特发性突聋的疗效分析

目的了解影响特发性突聋临床疗效的有关因素。方法对50例(52耳)不同性别、年龄、病程、听力损害程度及眩晕的有无5个方面特发性突聋的临床资料进行综合回顾性分析。结果性别的差异、年龄的大小、病程的长短对疗效差异的影响并不显，但是听力损失的程度和眩晕(两均是P＜0．005)则有统计学意义。结论听力损失的程度和眩晕是影响特发性突聋疗效的肯定因素。     

神经生长因子基因转染联合强化铁营养防治豚鼠爆震性聋的实验研究

Objective To study the protective effects of adenovirus-mediated human beta-nerve growth factor gene (hNGFβ) transfer combined with iron fortified nutrition on blast hearing damage in guinea pigs. Methods Deafness was induced by blast (172dB SPL) in 35 healthy guinea pigs. Seven days after noise exposure, 10 guinea pigs were inoculated with adenovirus-mediated hNGFβ (Ad-hNGFβ) into the perilymphatic space (the gene group), another 10 guinea pigs were given hNGFβ combined with iron fortified nutritional diet (the combination group), still another 10 guinea pigs were inoculated with artificial perilymphatic fluid (APF), and 5 guinea pigs served as control, given neither medicine nor noise exposure. Auditory brainstem response (ABR) threshold shifts were monitored in the guinea pigs before blast exposure and after gene transfer. Changes in cochlear morphology were examined with immunohistochemical and HE staining. Results One week after successful inoculation of hNGFβ, it was noted that Ad-hNGFβ protein was expressed in each turn of the cochlea, and its intensity was almost equal. After gene transfer in the combination group and the gene group, ABR threshold shifts at week 1 and 4 were significantly smaller than those of the APF group. HE staining showed that the number of the spiral ganglion cells in the combination group and the Ad-hNGFβ group was significantly higher than that of the control group after 4 weeks (P<0.01). Conclusions Ad-hNGFβ combined with iron fortified nutritional diet was effective in the prevention and treatment of blast hearing damage of cochlear hair cells.     

突发性、群体性细菌性痢疾的抢救及护理40例

夏季是肠道传染病的好发季节,细菌性痢疾是痢疾杆菌引起的常见急性肠道传染病.主要借染菌的食物、饮水和手等经口感染[1].2003年6月上旬,我县某小学近百名小学生因食用被粪便污染的生井水而突发群体性细菌性痢疾.我院在6月6～7日集中收治了40例细菌性痢疾的患儿,在院部、护理部组织管理、全院通力合作下,患儿得到了及时有效的治疗与护理,全部治愈出院,现报告如下.     

血栓通联合β-七叶皂甙钠治疗突发性耳聋的疗效观察

目的：观察血栓通联合β-七叶皂甙钠治疗突发性耳聋的临床疗效。方法：30例患者静脉滴注血栓通和β-七叶皂甙钠，14天为1疗程。治疗前后检查电测听和血液流变学指标。结果：30例患者治疗后平均听力提高40dB，总有效率93．3％，血液流变学指标显著改善。结论：血栓通联合β-七叶皂甙钠能有效治疗突发性耳聋。     

中西医结合治疗突发性耳聋的疗效观察

突发性耳聋（突聋）是指突然发生的原因不明的感觉神经听力损失，通常为单耳发病，极少为双耳，可伴有耳鸣，眩晕等。我院应用中西医药物结合治疗３６例（３８耳）突聋，现报告如下。１临床资料１．１一般资料：凡拟诊为突聋者，均经临床纯音测听，眼震电图，电导纳检查，...     

健康教育在治疗突发性聋疗效中的作用

突发性聋简称暴聋，是指几小时内突然发生原因不明的一种感音神经性耳聋，为耳鼻喉科常见急症。该病的发病率呈上升趋势，发病年龄呈年轻化趋势。本文通过对58例突发性聋患者进行心理、行为治疗以及饮食指导等全过程进行健康教育，使患者的自信心和社会参与能力得到了明显的提高，收到了良好的效果。     

中西医结合治疗突发性耳聋的疗效观察

突发性耳聋是耳鼻咽喉科的常见病、多发病。其发病急骤，严重危害人类的健康，然其确切病因及发病机理尚不完全明了，近年来复方钊剂对突发性耳聋的治疗其疗效已成为大多数学者认可。我科自2003～2005年期间采用中西医结合治疗突发性耳聋72例，取得较好的疗效，报道如下。     

用高压氧和药补救治疗突发性耳聋5例报告

目的:突发性耳聋病程超过1个月,探讨应用高压氧给予补救治疗的疗效和价值。方法:肌肉注射654-2后,立即将患者送入高压氧舱里治疗。结果:5例单耳全聋患者中,3例明显恢复,1例达到轻度恢复标准,1例无效。结论:突发性耳聋病程超过1个月,部分患者应用高压氧仍有一定治疗效果,具有补救治疗价值。