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101.
1153例重度心力衰竭者,左心室射血分数均小于0.30,心功能为纽约心脏协会Ⅲ~Ⅳ级,病因包括缺血和非缺血性。随机分为接受他汀类药物的治疗组134例(12%),或未用药对照组(88%)。人均随访1.3年,观察两组病死率的差异。结果,随访期内两组共有413例不幸死亡(29%/年)。校正年龄、性别 相似文献
102.
<正>新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopa-thy,HIE)是因围产期缺氧和缺血,导致胎儿和新生儿脑损伤,临床上出现一系列脑病后遗症。我们将药物联合抚触治疗中 相似文献
103.
李宏建 《国际脑血管病杂志》2006,14(6):440-440
有症状颅内动脉粥样硬化血栓形成性狭窄(intracranial atherothrombotic stenoses,ICAS)与缺血性脑血管事件的高发率有关。 相似文献
104.
一、全球高血压和心血管疾病的负担与挑战
高血压在人群中广泛流行,当今全球高血压患病率为25%,预计到2025年,可升至60%。高血压是导致心血管疾病(包括缺血性心脏病或冠心病、脑血管病或卒中、周围动脉疾病、和心脏衰竭等)发生和死亡的最重要危险因素, 相似文献
105.
盐酸法舒地尔治疗缺血性心肌病心力衰竭 总被引:6,自引:0,他引:6
袁洪文 《现代中西医结合杂志》2009,18(6)
目的用6 min步行试验和多普勒超声心动图评价盐酸法舒地尔治疗缺血性心肌病心力衰竭的疗效。方法将60例因缺血性心肌病而导致慢性心力衰竭的患者分为2组各30例,均采用常规治疗,治疗组同时行静脉滴注盐酸法舒地尔60 mg每日1次。评估2组治疗前后6 min步行距离、左心室收缩末期内径(LVESD)、左心室收缩末期容积(LDESV)、左心室射血分数(LVEF)情况。结果用药3个月后治疗组6 min步行距离、LVESD、LVESV、VLEF较对照组均明显改善(P均<0.05)。结论在常规治疗基础上加用盐酸法舒地尔可提高运动耐量,改善患者心脏收缩功能,且耐受性良好。 相似文献
106.
Yulu Miao Mingxia Zhang Yulin Nie Wan Zhao Bin Huang Zhengming Jiang Shaoxiong Yu Zhibin Huang Hongjin Fu 《中国神经再生研究》2007,2(2):126-128
BACKGROUND: Besides local changes of cranial parenchymal cells, hemorrhage, etc., severe traumatic brain injuries also cause the changes of total body fluid and various functions, and the changes of lymphocytes and T lymphocyte subsets should be paid more attention to. OBJECTIVE: To reveal the changing laws of T lymphocyte subsets after severe traumatic brain injury, and compare with mild to moderate brain injury. DESIGN: A comparative observation. SETTINGS: Department of Neurosurgery, Longgang District Buji People's Hospital of Shenzhen City; Central Laboratory of Shenzhen Hospital of Prevention and Cure for Chronic Disease. PARTICIPANTS: All the subjects were selected from the Department of Neurosurgery, Longgang District Buji People's Hospital of Shenzhen City from August 2002 to August 2005. Thirty patients with severe brain injury, whose Glasgow coma score (GCS) was ≤ 8 points, were taken as the experimental group, including 21 males and 9 females, aging 16 - 62 years. Meanwhile, 30 patients with mild traumatic brain injury were taken as the control group (GCS ranged 14- 15 points), including 18 males and 12 females, aging 15 -58 years. All the subjects were in admission at 6 hours after injury, without disease of major organs before injury Informed consents were obtained from all the patients or their relatives. METHODS: (1) The T lymphocytes and the subsets in peripheral blood were detected with immunofluorescent tricolor flow cytometry at l, 3, 7 and 14 days after injury in both groups. (2) The conditions of pulmonary infections were observed at 4 days after injury. The differences of measurement data were compared with the t test. MAIN OUTCOME MEASURES: Changes of T lymphocytes subsets at 1 - 14 days after severe and mild or moderate traumatic injury. RESULTS: Finally, 28 and 25 patients with mild to moderate traumatic brain injury, whereas 25 and 21 patients with severe traumatic brain injury were analyzed at 7 and 14 days respectively, and the missed ones died due to the development of disease. (1) Changes of T lymphocyte subsets: At 1 and 3 days after injury, CD3, CD4, CD8, CD4/CD8 began to decrease, whereas CD8 increased in the experimental group, which were very significantly different from those in the control group (t =2.77 - 3.26, P 〈 0.01), and began to recover at 7 days, which were significantly different from those in the control group (t = 2.06 - 2.24, P 〈 0.05), and generally recovered to the normal levels at 14 days (P 〉 0.05). (2) Conditions of pulmonary infections: At 4 days after injury, the rate of pulmonary infection was significantly different between the experimental group and control group [73% (22/30), 0, x2=37.29, P 〈 0.01]. CONCLUSION: Patients with severe traumatic brain injury suffer from damages of cellular immune function at early period (within 7 days), and they are easily to be accompanied by pulmonary infections. 相似文献
107.
方宁静 《中国实用神经疾病杂志》2007,10(9):75-76
颈动脉粥样硬化是缺血性脑卒中的最重要病因和危险因素.为探讨颈动脉粥样硬化和缺血性卒中的关系,我们通过对72例经CT、MRI确诊的缺血性卒中患者颈动脉彩色多普勒超声检查作回顾性分析. 相似文献
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