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81.
Laryngeal Transplantation in 2005: A Review 总被引:3,自引:0,他引:3
M. A. Birchall R. R. Lorenz G. S. Berke E. M. Genden B. H. Haughey M. Siemionow M. Strome 《American journal of transplantation》2006,6(1):20-26
There is no good surgical, medical or prosthetic solution to the problems faced by those with a larynx whose function is irreversibly damaged by tumor or trauma. Over the past 10 years, the pace of research designed to establish laryngeal transplantation as a therapeutic option for these persons has increased steadily. The biggest milestone in this field was the world's first true laryngeal transplant performed in Cleveland, Ohio in 1998. The recipient's graft continues to function well, in many respects, even after 7 years. However, it has also highlighted the remaining barriers to full-scale clinical trials. Stimulated by these observations, several groups have accumulated data which point to answers to some of the outstanding questions surrounding functional reinnervation and immunomodulation. This review seeks to outline the progress achieved in this field by 2005 and to point the way forward for laryngeal transplantation research in the 21st century. 相似文献
82.
S.L. CHARLES NGU PETER DUVAL CATHRYN COLLINS 《Journal of Medical Imaging and Radiation Oncology》1992,36(4):321-322
Management of breast cancer during pregnancy is complicated by the high risks of abortion and foetal malformation from the use of radio therapy and chemotherapy. A case of breast cancer during pregnancy, treated with radiotherapy, and the estimated foetal dose is reported. 相似文献
83.
本文报告260例恶性肿瘤患者血清维生素A、E、C水平的测定结果。发现除慢性白血病外,蓁7种恶性肿瘤患者血清维生素A水平平均显著低于健康人(P<0.01);急性白血,肝癌、食管癌患者血清维生素E水平显著低于健康人(P<0.05);急性粒细胞白血病、急性单核细胞白血病、肝癌患者血维生素C水平显著低于健康人(P<0.01)。本研究工作为维生素A、E、C药物在肿瘤临床上的应用提供了参考。 相似文献
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F. A. Calvo O. Abuchaibe I. Azinovic E. Tangco J. Aristu R. Martínez F. Pardo J. Alvarez-Cienfuegos J. M. Berián 《European radiology》1992,2(1):29-34
Thirty patients with malignant tumours in the upper abdomen underwent surgery and intraoperalive radiation (IORT), using electron beam, to: the surgical bed, residual or unresected tumour. The technical aspects and results of this treatment are described. Renal, adrenal, bile duct and gastrointestinal tumours were treated. along with several other lesions. The surgical procedure consisted in 10 cases simply of exposure of the tumour for IORT and in 20 the tumour was resected. The TORT dose ranged from 10 to: 20 Gv. In 13 patients, external beam radiation was also given to: residual tumour or to: areas of high risk for recurrence. Chemotherapy was given to: 10 patients. Tolerance to: the combined treatment was acceptable; with few complications related to: IORT.The median follow-up and survival time 23 months (range 4-more than 70 months). Local tumour control rate (or tumour stabilisation) is 90%. Distant metastases developed in 19 patients (63%). The actuarial survival rate for the group projected at 70 months (maximum follow-up) is 37%. IORT in useful in the management of tumours arising in the upper abdominal organs, for palliation surgery or when resectability of the tumour is in doubt. Indications for IORT include patients with uncommon tumours of the upper abdomen who are not be candidates for standardised cancer treatment.Presented at the European Congress of Radiology, Vienna, September 15–20,1991 相似文献
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本文对上消化道肿瘤高发区经初筛的120例高危人群粘膜组织做了流式细胞DNA含量、内窥镜和组织病理学检查的对比研究。其结果显示的肿瘤阳性检出率分别为27.5%、6.7%和14.0%。对内窥镜诊断为不同胃疾病患者的流式细胞术分析发现,流式细胞术阳性检出率,胃癌组为75.0%,萎缩性胃炎组为28.3%,浅表性胃炎组为7.1%,正常粘膜组为0%。DI值均值,炎症组(萎缩性胃炎和浅表性胃炎)患者与正常对照组接近,而癌组则明显升高。增殖指数和S期细胞比例,从正常对照→浅表性胃炎→萎缩性胃炎→胃癌组,呈递增变化,而且各组间有显著差异。 相似文献
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Y Miyamoto M Nakatani M Ida T Ishikawa N Okazawa M Ariizumi F Tsujimoto K Mizunuma Y Fukuda S Tada 《Journal of clinical ultrasound : JCU》1989,17(5):309-318
Ultrasonography was performed in 45 cases of gastric cancer. Specimens from all 45 cases of gastric cancer were subjects to ultrasonographic study by the water immersion method for comparison with histology. In 32 of these 45 cases in vivo ultrasonographic evaluation was performed prospectively. The overall accuracy rates for the diagnosis of the depth of cancerous invasion were almost 80% in both in vitro and in vivo studies. In vivo ultrasonographic findings agreed well with those from the specimen studies. Ultrasonography was considered to be useful in the diagnosis of gastric malignancies. 相似文献
90.
目的:检测荷瘤鼠乳腺癌组织的双光子荧光光谱。方法:乳腺癌荷瘤鼠腹腔注射血卟啉(HpD)。以飞秒激光照射小鼠的癌组织部位及周围正常组织部位。观察HpD双光子荧光光谱。结果:小鼠的癌组织部位可观察到外源性HpD双光子荧光光谱,而正常组织部位未观察到明显的双光子荧光光谱。结论:结论:飞秒激光外源性血卟啉双光子荧光诊断可作为癌症诊断的新方法。 相似文献