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41.
Background and aimsBody mass index (BMI) and waist circumference (WC) are commonly used markers of cardiometabolic risk. However, sagittal abdominal diameter (SAD) has been proposed as a possibly more sensitive marker of intra-abdominal obesity. We investigated differences in how SAD, WC, and BMI were correlated with cardiometabolic risk markers.Methods and resultsThis cross-sectional study investigated anthropometric and metabolic baseline measurements of individuals from six trials. Multiple linear regression and (partial) correlation coefficients were used to investigate associations between SAD, WC, and BMI and cardiometabolic risk markers, including components of the metabolic syndrome as well as insulin resistance, blood lipids, and lowgrade inflammation.In total 1516 mostly overweight or obese individuals were included in the study. SAD was significantly more correlated with TG than WC for all studies, and overall increase in correlation was 0.05 (95% CI (0.02; 0.08). SAD was significantly more correlated with the markers TG and DBP 0.11 (95% CI (0.08, 0.14)) and 0.04 (95% CI (0.006, 0.07), respectively compared to BMI across all or most studies.ConclusionThis study showed that no single anthropometric indicator was consistently more strongly correlated across all markers of cardiometabolic risk. However, SAD was significantly more strongly correlated with TG than WC and significantly more strongly correlated with DBP and TG than BMI.  相似文献   
42.
梁兴泽 《现代预防医学》2012,39(14):3718-3719
目的分析矢状窦、镰旁脑膜瘤患者资料,比较经显微外科治疗及常规手术治疗后所取得的疗效。方法采用回顾性分析的方法,比较显微手术治疗组和常规手术组全手术切除率、死亡率、输血量等指标的差异,以评价两种治疗方式的效果。结果显微手术组全切率75.0%,高于常规手术组的46.4%(P﹤0.05);显微手术组死亡率2.27%,输血量平均(364±120)ml,均低于常规治疗组(P﹤0.05)。结论采用显微手术对矢状窦、镰旁脑膜瘤进行治疗,效果优于常规的手术治疗,术前行头颅CT、MRI等全面的辅助检查,根据肿瘤的具体情况制定相应的手术计划,熟练的显微外科技术的应用是取得良好手术效果的保证。  相似文献   
43.
The anatomic pelvic parameter "incidence" - the angle between the line perpendicular to the middle of the sacral plate and the line joining the middle of the sacral plate to the center of the bicoxo-femoral axis - has been shown to be strongly correlated with the sacral slope and lumbar lordosis, and ensures the individual an economical standing position. It is important for determining the sagittal curve of the spine. The angle of incidence has also been shown to depend partly on the sagittal anatomy of sacrum, which is established in childhood while learning to stand and walk. The purpose of this study was (1) to define the relationship between the sacrum and the angle of incidence, and (2) to compare these parameters in three populations: young adults, infants before walking, and patients with spondylolisthesis. Forty-four normal young adults, 32 infants not yet walking and 39 patients with spondylolisthesis due to isthmic spondylolysis underwent a sagittal full-spine radiography. A graphic table and the software for bidimensional study of the sacrum developed by J. Hecquet were used to determine various anatomic and positional parameters. Comparison tests of means, and multiple and partial correlation tests were used. A study of the reliability of the measurements using factorial plan methods was performed. The sagittal anatomic parameters of the sacrum were found to have a close relationship with the pelvic parameter of incidence angle, and therefore with the sagittal balance of the spine. The anatomy of the sacrum in spondylolisthesis patients is particular in that some features are much like those of young infants, but it is more curved and the incidence angle is significantly larger. There is a close relationship between angle of incidence and the slip of spondylolisthesis. All the parameters of young infants are significantly smaller than those of adults. It can be concluded that the sagittal anatomy of the sacrum plays a key role in spinal sagittal balance. The sacral bone is an integral a part of the pelvis and constitutes the undistorted part of the spinal curves. Organization of sagittal curves during growth can be followed up by looking at the sacrum. The sacrum in the spondylolisthesis group differs from the normal, and the greater angle of incidence and sacral slope in this group could predispose to vertebral slip.  相似文献   
44.
Sagittal laxity in vivo after total knee arthroplasty   总被引:1,自引:0,他引:1  
Introduction A stress arthrometry study of 77 knees undergoing total knee arthroplasty was performed to determine the difference in anteroposterior (AP) laxity between posterior cruciate ligament (PCL)-retaining (PCLR) and PCL-substituting (PCLS) prostheses using the Genesis I TKA.Materials and methods Fifty-three knees had PCLR and 24 had PCLS prostheses. The selected patients had successful arthroplasties after a minimum follow-up of 5 years. AP laxity was measured with a KT-2000 arthrometer (Medmetric, San Diego, CA, USA) using standard protocols.Results At 30° of flexion, there was no statistical difference in anterior (PCLR: 4.7 mm, PCLS: 4.5 mm), posterior (PCLR: 1.1 mm, PCLS: 0.7 mm), or total (PCLR: 5.8 mm, PCLS: 5.3 mm) displacement. At 75°, significant differences were seen in both anterior (PCLR: 3.3 mm, PCLS: 2.3 mm) and total (PCLR: 4.8 mm, PCLS: 3.4 mm) displacement (p=0.001 and p=0.009, respectively), although there was no statistical difference in posterior displacement (PCLR: 1.5 mm, PCLS: 1.1 mm).Conclusion The above values are considered the suitable degree of AP laxity in total knee arthroplasty for a satisfactory clinical outcome 5–9 years after surgery. The PCL in a PCLR prosthesis and the central tibial spine and femoral cam in a PCLS prosthesis might play comparable roles in determining the laxity in the posterior direction in these prostheses.  相似文献   
45.
From 1977 to 1996, 210 patients suffering from scaphoce-phaly, have been operated on in our institutions. The surgical technique depended on the patients age. Single wide sagittal synostectomy was performed in 155 babies aged less than 3 months, obtaining good cosmetic results. Patients older than 3 months needed more complex and aggressive procedures to achieve similar results. The conclusions is that sagittal suturectomy is the proper treatment in younger pa-tients under 3 months of age, and that a greater effort must be made to diagnose and treat these patients early. Received: 28 December 1998 Revised: 17 March 2000  相似文献   
46.
In severe forms of osteogenesis imperfecta, multiple compression fractures of the spine, as well as vertebral height shortening could be responsible for an increased thoracic kyphosis or a diminished lumbar lordosis. Theses progressive changes in sagittal shapes of the trunk could be responsible for a global sagittal trunk imbalance. We compare the parameters of sagittal spinopelvic balance in young patients with OI to those parameters in a control group of healthy volunteers. Eighteen patients with osteogenesis imperfecta were compared to a cohort of 300 healthy volunteers. A standing lateral radiograph of the spine was obtained in a standardized fashion. The sacral slope, pelvic tilt, pelvic incidence, lumbar lordosis, thoracic kyphosis, T1 and T9 sagittal offset were measured using a computer-assisted method. The variations and reciprocal correlations of all parameters in both groups according to each other were studied. Comparison of angular parameters between OI patients and control group showed an increased T1T12 kyphosis in OI patients. T1 and T9 sagittal offset was positive in OI patients and negative in control group. This statistically significant difference among sagittal offsets in both groups indicated that OI patients had a global sagittal balance of the trunk displaced anteriorly when compared to the normal population. Reciprocal correlations between angular parameters in OI patients showed a strong correlation between lumbar lordosis (L1L5 and L1S1) and sacral slope. The T9 sagittal offset was also strongly correlated with pelvic tilt. Pelvic incidence was correlated with L1S1 lordosis, T1 sagittal offset and pelvic tilt. In OI patients, the T1T12 thoracic kyphosis was statistically higher than in control group and was not correlated with other shape (LL) or pelvic (SS, PT or PI) parameters. Because isolated T1T12 kyphosis increase without T4T12 significant modification, we suggest that vertebral deformations worsen in OI patients at the upper part of thoracic spine. Further studies are needed to precise the exact location of most frequent vertebral deformities.  相似文献   
47.
目的 分析改良下颌升支矢状劈开术(sagittal split ramas osteotomy,SSRO)临床运用的情况,探讨其在正颌外科广泛应用的可能性.方法 195例患者利用SSRO矫正下颌骨畸形,其中90例采用SSRO传统术式,105例采用改良SSR0,将颊侧垂直骨切口移至颏孔区.结果 所有患者治疗效果良好,并发症与传统方式无明显差异.结论 SSR0改良方式的目的 是增大骨段的接触面积和减少手术创伤.颊侧截骨线前移至颏孔区,接触面积得到较大幅度的增加,有利于骨创伤的固定和愈合.同时,通过手术中细致操作,可以有效防止神经损伤等手术并发症的发生.  相似文献   
48.
The aim of this study was to investigate the possibility of estimating height from length of coronal and sagittal sutures of the skull for the positive identification of the height in forensic investigations concerned with fragmentary skeletal remains. The study was conducted on 87 male bodies subjected to medicolegal autopsy in the Department of Forensic Medicine, Kasturba Medical College, Manipal, South India and the Department of Forensic Medicine, Kasturba Medical College, Mangalore, South India. Length of coronal suture was measured from left pterion at the junction of sphenoparietal with the sphenofrontal suture, along the coronal plane, over the coronal suture to the pterion on the right side. Length of sagittal suture was measured from bregma along the sagittal plane over the sagittal suture to the lambda. The data collected were subjected to statistical methods. Significant correlation was found between height and coronal suture length in males, when compared to sagittal suture. The correlation coefficient between height and coronal suture was 0.363. The correlation coefficient between height and sagittal suture was 0.090. Linear regression equations for stature estimation were derived from coronal suture length in male population. Coronal suture length gives more accurate results in estimating stature than sagittal suture. However, in cases where identification is required by means of only skull, this method could prove useful.  相似文献   
49.

Background Context

Lumbar fusion is a popular and effective surgical option to provide stability and restore anatomy. Particular attention has recently been focused on sagittal alignment and radiographic spinopelvic parameters that apply to lumbar fusion as well as spinal deformity cases. Current literature has demonstrated the effectiveness of various techniques of lumbar fusion; however, comparative data of these techniques are limited.

Purpose

This study aimed to directly compare the impact of various lumbar fusion techniques (anterior lumbar interbody fusion [ALIF], lateral lumbar interbody fusion [LLIF], transforaminal lumbar interbody fusion [TLIF], and posterolateral fusion [PLF]) based on radiographic parameters.

Study Design/Setting

A single-center retrospective study examining preoperative and postoperative radiographs was carried out.

Patient Sample

A consecutive list of lumbar fusion surgeries performed by multiple spine surgeons at a single institution from 2013 to 2016 was identified.

Outcome Measures

Radiographic measurements used included segmental lordosis (SL), lumbar lordosis (LL), pelvic incidence (PI), pelvic incidence-lumbar lordosis (PI-LL) mismatch, anterior and posterior disc height (DH-A, DH-P, respectively), and foraminal height (FH).

Methods

Radiographic measurements were performed on preoperative and postoperative lateral lumbar radiographs on all single-level lumbar fusion cases. Demographic data were collected including age, gender, approach, diagnosis, surgical level, and implant lordosis. Paired sample t test, one-way analysis of variance (ANOVA), McNemar test, and independent sample t test were used to establish significant differences in the outcome measures. Multiple linear regression was performed to determine a predictive model for lordosis from implant lordosis, fusion technique, and surgical level.

Results

There were 164 patients (78 men, 86 women) with a mean age of 60.1 years and average radiographic follow-up time of 9.3 months. These included 34 ALIF, 23 LLIF, 63 TLIF, and 44 PLF surgeries. ALIF and LLIF significantly improved SL (7.9° and 4.4°), LL (5.5° and 7.7°), DH-A (8.8?mm and 5.8?mm), DH-P (3.4?mm and 2.3?mm), and FH (2.8?mm and 2.5?mm), respectively (p≤.003). TLIF significantly improved these parameters, albeit to a lesser extent: SL (1.7°), LL (2.7°), DH-A (1.1?mm), DH-P (0.8?mm), and FH (1.1?mm) (p≤.02). PLF did not significantly alter any of these parameters while significantly reducing FH (?1.3?mm, p=.01). One-way ANOVA showed no significant differences between ALIF and LLIF other than ALIF with greater ΔDH-A (3.0?mm, p=.02). Both ALIF and LLIF significantly outperformed PLF in preoperative to postoperative changes in all parameters p≤.001. Additionally, ALIF significantly outperformed TLIF in the change in SL (6.2°, p<.001), and LLIF significantly outperformed TLIF in the change in LL (5.0°, p=.02). Both outperformed TLIF in ΔDH-A (7.7?mm and 4.7?mm) and ΔDH-P (2.6?mm and 1.5?mm), respectively (p≤.02). ALIF was the only fusion technique that significantly improved the proportion of patients with a PI-LL<10° (0.410.66, p=.02). Lordotic cages had superior improvement of all parameters compared with non-lordotic cages (p<.001). Implant lordosis (m=1.1), fusion technique (m=6.8), and surgical level (m=6.9) significantly predicted postoperative SL (p<.001, R2=0.56).

Conclusions

This study demonstrated that these four lumbar fusion techniques yield divergent radiographic results. ALIF and LLIF produced greater improvements in radiographic measurements postoperatively compared with TLIF and PLF. ALIF was the most successful in improving PI-LL mismatch, an important parameter relating to sagittal alignment. Lordotic implants provided better sagittal correction and surgeons should be cognizant of the impact that these differing implants and techniques produce after surgery. Surgical technique is an important determinant of postoperative alignment and has ramifications upon sagittal alignment in lumbar fusion surgery.  相似文献   
50.

Background Context

Nerve root compression causing symptomatic radiculopathy can occur within the intervertebral foramen. Sagittal magnetic resonance imaging (MRI) sequences are reliable in detection of nerve root contact to intraforaminal disc material, but a clinically relevant classification of degree of contact is lacking.

Purpose

This study aimed to investigate a potential relation of amount of contact between intraforaminal disc material and nerve root to clinical findings and response after periradicular corticosteroid infiltration.

Study Design

A post hoc analysis of a prospective cohort was carried out.

Patient Sample

Patients who underwent computed tomography (CT)-guided periradicular corticosteroid infiltration (L1–L5) at our institution (January 2014 to May 2016) were included.

Outcome Measures

The medical records and radiographic imaging were reviewed.

Methods

T2-weighted MRI of the lumbar spine of patients with single-level symptomatic radiculopathy with (responders, n=28) or without (non-responders, n=14) pain relief after periradicular infiltration with corticosteroids were measured and compared by two independent readers to determine the amount of intraforaminal nerve root contact with the intervertebral disc (“melting” of the T2-hypointense signal). Pain relief was defined with a pain level decrease of >50% on a visual analogue scale and lack of pain relief with a pain level decrease of <25%, respectively. The amount of T2-hypointensity melting of disc and nerve root was categorized to 0%, 1%–25%, and over 25%.

Results

Reader one identified 0% T2-melting in none of the responders, 1%–25% melting in 13 patients (46.4%), 26%–50% in 15 of the 28 patients (53.6%) with pain relief after periradicular corticosteroid infiltration (responders), with a mean amount of T2-melting of 5.9±2.1?mm, whereas the non-responder group had 0% T2-melting in 2 patients (14.3%), 1%–25% T2-melting in 11 patients (78.6%), and 26%–50% in 1 patient (7.1%), with a mean amount of T2-melting of 2.6±1.9?mm (p<.05).Reader two identified 0% T2-melting in none, 1%–25% T2-melting in 15 (53.6%) patients, and 26%–50% in 13 of the 28 responders (46.4%), with mean amount of 6.3±1.9?mm. In the non-responder group 0% T2-melting was seen in 3 patients (21.4%), 1%–25% T2-melting in 10 patients (71.4%), and 26%–50% in 1 patient (7.1%), with a mean amount of T2-melting of 2.7±1.9?mm (p<.05). None of the MRI showed T2-melting in over 50% of the circumference of the intraforaminal nerve root.A T2-melting of >25% had a high specificity of 93% but a sensitivity of 50%, thus a positive likelihood ratio of 7.5, to identify those with a pain relief of more than 50% after infiltration.

Conclusion

The amount of T2-melting of disc material and nerve root on sagittal MRI (>25%) predicts the amount of pain relief by periradicular infiltration in patients with intraforaminal nerve root irritation.  相似文献   
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