The effect of 6 months or longer duration of chronic obstructive respiratory disease medication on the oral health parameters of adults

The objectives of this study were to study the effect of COPD medication of 6 months or more duration on oral health parameters of adult patients. A cross‐sectional study was conducted to assess and compare the decayed, missing, and filled teeth (DMFT), oral hygiene index‐simplified (OHI‐S), periodontal disease index (PDI) scores, and presence of candida (colony‐forming units [CFU]) among adult patients aged 20–45 years who had a history of 6 months or longer duration usage of chronic respiratory disease medications, with controls. A total of 170 participants each were taken in both the groups. Oral health parameters like DMFT scores (p ≤ 0.002), OHI‐S (p ≤ 0.001), calculus scores (p ≤ 0.001), plaque scores (p ≤ 0.001), and CFU/ml of candida species (p ≤ 0.001) were higher among cases than controls. DMFT scores and candida presence were significantly higher among those whose treatment duration was greater than 5 years as compared to those with lesser duration. Gingival‐periodontal component scores of PDI were lower among cases than controls (p ≤ 0.001). Our findings suggest the need for regular oral health maintenance for those under COPD treatment and for greater research into the possible protective role of inhaled corticosteroids in limiting periodontal disease among patients.     

产前认知辅导对初产妇分娩方式及产程时间的影响

目的探讨产前认知辅导对初产妇分娩方式及产程时间的影响。方法选取2016年1~12月间我院妇产科收治的初产妇80例,依据随机数字表法分为产前常规检查组(n=40)和产前认知辅导组(n=40)。对两组初产妇的分娩方式、配合分娩情况及自然分娩初产妇的各阶段产程时间进行统计分析。结果产前认知辅导组初产妇的自然分娩率为75.0%(30/40)显著高于产前常规检查组52.5%(21/40)(P0.05),剖宫产率、社会因素剖宫产率、难产率分别为22.5%(9/40)、5.0%(2/40)、22.5%(9/40)均显著低于产前常规检查组42.5%(17/40)、25.0%(10/40)、45.0%(18/40)(P0.05),配合好比例[72.5%(29/40)]显著高于产前常规检查组[35.0%(14/40)](P0.05),配合一般、配合差比例[22.5%(9/40)、5.0%(2/40)]均显著低于产前常规检查组[42.5%(17/40)、22.5%(9/40)](P0.05),自然分娩初产妇的第二产程、总产程时间均显著短于产前常规检查组(P0.05)。结论产前认知辅导能够有效提升初产妇的自然分娩率,降低初产妇的剖宫产率,并缩短自然分娩初产妇的产程时间。     

The microbiome and atopic eczema: More than skin deep

Discoveries in the defective molecular composition of the epidermal barrier, such as the epidermal protein filaggrin, in those with atopic eczema (or atopic dermatitis [AD]) have proved crucial in understanding this disease, but its aetiology remains to be fully elucidated. The epidermal barrier is just one interface between the microbial world and our immune system. Recent advances in molecular technology have demonstrated for the first time the true scale of the normal human microbiome and changes seen in disease states. In this review article we discuss the role of the human microbiome in the aetiology and maintenance of AD. The role of Staphylococcus aureus within the skin microbiome is examined, in addition to the role of other bacteria and fungi, identified using novel culture‐independent methods. The significant contribution of the gut microbiome and its manipulation via probiotic use is also reviewed. We emphasise that the microbiome of separate systems, including the gut, has a significant role to play in the manifestation of this cutaneous disorder. To date, there has been a lack of studies investigating whether changes to the lung microbiome may play a role in AD. An early interaction between the microbiome and immune system via multiple routes (skin–gut–lung) could feasibly affect the risk of a subsequent development of atopic diseases. When making management decisions for AD patients, clinicians must be mindful of the role of the microbiome.     

2~6岁儿童牙科诊室行为影响因素研究

目的探寻2~6岁儿童牙科诊室行为的影响因素,建立简便易行的低龄儿童牙科诊室行为预测模型。方法对96例接受牙科治疗的2~6岁儿童的牙科诊室行为评估分为配合组与不配合组;问卷调查获取家长口腔健康意识、母亲牙科焦虑、儿童日常行为特点及情绪类型等资料;使用SPSS11.5软件分析组间各因素差异及与牙科诊室行为的相关程度。结果两组患儿年龄(4.35±0.83 vs 3.85±1.07)和情绪应激性(17.77±4.88 vs 23.23±4.76)之间差异有统计学意义(P0.05);治疗持续时间、幼儿园入园表现、家长对儿童口腔疾患的责任承担度与儿童口腔诊室行为均存在显著相关性(P0.05)。结论通过治疗前与家长的针对性沟通可有效预测低龄儿童牙科诊室行为。     

Effect of oil pulling in promoting oro dental hygiene: A systematic review of randomized clinical trials

AimTo critically appraise and evaluate the evidence from randomized clinical trials (RCTs) examining the effectiveness of oil pulling on oro dental hygiene.MethodsWe conducted electronic searches in Medline, Embase, Amed, The Cochrane Library and Cinahl databases from inception to February 2015, and assessed reporting quality using the Cochrane risk of bias criteria. We included RCTs that compared oil pulling using conventional cooking oils with a control intervention. Our primary outcomes were measures of oro dental hygiene using validated scales.ResultsElectronic searches yielded 26 eligible studies, of which five RCTs comprising a total of 160 participants were included. The studies varied in reporting quality, lasted between 10 and 45 days, and compared oil pulling with chlorhexidine, placebo or routine dental hygiene practice. Three studies reported no significant differences in post intervention plaque index scores between oil pulling and control groups (Chlorhexidine mouthwash +/− Placebo): p = 0.28, 0.94, and 0.38, respectively. Two studies reported no significant difference in post-intervention modified gingival index score between oil pulling and Chlorhexidine mouthwash groups (p = 0.32 and 0.64).ConclusionThe limited evidence to date from clinical trials suggests that oil pulling may have beneficial effects on oro dental hygiene as seen for the short period of time investigated. Given that this is a potentially cost-effective intervention, this practice might be of particular benefit. Future clinical trials should be more rigorous and better reported.