全文获取类型
收费全文 | 28284篇 |
免费 | 3666篇 |
国内免费 | 378篇 |
专业分类
耳鼻咽喉 | 186篇 |
儿科学 | 350篇 |
妇产科学 | 402篇 |
基础医学 | 1861篇 |
口腔科学 | 854篇 |
临床医学 | 6857篇 |
内科学 | 2752篇 |
皮肤病学 | 275篇 |
神经病学 | 1059篇 |
特种医学 | 423篇 |
外国民族医学 | 7篇 |
外科学 | 2833篇 |
综合类 | 3533篇 |
现状与发展 | 2篇 |
一般理论 | 15篇 |
预防医学 | 5065篇 |
眼科学 | 161篇 |
药学 | 2654篇 |
41篇 | |
中国医学 | 1615篇 |
肿瘤学 | 1383篇 |
出版年
2024年 | 95篇 |
2023年 | 755篇 |
2022年 | 665篇 |
2021年 | 1432篇 |
2020年 | 1655篇 |
2019年 | 1656篇 |
2018年 | 1488篇 |
2017年 | 1397篇 |
2016年 | 1251篇 |
2015年 | 1306篇 |
2014年 | 2025篇 |
2013年 | 2272篇 |
2012年 | 1737篇 |
2011年 | 1830篇 |
2010年 | 1554篇 |
2009年 | 1420篇 |
2008年 | 1367篇 |
2007年 | 1301篇 |
2006年 | 1061篇 |
2005年 | 925篇 |
2004年 | 768篇 |
2003年 | 682篇 |
2002年 | 532篇 |
2001年 | 437篇 |
2000年 | 394篇 |
1999年 | 351篇 |
1998年 | 288篇 |
1997年 | 201篇 |
1996年 | 197篇 |
1995年 | 166篇 |
1994年 | 157篇 |
1993年 | 144篇 |
1992年 | 106篇 |
1991年 | 113篇 |
1990年 | 75篇 |
1989年 | 60篇 |
1988年 | 65篇 |
1987年 | 63篇 |
1986年 | 47篇 |
1985年 | 46篇 |
1984年 | 40篇 |
1983年 | 22篇 |
1982年 | 38篇 |
1981年 | 19篇 |
1980年 | 26篇 |
1979年 | 32篇 |
1978年 | 19篇 |
1977年 | 16篇 |
1976年 | 15篇 |
1974年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
41.
42.
慢性疼痛涉及临床各科的多种疾病,包括一些重大疾病和疑难疾病。中医体质学是中医学的新兴学科,其体质分类、体病相关思想以及“辨体论治”的诊疗方法已广泛应用到临床各科疾病的诊疗中。文章探讨了以中医体质学思想指导疼痛性疾病诊疗的若干理论问题,认为疼痛性疾病的发生与患者体质类型存在密切的关系。因此,在临床辨治疼痛性疾病时要考虑患者体质因素。所施方药不仅要符合病证特点,也要针对患者体质类型。并列举国医大师王琦教授辨体论治慢性前列腺炎盆腔疼痛综合征、偏头痛、过敏性头痛等疼痛性疾病的案例加以分析,以期为相关领域同仁提供参考。 相似文献
43.
Recognizing and managing a deteriorating patient: a randomized controlled trial investigating the effectiveness of clinical simulation in improving clinical performance in undergraduate nursing students 下载免费PDF全文
44.
Stuart J. Dilley Tracey J. Weiland Robert O’Brien Neil J. Cunningham Julian E. Van Dijk Rosie M. Mahoney 《Teaching and learning in medicine》2015,27(1):71-79
Theory: Immersive simulation is a common mode of education for medical students. Observation of clinical simulations prior to participation is believed to be beneficial, though this is often a passive process. Active observation may be more beneficial. Hypotheses: The hypothesis tested in this study was that the active use of a simple checklist during observation of an immersive simulation would result in better participant performance in a subsequent scenario compared with passive observation alone. Methods: Medical students were randomized to either passive or active (with checklist) observation of an immersive simulation involving cardiac arrest prior to participating in their own simulation. Performance measures included time to cardiopulmonary resuscitation (CPR) and time to defibrillation and were compared between first and second scenarios as well as between passive and active observers. Results: Seventy-nine simulations involving 232 students were conducted. Mean time to CPR was 18 seconds (SD = 11.6) for those using the checklist and 24 seconds (SD = 15.8) for those who observed passively (M difference = 6 seconds), t(35) = 1.46, p =.153. Time to defibrillation was 94 seconds (SD = 26.4) for those using the checklist and 92 seconds (SD = 23.8) for those who observed passively (M difference = –2 seconds), t(38) =.21, p =.837. Time to CPR was 24 seconds (SD = 15.8) for passive observers and 31 seconds (SD = 21.0; M difference = 7 seconds), t(35) = 1.13, p =.265, for their first scenario counterparts. Time to CPR was 18 seconds (SD = 11.6) for active observers and 36 seconds (SD = 26.2; M difference = 18 seconds), t(24) = 2.81, p =.010, for their first scenario counterparts. Time to defibrillation was 92 seconds (SD = 23.8) for passive observers and 125 seconds (SD = 32.2; M difference = 33 seconds), t(33) = 3.63, p =.001, for their first scenario counterparts. Time to defibrillation was 94 seconds (SD = 26.4) for the active observers and 132 seconds (SD = 52.9; M difference = 38 seconds), t(28) =.46, p =.008, for their first scenario counterparts. Conclusions: Observation alone leads to improved performance in the management of a simulated cardiac arrest. The active use of a simple skills-based checklist during observation did not appear to improve performance over passive observation alone. 相似文献
45.
46.
47.
《Journal of pharmaceutical sciences》2019,108(10):3425-3433
This study aimed at evaluating how encapsulation in a regular nanocarrier (NC) (providing extended circulation time) or in a brain-targeting NC (providing prolonged circulation time and increased brain uptake) may influence the therapeutic index compared with the unformulated drug and to explore the key parameters affecting therapeutic performance using a model-based approach. Pharmacokinetic (PK) models were built with chosen PK parameters. For a scenario where central effect depends on area under the unbound brain concentration curve and peripheral toxicity relates to peak unbound plasma concentration, dose-effect and drug-side effect curves were constructed, and the therapeutic index was evaluated. Regular NC improved the therapeutic index compared with the unformulated drug due to reduced peripheral toxicity, while brain-targeting NC enhanced the therapeutic index by lowering peripheral toxicity and increasing central effect. Decreasing drug release rate or systemic clearance of NC with drug still encapsulated could increase the therapeutic index. Also, a drug with shorter half-life would therapeutically benefit more from a NC encapsulation. This work provides insights into how a NC for brain delivery should be optimized to maximize the therapeutic performance and is helpful to predict if and to what extent a drug with certain PK properties would obtain therapeutic benefit from nanoencapsulation. 相似文献
48.
Saisanjana Kalagara Adam E.M. Eltorai J. Mason DePasse Alan H. Daniels 《The spine journal》2019,19(1):182-185
BACKGROUND
Online physician rating websites are increasingly used by patients to evaluate their doctors. The purpose of this investigation was to evaluate factors associated with better spine surgeon ratings.METHODS
Orthopedic spine surgeons were randomly selected from the North American Spine Society directory utilizing a random number generator. Surgeon profiles on three physician rating websites, namely, www.HealthGrades.com, www.Vitals.com, and www.RateMDs.com, were analyzed to gather qualitative and quantitative data on patients’ perceptions of the surgeons. Independent variables from the websites were analyzed in relation to overall physician or patient satisfaction rating. Comments were coded by subject into following three categories: professional competence, bedside manner, and practice characteristics.RESULTS
A total of 250 surgeons were evaluated, and 92% (n=230) of these doctors had at least one rating among the three websites. The surgeons with a higher average rating had significantly better trust (p<.01), scheduling (p<.01), staff (p<.01), helpfulness (p<.01), and punctuality (p<.01) scores but significantly less experience (p<.05). A linear regression model for the average rating of each surgeon (R2 value=0.754) yielded only following three significant variables: trustworthiness (p<.01), experience match (p<.05), and the average number of negative comments on surgeon's professional competence (p<.05). Trustworthiness (β=0.749) was the strongest predictor variable of physician rating, followed by the number of negative professional competence comments (β=?0.132) and experience match (β=?0.112).CONCLUSIONS
This investigation assessed spine surgeon online patient ratings and categorized factors that patients associate with quality care. Trustworthiness was the most significant predictor of positive ratings, whereas ease of scheduling, quality of staff, helpfulness, and punctuality were also associated with higher patient ratings. Understanding what patients value may help optimize care of spine surgery patients. 相似文献49.
目的研究在肝癌介入术治疗患者中应用心理护理干预的临床价值。方法本文数据计算目标是2018年1月-2019年6月的60例肝癌介入术治疗患者,以随机数字表法的形式进行分组研究,常规组(n=30)开展一般护理干预,心理组(n=30)开展心理护理干预,比较心理组与常规组肝癌介入术治疗患者临床护理情况。结果心理组肝癌介入术治疗患者治疗后临床护理满意度、焦虑评分、抑郁评分与常规组比较,两组治疗后肝癌介入术治疗患者焦虑评分、抑郁评分与治疗前比较,P<0.05,差异有统计学意义。结论将心理护理干预应用在肝癌介入术治疗患者中可提升护理满意度。 相似文献
50.
AbstractThis article follows up a pilot project to help educate local nurses and patient educators on freely available consumer health resources. The Outreach Coordinator and Clinical Librarian at an academic medical center created a one-hour in-person and online class with continuing education credit and an online guide. Nurses frequently act as patient educators at the bedside and are therefore an important target for consumer health education. While nurses in an urban setting may have more access to educational opportunities, these opportunities are needed even more in rural settings. Librarians can obtain funding to travel and teach classes at rural community hospitals. 相似文献