全文获取类型
收费全文 | 46758篇 |
免费 | 3363篇 |
国内免费 | 2341篇 |
专业分类
耳鼻咽喉 | 1502篇 |
儿科学 | 409篇 |
妇产科学 | 172篇 |
基础医学 | 6043篇 |
口腔科学 | 1035篇 |
临床医学 | 4503篇 |
内科学 | 3350篇 |
皮肤病学 | 205篇 |
神经病学 | 8674篇 |
特种医学 | 1619篇 |
外国民族医学 | 3篇 |
外科学 | 10274篇 |
综合类 | 6922篇 |
现状与发展 | 1篇 |
预防医学 | 822篇 |
眼科学 | 2511篇 |
药学 | 2459篇 |
32篇 | |
中国医学 | 1317篇 |
肿瘤学 | 609篇 |
出版年
2024年 | 87篇 |
2023年 | 705篇 |
2022年 | 1031篇 |
2021年 | 1725篇 |
2020年 | 1787篇 |
2019年 | 1498篇 |
2018年 | 1420篇 |
2017年 | 1709篇 |
2016年 | 1716篇 |
2015年 | 1664篇 |
2014年 | 2882篇 |
2013年 | 2933篇 |
2012年 | 2384篇 |
2011年 | 2607篇 |
2010年 | 2289篇 |
2009年 | 2123篇 |
2008年 | 2251篇 |
2007年 | 2239篇 |
2006年 | 2052篇 |
2005年 | 1772篇 |
2004年 | 1640篇 |
2003年 | 1431篇 |
2002年 | 1245篇 |
2001年 | 1121篇 |
2000年 | 928篇 |
1999年 | 860篇 |
1998年 | 863篇 |
1997年 | 774篇 |
1996年 | 613篇 |
1995年 | 558篇 |
1994年 | 495篇 |
1993年 | 475篇 |
1992年 | 492篇 |
1991年 | 415篇 |
1990年 | 405篇 |
1989年 | 341篇 |
1988年 | 297篇 |
1987年 | 289篇 |
1986年 | 276篇 |
1985年 | 371篇 |
1984年 | 308篇 |
1983年 | 226篇 |
1982年 | 253篇 |
1981年 | 219篇 |
1980年 | 204篇 |
1979年 | 130篇 |
1978年 | 88篇 |
1977年 | 88篇 |
1976年 | 63篇 |
1975年 | 45篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Peter Marhofer Malachy Columb Phil M. Hopkins Manfred Greher Daniela Marhofer Max R. Levi Bienzle Markus Zeitlinger 《British journal of anaesthesia》2019,122(4):525-531
Background
The efficacy of dexamethasone in extending the duration of local anaesthetic block is uncertain. In a randomised controlled triple blind crossover study in volunteers, we tested the hypothesis that neither i.v. nor perineurally administered dexamethasone prolongs the sensory block achieved with ropivacaine.Methods
Ultrasound-guided ulnar nerve blocks (ropivacaine 0.75% wt/vol, 3 ml, with saline 1 ml with or without dexamethasone 4 mg) were performed on three occasions in 24 male volunteers along with an i.v. injection of saline 1 ml with or without dexamethasone 4 mg. The combinations of saline and dexamethasone were as follows: control group, perineural and i.v. saline; perineural group, perineural dexamethasone and i.v. saline; i.v. group, perineural saline and i.v. dexamethasone. Sensory block was measured using a VAS in response to pinprick testing. The duration of sensory block was the primary outcome and time to onset of sensory block the secondary outcome.Results
All 24 subjects completed the trial. The median [inter-quartile range (IQR)] duration of sensory block was 6.87 (5.85–7.62) h in the control group, 7.37 (5.78–7.93) h in the perineural group and 7.37 (6.10–7.97) h in the i.v. group (P=0.61). There was also no significant difference in block onset time between the three groups.Conclusion
Dexamethasone 4 mg has no clinically relevant effect on the duration of sensory block provided by ropivacaine applied to the ulnar nerve.Clinical trial registration
DRKS, 00014604; EudraCT, 2018-001221-98. 相似文献42.
Toni Kulju Joonas Haapasalo Ryan Verner Maxine Dibu‐Adjei Kai Lehtimki Sirpa Rainesalo Jukka Peltola 《Neuromodulation》2020,23(6):852-858
BackgroundIn vagal nerve stimulation (VNS) therapy, the release of VNS model 106 (AspireSR) allowed for responsive VNS (rVNS). rVNS utilizes a cardiac-based seizure detection algorithm to detect seizure-induced tachycardia to trigger additional stimulation. There are some studies suggesting clinical benefits of rVNS over traditional VNS, but the performance and significance of autostimulation mode in clinical practice are poorly understood.ObjectivesTo assess the effect of initiation of rVNS therapy and altered stimulation settings on the number of daily stimulations and energy consumption in VNS therapy and to compare autostimulation performance in different epilepsy types.Materials and MethodsRetrospective follow-up of 30 patients with drug-resistant epilepsy treated with rVNS including 17 new implantations and 13 battery replaces at a single center in Finland. Our data consist of 208 different stimulation periods, that is, episodes with defined stimulation settings and both autostimulation and total stimulation performance-related data along with clinical follow-up.ResultsThe variation in autostimulation frequency was highly dependent on the duration of the OFF-time and autostimulation threshold (p < 0.05). There was a large additional effect of autostimulation mode on therapy time and energy consumption with longer OFF-times, but a minor effect with shorter OFF-times. Significantly more autostimulations were triggered in the temporal lobe and multifocal epilepsies than in extratemporal lobe epilepsies.ConclusionsThe initiation of autostimulation mode in VNS therapy increased the total number of stimulations. Shortening the OFF-time leads to a decreased number and share of automatic activations. Epilepsy type may affect autostimulation activity. 相似文献
43.
44.
45.
《Revista espa?ola de anestesiología y reanimación》2022,69(8):502-505
Effective management and control of peri- and postoperative pain in hip surgery is essential in order to minimize the use of opioids and their adverse effects. Effective regional analgesia for hip pain is made particularly challenging by the complex innervation of the hip joint. Standard regional techniques can be associated with complications, including incomplete anesthesia, hypotension, or lower limb weakness. We present the case of a 5-year-old girl with a history of infantile cerebral palsy who underwent bilateral varus derotation osteotomy and adductor tenotomy due to paralytic dislocation. She received bilateral PENG block and femoral cutaneous nerve block - a simple technique that covers all the nerves involved in the sensory innervation of the joint capsule without the need for multiple injections. 相似文献
46.
We describe a case of undiagnosed heart block which was detected during the postpartum surgical repair of a vaginal tear, and the subsequent investigations that confirmed diagnosis of atrio-ventricular heart block. 相似文献
47.
目的探讨腮腺切除术中应用沿面神经总干顺行解剖面神经的治疗效果及安全性。方法选取我院2016年2月至2019年3月收治的60例择期行腮腺切除术的患者,随机分为观察组与对照组各30例。对照组沿面神经总干逆行解剖面神经,观察组沿面神经总干顺行解剖面神经,观察两组患者术后1个月面神经功能及术后并发症发生情况。结果术后1个月,两组患者的面神经功能分级比较无统计学差异(P>0.05);观察组的术后并发症发生率为10.00%,明显低于对照组的33.33%(P <0.05)。结论临床行腮腺切除术中,沿面神经总干顺行解剖面神经可降低术后并发症发生率,值得推广。 相似文献
48.
49.
50.