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排序方式: 共有10000条查询结果,搜索用时 46 毫秒
31.
I. DILEK N. TOPCU C. DEMIR A. BAY K. UZUN A. GUL A. FAIK
NER S. UGRAS 《International journal of laboratory hematology》2006,28(3):170-176
The incidence of hematological malignancies during pregnancy is low, and treatment in this setting is problematic. This study observed 21 pregnancies in 18 patients with hematological malignancies. Patients’ ages were between 19 and 43 (median 25) years. Two pregnancies ended with spontaneous abortion, one pregnancy ended with in utero death, three therapeutic abortions were carried out, and 15 infants were born alive but three of them died later. The median birth weight was 2.47 kg. Twelve babies survived to a median age of 36 (range 4–117) months. Eight babies were exposed to chemotherapy during the in utero period. One baby was exposed to chemotherapy during all the trimesters and was born prematurely and later died because of intracranial bleeding. Four babies were exposed to chemotherapy during the first trimester, one of them had low birth weight and floating thumb malformation, two of them had only low birth weight, and one was born healthy, but died at 3 months of age as a result of severe gastroenteritis. Two babies were exposed to chemotherapy during the second and third trimesters; one of them had low birth weight, and the other pregnancy ended in in utero death. One infant was exposed to chemotherapy during the third trimester and was born at term, but died because of pulmonary hemorrhage. We concluded that chemotherapy during all trimesters of pregnancy carries a significant risk for an unfavorable outcome. 相似文献
32.
Bernard–Soulier syndrome (BSS) is a rare autosomal recessively inherited bleeding disorder. Pregnancy in patients with BSS is characterized by ante‐, intra‐, or postpartum haemorrhage, which may be delayed and severe. There is no consensus in the management of BSS in pregnancy and so far only 16 pregnancies in nine patients have been described. We report a further three pregnancies in two women with the syndrome. We also outline our management of pregnant patients with BSS. 相似文献
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34.
P G Crosignani A M Mattei C Scarduelli V Cavioni P Boracchi 《Human reproduction (Oxford, England)》1989,4(8):910-912
This paper reports the changes in prolactin levels after 12 spontaneous and 52 induced pregnancies in 54 women with unambiguous hyperprolactinaemia (median plasma prolactin levels 67.5 ng/ml, range 40-400). Twenty-three of the patients showed radiological evidence of prolactinoma. The pregnancies were induced in 37 patients by bromocriptine, in nine by metergoline, in two by lisuride and in four by other treatments. Of the 64 pregnancies, 16 ended in spontaneous abortion, while 48 went to term. Follow-up was continued for at least 6 months after delivery or until the end of lactation. In a control group of 32 hyperprolactinaemic women (median prolactin 70 ng/ml, range 40-400) not wishing to become pregnant, prolactin changes were similarly registered over a mean period of 15 months without any treatment (range 6-38 months). After pregnancy, a significant downward trend of plasma prolactin was observed in the puerperal women with a 'normalization' rate of 17%. No changes were observed in the 32 controls who did not become pregnant. 相似文献
35.
妊娠合并肝内胆汁郁积症的围生儿结局57例分析 总被引:1,自引:0,他引:1
目的 探讨妊娠合并肝内胆汁郁积症(ICP)患者致围生儿不良结局的相关指标。方法 总结本院57例ICP患者的相关临床资料,将其与围生儿结局进行分组对照分析。结果 血清胆汁酸升高与围生儿不良结局关系不明显(P>0.05);血清转氨酶水平在产生围生儿不良结局组与未产生围生儿不良结局组之间有显著性差异(P>0.01);皮肤瘙痒持续时间大于3周组围生儿不良结局发生率与持续时间小于3周组有显著性差异(P<0.05);有、无NST基线变异消失组的围生儿不良结局发生率有极显著性差异(P<0.01)。结论 血清转氨酶水平、皮肤瘙痒持续时间及NST基线变异是否消失是预示围生儿不良结局的相关指标。 相似文献
36.
非孕期子宫肌瘤红色变性40例分析 总被引:2,自引:0,他引:2
目的 了解非孕期子宫肌瘤红色变性的临床特征。方法 本组回顾分析了1993年1月~2001年2月间住院手术治疗40例非孕期子宫肌瘤红色变性的临床病理特征。结果 非孕期子宫肌瘤红色变性发生率为2.3%。生育年龄多见,绝经后也可发生。有典型表现者2例,占5%,非典型下腹隐痛而无发热者7例,占17.5%,肌瘤结节局部压痛者12例,占30%,无任何症状者30例,占75%,白细胞升高占10例,25%。90%的红色变性肌瘤直径在5cm以上,77.5%为壁间肌瘤。68.6%有典型牛肉样改变,54.8%旋涡状结构存在。65%为单纯红色变性,余35%可合并其他类型变性。结论 非孕期子宫肌瘤红色变性临床过程缓和,症状不典型,易漏诊,不作为手术指征,但因子宫肌瘤往往较大,多需手术治疗。 相似文献
37.
特殊部位异位妊娠的临床分析 总被引:1,自引:0,他引:1
目的探讨特殊部位异位妊娠的临床特点,误诊原因及治疗原则。方法对1996年1月至2003年12月诊治的256例特殊部位异位妊娠进行回顾性分析。结果特殊部位异位妊娠发生率占同期异位妊娠的3.36%,术前诊断率48.4%,所有的患者均行手术。视术中情况进行不同的处理,所得标本均经病理切片证实,全部患者愈后良好。结论特殊部位异位妊娠的临床表现不典型,容易漏诊误诊,一旦怀疑本病应尽早住院,及时明确诊断并手术,患者愈后良好。 相似文献
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40.
ABSTRACT. Serum concentrations of sulphasalazine and sulphapyridine were measured during the first week of life in 15 children whose mothers had been on sulphasalazine during pregnancy. The serum concentrations of sulphapyridine and sulphasalazine were similar in the children and their mothers at delivery. The elimination rate of the drugs in the newborn children was slow but the concentrations were not so high that a bilirubin displacing effect could be expected. In eight mothers who were breast-feeding and taking sulphasalazine, analyses were done of mothers'serum, breast-milk and serum from their children. The results showed that the amount of sulphasalazine and sulphapyridine transferred to the child via the breast-milk is negligible with regard to the risk of kernicterus. It is concluded that a woman in need of sulphasalazine treatment can continue the medication throughout pregnancy and lactation without risk of development of kernicterus in her child. Only term infants without haemolytic disease were included in the study. Thus our conclusion is not necessarily valid for the prematurely born child or the child with haemolytic disease. 相似文献