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91.
92.
De-Shuai Kong Heng-Le Zhang Xiu-Lei Zhao Yu Meng Wei Chai Zhen-Yong Wang 《International wound journal》2023,20(9):3682-3689
A meta-analysis was conducted to assess the impact of robotic and laparoscopic pancreaticoduodenectomies on postoperative surgical site wound infections. A comprehensive computerised search of databases, such as PubMed, EMBASE, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and Wanfang Data, was performed to identify studies comparing robotic pancreaticoduodenectomy (PD) with laparoscopicPD. Relevant studies were searched from the inception of the database construction until April 2023. The meta-analysis outcomes were analysed using odds ratios (OR) with corresponding 95% confidence intervals (CI). The RevMan 5.4 software was used for the meta-analysis. The findings of the meta-analysis showed that patients who underwent laparoscopic PD had a significantly lower incidence of surgical-site wound (16.52% vs. 18.92%, OR: 0.78, 95% CI: 0.68–0.90, P = .0005), superficial wound (3.65% vs. 7.57%, OR: 0.51, 95% CI: 0.39–0.68, P < .001), and deep wound infections (1.09% vs. 2.23%, OR: 0.53, 95% CI: 0.34–0.85, P = .008) than those who received robotic PD. However, because of variations in sample size between studies, some studies suffered from methodological quality deficiencies. Therefore, further validation of this result is needed in future studies with higher quality and larger sample sizes. 相似文献
93.
94.
Vascular anatomy of the jejunal mesentery and complications associated with division of the first jejunal venous trunk during pancreaticoduodenectomy 下载免费PDF全文
95.
Combined liver transplant and pancreaticoduodenectomy for inflammatory hilar myofibroblastic tumor: Case report and review of the literature 下载免费PDF全文
Jennifer Berumen Patrick McCarty Jun Mo Kimberly Newton Timothy Fairbanks Kristin Mekeel Alan Hemming 《Pediatric transplantation》2017,21(2)
IMT, previously known as IPT, is a relatively rare tumor that was originally described in the lungs, but case reports have reported the tumor in almost every organ system. Surgical resection is typically the mainstay of therapy; however, tumors have also been shown to respond to chemotherapy or anti‐inflammatory therapy and some have spontaneously regressed. We present a literature review and case report representing the first documentation to date of liver transplant combined with PD for surgical resection of a myofibroblastic tumor non‐responsive to medical therapy. 相似文献
96.
Arsen Osipov Jason Naziri Andrew Hendifar Deepti Dhall Joanne K. Rutgers Shefali Chopra Quanlin Li Mourad Tighiouart Alagappan Annamalai Nicholas N. Nissen Richard Tuli 《Journal of gastrointestinal oncology.》2016,7(2):239-247
Background
Adjuvant chemoradiotherapy (CRT) in the treatment of pancreatic ductal adenocarcinoma (PDA) is controversial. Minimal data exists regarding the clinical significance of margin clearance distance and lymph node (LN) parameters, such as extent of dissection and LN ratio. We assessed the impact of these variables on clinical outcomes to more clearly define the subset of patients who may benefit from adjuvant radiotherapy (RT).Methods
We identified 106 patients with resected stage 1-3 PDA from 2007-2013. Resection margins were categorized as positive (tumor at ink), ≤1, or >1 mm. LN evaluation included total number examined (NE), number of positive nodes (NP), ratio of NP to NE (NR), extent of dissection, and positive periportal LNs. The impact of these variables was assessed on disease-free survival (DFS) and overall survival (OS) using multivariate cox proportional hazards modeling.Results
In patients receiving adjuvant chemotherapy (CT) alone, greater margin clearance led to improved DFS (P=0.0412, HR =0.51). Range of NE was 4-37, with a mean of 19. NE was not associated with DFS or OS, yet absolute NP of 5 or more was associated with a significantly worse DFS (P=0.005). Whereas periportal lymphadenectomy did not result in improved DFS or OS, patients with positive periportal LN had worse clinical outcomes (DFS, P=0.0052; OS, P=0.023). The use of adjuvant CRT was associated with improved OS (P=0.049; HR=0.29).Conclusions
In patients receiving adjuvant CT alone, there was a clinically significant benefit to clearing the surgical margin beyond tumor at ink. Having ≥5 NP and positive periportal LN led to significantly worse clinical outcomes. The addition of adjuvant RT to CT in resected PDA improved OS. A comprehensive evaluation of resection margin distance and LN parameters may identify more patients at risk for locoregional failure who may benefit from adjuvant CRT. 相似文献97.
John S. Fallick M.D. David R. Farley M.D. Michael B. Farnell M.D. Duane M. Ilstrup M.S. Charles M. Rowland M.S. 《Journal of gastrointestinal surgery》1999,3(2):156-161
The utility of placing biliary, pancreatic, or enteric "venting"tubes (externally draining devices traversing the bowel or
bile duct that have their distal tip located intraluminally near the biliary or pancreatic anastomosis) when performing a
pancreaticoduodenectomy has received little attention to date. We hypothesize that these venting tubes do not decrease the
morbidity or mortality associated with pancreatico-duodenectomy and may actually be a source of additional morbidity. To characterize
our use of and the effect of these drains, we retrospectively analyzed 136 pancreaticoduodenectomies (127 partial, 9 total)
performed over a 24-month period. Venting drain use, drain type and size, drain location, duration of intubation, hospital
course, and postoperative complications were noted. Venting tubes were used in 80 patients (59%). The use of these drains
had no significant relationship to postoperative length of stay, the development of major complications, overall morbidity,
or mortality (P >0.05). Such drains also did not significantly shorten the length of hospital stay (P >0.05) or improve outcome when available to augment local control following luminal leak (n = 6) or regional abscess (n =
7). These drains were removed at a median interval of 29 days postoperatively (range 6 to 77 days). Seven patients had complications
that were directly related to the venting drain; four of these patients had a documented infra-abdominal luminal leak from
the site of drain removal, whereas the other three were hospitalized for presumed leakage secondary to immediate, severe abdominal
pain following removal of the drain. These seven patients were elderly (mean age 70 years) and often harbored pancreatic ductal
carcinoma (n = 6). Intraluminal drains afford no distinct advantage in terms of shortening the postoperative length of stay,
decreasing operative morbidity and mortality, or improving local control with regional sepsis in pancreaticoduodenectomies.
Furthermore, they may add an additional source of morbidity and we no longer employ them routinely. 相似文献
98.
Is CT angiography sufficient for prediction of resectability of periampullary neoplasms? 总被引:3,自引:0,他引:3
Pierre F. Saldinger M.D. Melissa Reilly R.N. Kevin Reynolds M.D. Vassilios Raptopoulos M.D. Ram Chuttani M.D. Michael L. Steer M.D. Jeffrey B. Matthews M.D. 《Journal of gastrointestinal surgery》2000,4(3):233-239
The optimal preoperative evaluation of periampullary neoplasms remains controversial. The aim of this study was to analyze
the accuracy of helical computed tomography (CT) and CT angiography with three-dimensional reconstruction in predicting resectability.
Between March 1996 and May 1999, a total of 100 patients with periampullary neoplasms were prospectively staged by helical
CT and CT angiography with three-dimensional reconstruction. Vascular involvement was graded from 0 to 4, with grade 0 representing
no vascular involvement and grade 4 total encasement of either the superior mesenteric vein or artery. Patients with grade
4 lesions were considered unresectable. Sixty-eight patients underwent surgical exploration with intent to perform a pancreaticoduodenectomy.
Forty-four lesions were grade 0, five were grade 1, eight were grade 2, and 11 were grade 3. Resectability for grades 0 to
3 was 96%, l00%, 50%, and 9%, respectively, for an overall resectability rate of 76%. Resectability in patients with vascular
encroachment (grade 2) is usually determined by the extent of local disease rather than the presence of extrapancreatic disease.
Resection is rarely possible in patients with evidence of vascular encasement (grade 3). Additional imaging modalities such
as diagnostic laparoscopy are superfluous in patients with no evidence of local vascular involvement on CT angiography (grades
0 and 1) because of the high resectability rate and infrequency of unsuspected distant metastatic deposits. 相似文献
99.
Takanori Sakaguchi Satoshi Nakamura Shohachi Suzuki Yoshimitsu Kojima Yasuo Tsuchiya Hiroyuki Konno Joji Nakaoka Raisuke Nishiyama 《Journal of hepato-biliary-pancreatic sciences》2000,7(2):193-197
Marginal ulceration is a serious problem after both standard pancreaticoduodenectomy (PD) and pylorus‐preserving pancreaticoduodenectomy (PPPD). The relationship between this complication and the method of reconstruction after PPPD was analyzed in this study. Patients who underwent standard PD (n = 72) or PPPD (n = 28) in the 20‐year period from 1978 to 1997 were retrospectively reviewed. After PPPD, 4 patients (14.3%) developed marginal ulceration on the jejunal side of the duodenojejunal anastomosis, while none of the patients had marginal ulceration after standard PD. The marginal ulcer occurred in 3 of 14 patients treated with the Roux‐en‐Y method, and in 1 of 9 treated with pancreatogastrostomy. In the Roux‐en‐Y method, the anal jejunal loop anastomosed to the bulb was directly exposed to gastric juice without neutralization by pancreatic juice from the oral jejunal limb. Of the 4 patients with marginal ulceration, 2 of those treated by the Roux‐en‐Y method required gastrectomy; the other 2 patients were treated medically. Our analysis of the literature showed that the Roux‐en‐Y method had the highest incidence of marginal ulcerations. The gastrointestinal reconstruction method without a mixture of gastric juice and pancreatic juice may be a causal factor in the marginal ulceration that occurs after PPPD. In reconstruction after PPPD, we should not create a jejunal loop that is exposed to gastric juice alone. 相似文献
100.
Shang-Yu Wang Yu-Liang Hung Chih-Chieh Hsu Chia-Hsiang Hu Ruo-Yi Huang Chang-Mu Sung Yan-Rong Li Hao-Wei Kou Ming-Yang Chen Shih-Chun Chang Chao-Wei Lee Chun-Yi Tsai Keng-Hao Liu Jun-Te Hsu Chun-Nan Yeh Ta-Sen Yeh Tsann-Long Hwang Yi-Yin Jan Miin-Fu Chen 《Nutrients》2021,13(11)
Numerous strategies for perioperative nutrition therapy for patients undergoing pancreaticoduodenectomy (PD) have been proposed. This systematic review aimed to summarize the current relevant published randomized controlled trials (RCTs) evaluating different nutritional interventions via a traditional network meta-analysis (NMA) and component network meta-analysis (cNMA). EMBASE, MEDLINE, the Cochrane Library, and ClinicalTrials.gov were searched to identify the RCTs. The evaluated nutritional interventions comprised standard postoperative enteral nutrition by feeding tube (Postop-SEN), preoperative enteral feeding (Preop-EN), postoperative immunonutrients (Postop-IM), preoperative oral immunonutrient supplement (Preop-IM), and postoperative total parenteral nutrition (TPN). The primary outcomes were general, infectious, and noninfectious complications; postoperative pancreatic fistula (POPF); and delayed gastric emptying (DGE). The secondary outcomes were mortality and length of hospital stay (LOS). The NMA and cNMA were conducted with a frequentist approach. The results are presented as odds ratios (ORs) and 95% confidence intervals (CIs). Two primary outcomes, infectious complications and POPF, were positively influenced by nutritional interventions. Preop-EN plus Postop-SEN (OR 0.11; 95% CI 0.02~0.72), Preop-IM (OR 0.22; 95% CI 0.08~0.62), and Preop-IM plus Postop-IM (OR 0.11; 95% CI 0.03~0.37) were all demonstrated to be associated with a decrease in infectious complications. Postop-TPN (OR 0.37; 95% CI 0.19~0.71) and Preop-IM plus Postop-IM (OR 0.21; 95% CI 0.06~0.77) were clinically beneficial for the prevention of POPF. While enteral feeding and TPN may decrease infectious complications and POPF, respectively, Preop-IM plus Postop-IM may provide the best clinical benefit for patients undergoing PD, as this approach decreases the incidence of both the aforementioned adverse effects. 相似文献