.009;数据分析来源的LGQ不确定度为0.000～0.008;热循环仪来源的LGQ不确定度为0.002～0.008。结论使用核酸浓度值QDNA与使用其对数值LGQDNA进行数据统计分析的结果存在差异;标本制备过程中的浓缩和DNA提取是实时荧光定量PCR进行HBV核酸定量检测时测量不确定度的重要来源,标本制备环节是影响该项检测的关键因素,包括试剂、方法和操作者的准确操作能力。     

耳穴静态电测量中的瞬变响应

耳穴电参数时变关系实验表明，在测量起始ｔ＜２τ时，因瞬变作用，电位Ｅ（ｔ）和压降Ｕ（ｔ）为瞬态响应，响应函数呈指数关系，特征参数为弛豫时间τ，τ≈ＲＣ；ｔ＞２τ时，为时变间期。电路分析给出数学描述，并与耳穴和模拟实验结果较相符。提示，时变特征应以ｔ＞２τ后提取，静态电测量时，采样应避开瞬变期，可提高准确性。该工作对正确鉴别时变性和特征提取，全面认识耳穴电特性具有重要意义。     

New image-processing system for analysis,display and measurement of static and dynamic foot pressures

A new image-processing system, using a video digitiser with an IBM-compatible PC/AT, is developed for acquisition and processing of low-contrast, lowintensity barographic images of both feet for assessment of pressure distribution during standing and walking. Data displays, in the form of centres of pressures, isopressures contours, perspective views of pressures, grey scale image and walking pressure patterns, combined image of walking pressures, paths of centres of pressures and pressure variations with time, are developed. These have provided very useful and early information regarding the internal structural changes in the bones of the foot and sites at risk of ulcer development in leprosy subjects and enable suitable corrective orthopaedic procedures to be adopted. unitl the end of November 1990, and will then return to the Indian Institute of Technology.