[Translated article] Immediate-Onset Linear Effluvium Associated With High-Density Hair Transplantation: A Series of 28 Case

We describe 28 patients who experienced effluvium with previously unreported features shortly after hair transplant surgery. Notable features were as follows: (a) a linear morphology; (b) immediate onset (1–3 days); (c) association with dense-pack grafting in areas of receding hairline at the temples (Mickey Mouse pattern); (d) a progressive increase in the diameter of the hair loss line (wave-like pattern); (e) in some cases, subsequent concentric linear effluvium on the crown (donut pattern); and (f) other forms of previously unreported immediate-onset effluvium. The linear morphology could be the result of dense packing, which can cause perilesional hypoxia and loss of miniaturized hairs around the recipient area. Since linear hair loss can cause patient concern about graft failure, we recommend taking images of transplanted and nontransplanted areas immediately after surgery and warning patients in advance about these transient effects, which are fully reversed in 3 months.     

[Translated article] Histopathologic and Trichoscopic Correlations in Nonscarring Alopecias

Trichoscopy is an essential tool in the evaluation of alopecia. The current compilation of trichoscopic signs in this setting helps distinguish between different forms of hair loss and has improved our understanding of the pathogenic mechanisms involved. The trichoscopic signs are always linked to the pathogenic mechanisms of the alopecia being examined. We examine correlations between the main trichoscopic and histopathologic findings in nonscarring alopecias.     

微针联合米诺地尔治疗脱发的临床效果

目的 探讨微针联合米诺地尔治疗脱发的临床效果。方法 选取我院2022年4月-7月收治的44例 脱发患者作为对照组，另选取我院2022年8月-12月收治的44例脱发患者作为研究组。对照组接受米诺 地尔治疗，研究组接受微针联合米诺地尔治疗，比较两组临床疗效、毛发密度与直径及并发症发生情 况。结果 研究组治疗总有效率（97.73%）高于对照组（86.36%），差异有统计学意义（P ＜0.05）；两组治 疗后毛发密度与直径大于治疗前，且研究组大于对照组，差异有统计学意义（P＜0.05）；研究组并发症率 发生率（2.27%）低于对照组（13.64%），差异有统计学意义（P ＜0.05）。结论 微针联合米诺地尔治疗脱 发的临床效果较为确切，可以增大毛发密度和直径，且并发症发生率低。     

[Translated article] Trichoscopy: An Update

Trichoscopy is a simple, noninvasive office procedure that can be performed using a handheld or digital dermatoscope. This tool has gained popularity in recent years, because it provides useful diagnostic information for hair loss and scalp disorders by enabling the visualization and identification of distinctive signs and structures. We present an updated review of the trichoscopic features described for some of the most common hair loss disorders seen in clinical practice. Dermatologists should be familiar with these helpful features, as they can significantly aid the diagnosis and follow-up of numerous conditions, such as alopecia areata, trichotillomania, and frontal fibrosing alopecia.     

雄激素性秃发病人血液流变学指标与血清雄激素水平的关系分析

目的探讨雄激素性秃发病人血液流变学指标与血清雄激素水平的关系。方法选取 2019年 6月至 2021年 6月在四川大学华西医院门诊就诊的 98例雄激素性秃发病人为观察组，另选取 100例健康体检者作为对照组，检测并对比两组的血液流变学指标(包括全血高切、全血中切、全血低切、血浆黏度、血沉、红细胞压积)及血清雄激素水平［包括血清睾丸酮(T)、脱氢异雄酮(DHEA)和双氢睾酮(DHT)］的水平。给予观察组相关治疗，检测并对比治疗前后病人的血液流变学指标。采用 Pearson法分析雄激素性秃发病人血液流变学指标与血清雄激素水平的关系。结果对照组中有 5例主动撤回知情同意书，观察组中无脱落 /剔除病例，最终共纳入对照组 95例健康体检者和观察组 98例雄激素性秃发病人；观察组全血高、中、低切及红细胞压积均高于对照［(5.65±0.89)比(3.55±0.57)mPa·s，(7.89±1.04)(4.85±0.71)mPa·s，(13.35±2.56)(6.12±1.23)mPa·s，(0.57±0.09)%比(0.45±0.05)%P<0.05］；观察组和对照组男性病人 T、 及 DHT水平均高于女性病人［察组( 574.12±114.21)比( 75.23±15.04)ng/ dL，(5.35±0.67)比( 4.02±0.71)μg/L，(194.35±35.78)比( 110.25±20.12)ng/L；对照组( 456.45±90.21)比( 45.36±9.03)ng/dL，(4.13±DHEA比观比0.54)比(2.54±0.45)μg/L，(104.78±25.15)比( 68.45±13.78)ng/L，P<0.05］；且观察组男性和女性病人的 T、DHEA及 DHT水平均高于与对照组男性和女性病人( P<0.05)；观察组治疗后的全血高切、全血中切、全血低切及红细胞压积均较治疗前降低(P<0.05)； Pearson相关性分析发现，雄激素性秃发男性和女性病人全血高切、全血中切、全血低切及红细胞压积与 T、DHEA及 DHT水平均呈正相关(P<0.05)。结论雄激素性秃发病人血清雄激素水平和血液流变学指标均高于健康人群，且其血液流变学指标与血清雄激素水平呈正相关，提示监测雄激素性秃发病人血液流变学变化对临床诊治具有一定的指导意义。