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91.
真皮下血管网皮瓣修复感染创面的研究 总被引:2,自引:0,他引:2
目的:探讨真皮下血管网皮瓣的抗菌能力和临床修复感染创面的应用。方法:以家猪为实验动物,在臀部两侧分别形成传统的岛状皮瓣和真皮下血管网岛状皮瓣,用细菌计数、吖啶橙荧光染色测定白细胞吞噬指数和白细胞内杀菌率等方法,进行对比。结果:真皮下血管网岛状皮瓣的抗菌力明显降低。 1989年起临床应用 5例,创面彻底清创后用吻合血管的真皮下血管网游离皮瓣修复,全部成活。结论:该皮瓣抗菌力虽低于传统皮瓣,但仍可用于修复感染创面。 相似文献
92.
用神经网络法预测药物在体透过人皮肤的渗透性 总被引:4,自引:2,他引:2
傅旭春 《浙江大学学报(医学版)》2003,32(2):152-154,158
目的:预测药物在体透过人皮肤的渗透性。方法:以正辛醇/水分配系数(logP)、分子体积(V)、氢键酸度(∑β2^H)和氢键碱度(∑β2^H)等理化参数作为输入层神经元,以药物在一定时间内在体透过人皮肤的透过比的对数值(R,透过量/未透过量)作为输出层神经元,建立起合适的BP(Back—propagation)神经网络。结果:17个药物在一定时间内在体透过人皮肤的透过比的神经网络计算值和实测值均相当符合。结论:用BP神经网络法可以较好地预测药物在体透过人皮肤的渗透性。 相似文献
93.
应用计算机网络系统提高门急诊管理水平 总被引:3,自引:0,他引:3
作者介绍的门急诊计算机管理网络系统,应用软件使用FOXPRO2.5FORDOS语言,在两台网络服务器之间应用镜像技术,门诊号的录入使用光笔和条形码技术,实行划价、收费一体化,采用星型拓扑网络结构,保证了网络的先进性、安全性、稳定性和可扩充性。网络系统实现挂号、划价收费、调剂、药品使用管理、工作量统计及经济核算的全程闭环管理格局,有效地堵塞了管理和经济上的漏洞,提高了工作效率和管理水平。该系统已正常运行了12个月,并通过省级科技成果鉴定。 相似文献
94.
沈备娟 《浙江中医药大学学报》2007,31(4):519-519,522
在青年学生中吸收优秀分子已成为高校党组织发展工作的重要组成部分,最近几年来,高中党建工作也不断发展。了解青年学生党建现状,更好地利用中学党建工作成果,提出了做好衔接工作的现实意义及对策措施。 相似文献
95.
Objective: Effective material exchange between blood and tissue depends on the heterogeneity of microvascular flow. The objective was to address inconsistencies between intravital studies regarding this dependency. We tested the hypothesis that heterogeneity of red blood cell velocity (VRBC) in capillary beds varies with the strength of metabolic stimulus and with capillary bed geometry. Methods: We used videomicroscopy to measure VRBC in a bed of 10–24 capillaries at the surface of extensor digitorum longus (EDL) muscle in anesthetized rats. The coefficient of variation (CV = standard deviation/mean; an index of spatial heterogeneity) was computed in the same bed before and after (i) 1, 2, 4, or 8 Hz supramaximal muscle contraction or (ii) adenosine superfusion (10?7–10?3 M). Beds with or without arteriolar—venular capillary shunts were used. Results: Although control VRBC differed between beds (shunt: 232 μm/s; no shunt: 130 μm/s), the percentage increases in postcontraction VRBC did not (range: 111–326%). In both beds, control CV varied greatly (overall range: 28–117%) and 2–8 Hz muscle contractions reduced CV significantly by 25%. Similar results were obtained for adenosine. In confirmatory experiments using the rat cremaster muscle, contractions (4 Hz) and adenosine (10?4 M) also reduced CV. Based on all data, CV = 63–0.022 VRBC (r = 0.82, P < 0.001). Conclusions: The heterogeneity of VRBC decreased with metabolic stress, regardless of capillary bed geometry. We propose that both the large variability in control CV and the relatively shallow dependence of CV on velocity could be responsible for the present inconsistencies between intravital studies. 相似文献
96.
Objective: To explore patterns in the practice of nursing and patient outcomes.
Design: Qualitative field research.
Population, Sample, Setting: Populations were critical care nurses and critically ill adult patients in the 10-bed medical critical care unit of a 900-bed teaching hospital. A convenience-purposive sample of 27 nurses and 31 patients was studied in 1985.
Methods: Six months of participant observation, unstructured interviews, and the constant comparison method of grounded theory.
Findings: Markedly different patterns were found in expert and nonexpert practice. The substantive theory of conversion helped explain how the majority of nonexpert nurses advanced their practice. The metaphor of catalyzed conversion captures how a unit-based expert nurse serves as a catalyst to advance the practice of nonexperts. Presence, defined as the way of being within a given clinical context, differentiated nurses.
Conclusions: (a) Expert and nonexpert practices are substantively different, (b) Expert and nonexpert practice results in different patient outcomes, (c) Conversion helps explain changes in nonexpert practice.
Clinical Implications: A unit-based expert nurse can increase patient-focused care. 相似文献
Design: Qualitative field research.
Population, Sample, Setting: Populations were critical care nurses and critically ill adult patients in the 10-bed medical critical care unit of a 900-bed teaching hospital. A convenience-purposive sample of 27 nurses and 31 patients was studied in 1985.
Methods: Six months of participant observation, unstructured interviews, and the constant comparison method of grounded theory.
Findings: Markedly different patterns were found in expert and nonexpert practice. The substantive theory of conversion helped explain how the majority of nonexpert nurses advanced their practice. The metaphor of catalyzed conversion captures how a unit-based expert nurse serves as a catalyst to advance the practice of nonexperts. Presence, defined as the way of being within a given clinical context, differentiated nurses.
Conclusions: (a) Expert and nonexpert practices are substantively different, (b) Expert and nonexpert practice results in different patient outcomes, (c) Conversion helps explain changes in nonexpert practice.
Clinical Implications: A unit-based expert nurse can increase patient-focused care. 相似文献
97.
S. N. Sarbadhikari 《Medical engineering & physics》1995,17(8):579-582
The use of an artificial neural network (ANN) system to differentiate the EEG power density spectra in depressed from normal rats was tried. The beneficial effects of chronic physical exercise in reducing the effects of stress and therefore depression was also to be tested in animals by the same method. In this study, rats were divided into 4 groups, subjected to (i) chronic stress (D group); (ii) chronic exercise by treadmill running (EO group); (iii) exercise with stress (ES group) and (iv) handling (C group). The prefrontal cortical EEG, EMG and EOG were recorded simultaneously on paper and the digitized EEG signals were also stored in the hard-disk of a PC-AT through an ADC. After filtering the digitize signals, the EEG power spectra were calculated by an FFT routine. Three successive 4 s artefact-free epochs were averaged. The REM and NREM sleep periods as well as the awake period signals were analyzed separately. The FFT values from each of the 3 states, in the 4 groups of animals were tested by an ANN with 30 first layer neurons and a 2nd layer of a majority-vote-taker. The ANN could distinguish the depressed from the normal rats' EEG very well in REM (99%) sleep, NREM (95%) sleep and awake (81%) states. In most of the cases it identified the exercised rats' EEG as normal. 相似文献
98.
目的 探索医学生团队对大学英语思政教学资源的发掘与整合,并建设医学院校大学英语课程思政教学资源库,为医学生英语教学与思政教育的融合提供可行性经验。方法 对某医学院校1 030名学生进行问卷调查,并采用SPSSAU统计软件对调查结果进行分析,了解学生对英语教学与思政教育融合的态度与需求、大学英语思政教学资源库的建设方式,以及资源的呈现方式和类型。基于问卷结果、教材主题、教学模块与学生专业,采用内容分析与归类法,建设符合医学生期望的大学英语思政教学资源库。数据均以占比百分率的形式呈现。结果 ①836名学生认为大学英语有必要与思政教育融合,希望通过日常生活(731人)、医学背景知识(664人)、社会实践(622人)、新闻时事(604人)等相关的视频、音频建设思政资源库,并以“教师讲授+课堂讨论”(528人)的形式引导学生学习上述资源。②根据教材主题匹配问卷结果中的思政融入点,根据单元模块内容进一步细化思政融入点为普适性与医学专属思政教学元素两类,最终建成了医学院校大学英语思政教学资源库。结论 好的课程与资源是师生共研共建的。 相似文献
99.
100.